ID   A0A177R090_9PROT        Unreviewed;       468 AA.
AC   A0A177R090;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   24-JAN-2024, entry version 18.
DE   SubName: Full=Class II fumarate hydratase {ECO:0000313|EMBL:OAI52855.1};
GN   Name=aspA {ECO:0000313|EMBL:OAI52855.1};
GN   ORFNames=AYO46_04200 {ECO:0000313|EMBL:OAI52855.1};
OS   Betaproteobacteria bacterium SCGC AG-212-J23.
OC   Bacteria; Pseudomonadota; Betaproteobacteria.
OX   NCBI_TaxID=1799662 {ECO:0000313|EMBL:OAI52855.1, ECO:0000313|Proteomes:UP000077532};
RN   [1] {ECO:0000313|Proteomes:UP000077532}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SCGC AG-212-J23 {ECO:0000313|Proteomes:UP000077532};
RA   Choi J., Stepanauskas R., Howe A.;
RL   Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OAI52855.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; LSTF01000030; OAI52855.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A177R090; -.
DR   Proteomes; UP000077532; Unassembled WGS sequence.
DR   GO; GO:0016829; F:lyase activity; IEA:InterPro.
DR   GO; GO:0006099; P:tricarboxylic acid cycle; IEA:InterPro.
DR   CDD; cd01357; Aspartase; 1.
DR   Gene3D; 1.10.40.30; Fumarase/aspartase (C-terminal domain); 1.
DR   Gene3D; 1.20.200.10; Fumarase/aspartase (Central domain); 1.
DR   Gene3D; 1.10.275.10; Fumarase/aspartase (N-terminal domain); 1.
DR   InterPro; IPR024083; Fumarase/histidase_N.
DR   InterPro; IPR018951; Fumarase_C_C.
DR   InterPro; IPR020557; Fumarate_lyase_CS.
DR   InterPro; IPR000362; Fumarate_lyase_fam.
DR   InterPro; IPR022761; Fumarate_lyase_N.
DR   InterPro; IPR008948; L-Aspartase-like.
DR   PANTHER; PTHR42696; ASPARTATE AMMONIA-LYASE; 1.
DR   PANTHER; PTHR42696:SF2; ASPARTATE AMMONIA-LYASE; 1.
DR   Pfam; PF10415; FumaraseC_C; 1.
DR   Pfam; PF00206; Lyase_1; 1.
DR   PRINTS; PR00145; ARGSUCLYASE.
DR   PRINTS; PR00149; FUMRATELYASE.
DR   SUPFAM; SSF48557; L-aspartase-like; 1.
DR   PROSITE; PS00163; FUMARATE_LYASES; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000077532}.
FT   DOMAIN          15..344
FT                   /note="Fumarate lyase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00206"
FT   DOMAIN          410..462
FT                   /note="Fumarase C C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF10415"
SQ   SEQUENCE   468 AA;  50279 MW;  27F6CD8C29D846B8 CRC64;
     MSQPTRTEHD LLGDRAVPAD VYYGIHTLRA LENFAISGTP IAIYPDLVVA LACLKQAAAI
     ANAELGLLDE ERATAIRLAC EAVREGNLHD QFVVDVIQGG AGTSSNMNAN EVICNRALEE
     LGRGKGDYAR LHPLDHVNMS QSTNDVYPTA VKLALQLGIR RLLEEMKFLR EAFAAKAAEF
     THVLKVGRTQ LQDAVPMTLG QEFSTYAVML GEDESRLSEA AGLIREINLG ATAIGTGINA
     HPDYAALVTR RLSEVSGIDF VSSPNLIEAT QDAGSFVQLS GVLKRIAVKL SKVCNDLRLL
     SSGPRAGIGE ISLPAVQAGS SIMPGKVNPV IPEVVNQIAF EVIGNDITVT MAAEAGQLQL
     NAFEPIIAHS LFKSLYHLAA GCRTLGERCV KGITANVERA RSLLDGSTAL VTALTPFIGY
     ARSTEIAQEA LATGARVYDL VLQKKLMSRE ELDRLLSPEM LTRPRSNK
//