ID A0A177WHE6_BATDL Unreviewed; 1244 AA.
AC A0A177WHE6;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE RecName: Full=Bromo domain-containing protein {ECO:0000259|PROSITE:PS50014};
GN ORFNames=BDEG_23022 {ECO:0000313|EMBL:OAJ39155.1};
OS Batrachochytrium dendrobatidis (strain JEL423).
OC Eukaryota; Fungi; Fungi incertae sedis; Chytridiomycota;
OC Chytridiomycota incertae sedis; Chytridiomycetes; Rhizophydiales;
OC Rhizophydiales incertae sedis; Batrachochytrium.
OX NCBI_TaxID=403673 {ECO:0000313|EMBL:OAJ39155.1, ECO:0000313|Proteomes:UP000077115};
RN [1] {ECO:0000313|EMBL:OAJ39155.1, ECO:0000313|Proteomes:UP000077115}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JEL423 {ECO:0000313|EMBL:OAJ39155.1,
RC ECO:0000313|Proteomes:UP000077115};
RG The Broad Institute Genome Sequencing Platform;
RA Birren B., Lander E., Galagan J., Cuomo C., Devon K., Jaffe D., Butler J.,
RA Alvarez P., Gnerre S., Grabherr M., Kleber M., Mauceli E., Brockman W.,
RA Young S., LaButti K., Sykes S., DeCaprio D., Crawford M., Koehrsen M.,
RA Engels R., Montgomery P., Pearson M., Howarth C., Larson L., White J.,
RA O'Leary S., Kodira C., Zeng Q., Yandava C., Alvarado L., Longcore J.,
RA James T.;
RT "The Genome Sequence of Batrachochytrium dendrobatidis JEL423.";
RL Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:OAJ39155.1, ECO:0000313|Proteomes:UP000077115}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JEL423 {ECO:0000313|EMBL:OAJ39155.1,
RC ECO:0000313|Proteomes:UP000077115};
RA Cuomo C.A., Farrer R.A., James T., Longcore J., Birren B.;
RT "Lineage-specific infection strategies underlie the spectrum of fungal
RT disease in amphibians.";
RL Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; DS022302; OAJ39155.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A177WHE6; -.
DR STRING; 403673.A0A177WHE6; -.
DR VEuPathDB; FungiDB:BDEG_23022; -.
DR eggNOG; KOG0008; Eukaryota.
DR Proteomes; UP000077115; Unassembled WGS sequence.
DR GO; GO:0005669; C:transcription factor TFIID complex; IEA:InterPro.
DR GO; GO:0004402; F:histone acetyltransferase activity; IEA:InterPro.
DR GO; GO:0001091; F:RNA polymerase II general transcription initiation factor binding; IEA:InterPro.
DR GO; GO:0017025; F:TBP-class protein binding; IEA:InterPro.
DR GO; GO:0006366; P:transcription by RNA polymerase II; IEA:InterPro.
DR Gene3D; 1.20.920.10; Bromodomain-like; 1.
DR InterPro; IPR001487; Bromodomain.
DR InterPro; IPR036427; Bromodomain-like_sf.
DR InterPro; IPR040240; TAF1.
DR InterPro; IPR022591; TAF1_HAT_dom.
DR PANTHER; PTHR13900; TRANSCRIPTION INITIATION FACTOR TFIID; 1.
DR PANTHER; PTHR13900:SF0; TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 1; 1.
DR Pfam; PF00439; Bromodomain; 1.
DR Pfam; PF12157; DUF3591; 1.
DR SMART; SM00297; BROMO; 1.
DR SUPFAM; SSF47370; Bromodomain; 1.
DR PROSITE; PS50014; BROMODOMAIN_2; 1.
PE 4: Predicted;
KW Bromodomain {ECO:0000256|PROSITE-ProRule:PRU00035};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000077115}.
FT DOMAIN 1170..1221
FT /note="Bromo"
FT /evidence="ECO:0000259|PROSITE:PS50014"
FT REGION 108..131
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 858..925
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1000..1031
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1043..1068
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 868..894
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 898..914
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1009..1029
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1244 AA; 141799 MW; 4E4D927B95775A19 CRC64;
MLDLRETLNS REATEYLDRI FTSVLEIDDS STGNAADNAF RVQPAADAVD YSNFQELADD
QSSTALLPQS QESVQAHSSY PVPFQPSGFP APFSLQQTVN IQRATDLQDD YDDDGDTAQE
DQHTSQSQPA QSQFMPMIPI STIQPFQNIA SSVPSLPNIP QIMPFMPVFP TVNLNLSQIP
IQAPAKVFTK EQLAKLFPGY DQGRLRFSQL FAGKISKRPT HLRTDISKKL RKDQFYDVMR
DDRDLFVKCI PTRLPIESYK QPLPDHSTDN VVAVSEVVES EKLESKISVV DDHLLAPVML
ESWEENIVWD INDKDEDVPM DFEMPIRRKD RARFRNTHLD KDDWLEAVVF DEDTPSVKVP
FHLDDPRLVI SNETLVSIQK RAKNPPASQS LFYKQRPDGK LIDRFNISED WLYEVTKPRT
ARVRQTHGPV SIQHSLPAIK MHPQYLKPLL QLRELRSFHR PAFKFIIGEV VQFSRPKAVK
KRPKEIDPSD LMRTPKDISL RDTSKFVLVE YSEEYPLLMQ TVGMASLIYN YYRKKDEKDN
FVPKMNNGGA YILESVDASP FFGFGDVRPG ETRQVLYNNL LRAPIFPQNA APTDFLMIRH
SYHGKVKYFI RDIPNMYSVG QIFPVQEVPR PQARKITQSL KQRLQVVSFR LMWKDPFRRL
RFDRMKKFFP MFSDLQIRQK LKEFAQYLKK GENTGWWKLK SSVKLPDEDG IRKIITPEQV
CLYQSTLVGQ QRLRDAGYGN DDLLDLQNEE DESTLDIEVQ LAPWVTTKNF VIAASGKGMV
RLFGRGDPTG CGEGFSYIRA SMKEMFFKSG LSNETKNAFI NAKAQATFHK YSIAEQQKEY
KEEIDRIWTK QLKSLSCTTI PEDTDPADAE LENMRSSKRK LEIEEEKERR RQYGYNDASS
PAPFSPPSMR NDNNQYSDVE DEDAGSMMGS TLAGKNKVLV ISRMIRNDQG ELDWKSEVIT
DGRVINAYLR HRSIIEKIDE GDENFDISLL SEEERRELRQ RKTREHVAQL QTKLGNKPIS
GNPNEAAHSS SVAPDLDANV LAEQQPSRSL AGANPESTSQ TQLHLQTQPL KTIPPVILKL
NLGNSSSVPT SAQSNASLLP EPTATAIDQT TISSRKRRTI DFHGTNSQPT KAARRGSPKI
ELSNILETII MKLVGTSGAE PLCQPNKADD YAKMIANPKT LDQIRNDVRN FKYKSHIDFC
ADIELVLKNC IMYYGSDHPL TAVSRQLVAQ VKDYITEENS HLTD
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