ID A0A177WN45_BATDL Unreviewed; 2283 AA.
AC A0A177WN45;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE RecName: Full=Dynein heavy chain, cytoplasmic {ECO:0008006|Google:ProtNLM};
GN ORFNames=BDEG_25117 {ECO:0000313|EMBL:OAJ41539.1};
OS Batrachochytrium dendrobatidis (strain JEL423).
OC Eukaryota; Fungi; Fungi incertae sedis; Chytridiomycota;
OC Chytridiomycota incertae sedis; Chytridiomycetes; Rhizophydiales;
OC Rhizophydiales incertae sedis; Batrachochytrium.
OX NCBI_TaxID=403673 {ECO:0000313|EMBL:OAJ41539.1, ECO:0000313|Proteomes:UP000077115};
RN [1] {ECO:0000313|EMBL:OAJ41539.1, ECO:0000313|Proteomes:UP000077115}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JEL423 {ECO:0000313|EMBL:OAJ41539.1,
RC ECO:0000313|Proteomes:UP000077115};
RG The Broad Institute Genome Sequencing Platform;
RA Birren B., Lander E., Galagan J., Cuomo C., Devon K., Jaffe D., Butler J.,
RA Alvarez P., Gnerre S., Grabherr M., Kleber M., Mauceli E., Brockman W.,
RA Young S., LaButti K., Sykes S., DeCaprio D., Crawford M., Koehrsen M.,
RA Engels R., Montgomery P., Pearson M., Howarth C., Larson L., White J.,
RA O'Leary S., Kodira C., Zeng Q., Yandava C., Alvarado L., Longcore J.,
RA James T.;
RT "The Genome Sequence of Batrachochytrium dendrobatidis JEL423.";
RL Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:OAJ41539.1, ECO:0000313|Proteomes:UP000077115}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JEL423 {ECO:0000313|EMBL:OAJ41539.1,
RC ECO:0000313|Proteomes:UP000077115};
RA Cuomo C.A., Farrer R.A., James T., Longcore J., Birren B.;
RT "Lineage-specific infection strategies underlie the spectrum of fungal
RT disease in amphibians.";
RL Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; DS022306; OAJ41539.1; -; Genomic_DNA.
DR STRING; 403673.A0A177WN45; -.
DR VEuPathDB; FungiDB:BDEG_25117; -.
DR eggNOG; KOG3595; Eukaryota.
DR Proteomes; UP000077115; Unassembled WGS sequence.
DR GO; GO:0030286; C:dynein complex; IEA:InterPro.
DR GO; GO:0045505; F:dynein intermediate chain binding; IEA:InterPro.
DR GO; GO:0051959; F:dynein light intermediate chain binding; IEA:InterPro.
DR GO; GO:0008569; F:minus-end-directed microtubule motor activity; IEA:InterPro.
DR GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR Gene3D; 1.10.472.130; -; 1.
DR Gene3D; 1.10.8.1220; -; 1.
DR Gene3D; 1.20.1270.280; -; 1.
DR Gene3D; 1.20.920.20; -; 1.
DR Gene3D; 1.20.920.30; -; 1.
DR Gene3D; 3.10.490.20; -; 1.
DR Gene3D; 6.10.140.1060; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 4.
DR Gene3D; 1.10.8.720; Region D6 of dynein motor; 1.
DR InterPro; IPR035706; AAA_9.
DR InterPro; IPR041658; AAA_lid_11.
DR InterPro; IPR042219; AAA_lid_11_sf.
DR InterPro; IPR026983; DHC_fam.
DR InterPro; IPR041589; DNAH3_AAA_lid_1.
DR InterPro; IPR041466; Dynein_AAA5_ext.
DR InterPro; IPR041228; Dynein_C.
DR InterPro; IPR043160; Dynein_C_barrel.
DR InterPro; IPR024743; Dynein_HC_stalk.
DR InterPro; IPR024317; Dynein_heavy_chain_D4_dom.
DR InterPro; IPR004273; Dynein_heavy_D6_P-loop.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR46961; DYNEIN HEAVY CHAIN 1, AXONEMAL-LIKE PROTEIN; 1.
DR PANTHER; PTHR46961:SF5; DYNEIN HEAVY CHAIN 6; 1.
DR Pfam; PF12775; AAA_7; 1.
DR Pfam; PF12780; AAA_8; 1.
DR Pfam; PF12781; AAA_9; 1.
DR Pfam; PF17857; AAA_lid_1; 1.
DR Pfam; PF18198; AAA_lid_11; 1.
DR Pfam; PF17852; Dynein_AAA_lid; 1.
DR Pfam; PF18199; Dynein_C; 1.
DR Pfam; PF03028; Dynein_heavy; 1.
DR Pfam; PF12777; MT; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000077115}.
FT DOMAIN 84..211
FT /note="Dynein heavy chain AAA 5 extension"
FT /evidence="ECO:0000259|Pfam:PF17852"
FT DOMAIN 431..521
FT /note="Dynein heavy chain 3 AAA+ lid"
FT /evidence="ECO:0000259|Pfam:PF17857"
FT DOMAIN 574..834
FT /note="Dynein heavy chain AAA module D4"
FT /evidence="ECO:0000259|Pfam:PF12780"
FT DOMAIN 848..1194
FT /note="Dynein heavy chain coiled coil stalk"
FT /evidence="ECO:0000259|Pfam:PF12777"
FT DOMAIN 1221..1442
FT /note="Dynein heavy chain ATP-binding dynein motor region"
FT /evidence="ECO:0000259|Pfam:PF12781"
FT DOMAIN 1687..1800
FT /note="Dynein heavy chain region D6 P-loop"
FT /evidence="ECO:0000259|Pfam:PF03028"
FT DOMAIN 1832..1970
FT /note="Dynein heavy chain AAA lid"
FT /evidence="ECO:0000259|Pfam:PF18198"
FT DOMAIN 1977..2278
FT /note="Dynein heavy chain C-terminal"
FT /evidence="ECO:0000259|Pfam:PF18199"
FT COILED 1074..1125
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1383..1410
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1435..1462
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 2283 AA; 260068 MW; 972936C95BD0397C CRC64;
MNTLLDDNKK LCLSSGEIIK MSPSQTMMFE VQDLAFASPA TVSRCGMIYM EPDALGILPL
CVSWFKLQHT TLGENLASVL REQLEPILEH YLNASLDFVR KSVKEAVPTT NGGLVASLLR
ILDSLFKPLA NPVGDKQPIQ SLEFKKVIGP LFIFALVWSV GATGDTEGRK KFDSWLRGQL
VSHSCSTVIP DSGLVYDFTF NIEKLEWINW MHLLESDNED QAFKSGKSDM IVQTMDTVRN
SFLIDILVKN DYHVLCTGPT GTGKSITIQQ KLMKGLDVNW TPLIINFSAR TSANQTQDLI
DSKLEKRRKG VFGPPVGKKF IIFIDDLNMP QLDICNAQPP IELLRQWMDC QGWYDRKNIG
KFMEIVDISF ICAMGPPGGG RNPTTSRFLR HFNLIGFVEM ENTSLKRIFT TILGGFLSKF
PPEITKSTDS LVDASIAIYN TIRSELLPTP TKSHYTFNLR DLAKVIQGVL SADLKTVNVE
TDIVRLWIHE CQRVFQDRLV DNVDKNWFKT LMMNTMNDKL DLSWSEVVIS EPLLYGDYMT
PGADPKIYTE DLRRLVKLAE EYLDDYNGSS TSPMKLVMFL DAIEHVSRIC RIIRQPGGHA
LLLGVGGSGR QSLSRLATFM EEFEQFQIEI SKNYGQTEWR DDLKKVLFAA GLEGKPTVFL
YTDTQIVSES NLEDINNILN GGDVPNIYTS EEMDRILNGV RPIAAEQAIP STRENLFALY
IQRIRTNLHL IVCMSPIGDP FRNRLRMFPS LVNCCTIDWF STWPEDALRS VAANSISEIS
DLGSEHVIDG IVNLCVFMHE SVRERCITYR SELSRNNYVT PKSYLELLGL YKRLLEKKRN
ELISLRKRTA TGLEKLLNAT KEVEILQEEL EAMQPMLMQT SQETEYAMKK IAVDKIKAEE
IKENVIKEEL ASSKKAEETK AIAEDAKRDL DEALPALDAA VESLNSLSKN DIIEVRSMQR
PPEGVKLVIE AICIMKGIKP KKIDGDKPGK KIDDYWEPGR ALLADPQRFL DSLMNFDKEN
IAEATVQKIK PYIDSPEFQV SVISRVSRAA TSMCQWVRAM EKYYWVSRSV APKRARLQEA
QESLDATLKA LAELKKKMKE AEMNIKEMEK KYAESVAKKE ELSRKVEECN VKLSRAGKLI
SGLSGEKQRW ALAVDQFDMK IGNIIGDILL ASGAIAYLGP FTAEYRSLLM REWIGSVLQL
KIPHSENTSL WDALGDNVKL REWELFGLPK DSLSRDNAII VQNSRRWPLL IDPQGQANKW
IRNMEREHSL DIVKLTDRDF LRTLENAIRF GKSVLLENVG EKLDPALEPI LMRQTFKQGG
STVIKVGDSI LPYHDDFKFY ITTKLPNPHY SPETSATATL VNFTLAPSGL EDQLLAIVVA
NERPDLEEAK NQLTINNAQM KRELKEIEDK ILYLLSSVQG SPVDDERLIE TLGASKETSE
EIQQKVAAAE QTEREIDTTR NKYVPVAVRT RILFFCITEL ASIDPMYQYS LNWFMNLFTS
AISHSEKSDD IEQRVFNIND YFTFSLFTNV CRSLFEKHKL LFSFLLTIRI LMNDNKIDMD
EWRFLLTGSA AHDKTLQNPA PDWLSVQSWN AIMGLSTLAF FTDFDTGFTE SIDHYMAIFD
SSTPHREPLP GIWQDKLDGF QKLLLLRCLR ADCVTSGIQD FVAAQLEERF IEPQTSDLSA
LFKESTPLTP LIFVLSPGAD PANSLYKFAE EMRMSKKLTS VSLGQGQGPR AEALMKEGME
RGLWILLQNC HLSPSWMPSL DRVIDSITMD KVHRDFRLWL TSMPTPKFPV TILQNGVKTT
LEPPNGIKAN LMRNYSTFND EMLNQCQKPV EWKKLLFSLC FFHAVIQERR KFGALGWNIP
YEFTDGDLRI CIRQLKMFLE EYEEIPFKVL KYTVGEINYG GRVTDDWDRR LIMGILEDYY
TPKVLEDTYL FSSSVVYKSI PADSYNSYKA YIKSLPIDET TEIFAMHNNA NITFAQKKTY
DLFESLLTLM PKSSKSSSGK TRDEQLSDIA AMIQQKIPKP FSMDYVTKKY PIEYKESMST
VLVQEVIRYN RLLSTIHSTT IEMIKALKGL VVLSESLETM CNSMYINQVP EIWAAKAYPS
LKSLASWGVD LTLRCEFIQK WIDQGIPTVF WISGFFFPQA FLTGTLQNYA RKYVVSIDLL
GFEFKVMDTK WDEFRSKPSD GCYIRGLFLE GARWDPVQRC LTESRPKELY TEMSVLWLLP
KPNRKKPESG IYNCPVYKTL TRAGTLSTTG HSTNYVLTIE LPSNLPQLHW IKRGVSLITS
LAW
//
