ID A0A177WUM2_BATDL Unreviewed; 829 AA.
AC A0A177WUM2;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=W2 domain-containing protein {ECO:0000259|PROSITE:PS51363};
GN ORFNames=BDEG_27107 {ECO:0000313|EMBL:OAJ43787.1};
OS Batrachochytrium dendrobatidis (strain JEL423).
OC Eukaryota; Fungi; Fungi incertae sedis; Chytridiomycota;
OC Chytridiomycota incertae sedis; Chytridiomycetes; Rhizophydiales;
OC Rhizophydiales incertae sedis; Batrachochytrium.
OX NCBI_TaxID=403673 {ECO:0000313|EMBL:OAJ43787.1, ECO:0000313|Proteomes:UP000077115};
RN [1] {ECO:0000313|EMBL:OAJ43787.1, ECO:0000313|Proteomes:UP000077115}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JEL423 {ECO:0000313|EMBL:OAJ43787.1,
RC ECO:0000313|Proteomes:UP000077115};
RG The Broad Institute Genome Sequencing Platform;
RA Birren B., Lander E., Galagan J., Cuomo C., Devon K., Jaffe D., Butler J.,
RA Alvarez P., Gnerre S., Grabherr M., Kleber M., Mauceli E., Brockman W.,
RA Young S., LaButti K., Sykes S., DeCaprio D., Crawford M., Koehrsen M.,
RA Engels R., Montgomery P., Pearson M., Howarth C., Larson L., White J.,
RA O'Leary S., Kodira C., Zeng Q., Yandava C., Alvarado L., Longcore J.,
RA James T.;
RT "The Genome Sequence of Batrachochytrium dendrobatidis JEL423.";
RL Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:OAJ43787.1, ECO:0000313|Proteomes:UP000077115}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JEL423 {ECO:0000313|EMBL:OAJ43787.1,
RC ECO:0000313|Proteomes:UP000077115};
RA Cuomo C.A., Farrer R.A., James T., Longcore J., Birren B.;
RT "Lineage-specific infection strategies underlie the spectrum of fungal
RT disease in amphibians.";
RL Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; DS022310; OAJ43787.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A177WUM2; -.
DR STRING; 403673.A0A177WUM2; -.
DR VEuPathDB; FungiDB:BDEG_27107; -.
DR Proteomes; UP000077115; Unassembled WGS sequence.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR GO; GO:0031369; F:translation initiation factor binding; IEA:InterPro.
DR CDD; cd11558; W2_eIF2B_epsilon; 1.
DR Gene3D; 1.25.40.180; -; 1.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR003307; W2_domain.
DR InterPro; IPR044123; W2_eIF2B_epsilon.
DR PANTHER; PTHR45887; TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT EPSILON; 1.
DR PANTHER; PTHR45887:SF1; TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT EPSILON; 1.
DR Pfam; PF02020; W2; 1.
DR SMART; SM00515; eIF5C; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR PROSITE; PS51363; W2; 1.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Reference proteome {ECO:0000313|Proteomes:UP000077115}.
FT DOMAIN 499..677
FT /note="W2"
FT /evidence="ECO:0000259|PROSITE:PS51363"
FT REGION 149..179
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 436..502
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 671..698
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 713..742
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 759..781
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 454..484
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 485..500
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 716..732
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 829 AA; 92034 MW; 1092DDC5EA127669 CRC64;
MTSSFLSSWL WLKPVQSIDG ILTINRTTLY ATITTIACLS TYNYRQTLFV FYRHILASWS
TTRTTLAVVL ASVVGPLVLL NLNDSLGIES WARCVVRYYR RKRRRLLQQQ QLLLQQKQLV
LHCNDPPIIR KDSSKPDSIP SALRCSFSST GSQSASPVSP FESSLPLPMT RSQSLPHTSA
PRILGISKTD SSSNIQTVSS HLPVEYPTNS SLYSASILPL YTYSLGNTSD ASVAHSTCSS
TFNTAISTDF NPSSTSTRAY VRRLEAQVRL LCRKREAMVE SVRGLKKEVA LEREARFVVE
TYLNERLRRM ELELDFRDNE ILKLRDRQRE MDASMGYSDV DDYDANDETD SSFGKINAST
ALHSTLPSCS TLLSTKSPLK ACTIRAPIPI CILNNNTPDS PTSNQLSVDD TVLFGESPRS
STTACIAPCS NIFSKSVDMD DSDEDDETYS KNESASDTES IDTSTASIQH DGSSVSTDTH
LTPIGRSSNK HDDEDFGYGS EESTSSHILS MALPHSFDEY APAKIYQELL AEVAPSLLLV
DIDDLATTLH ATSHQCLVAV IQAALQICER KGHWMCKVKL VEFFQRYHIL ISRFIDNQSD
QLLALAAIEE YCNGSLKRRA YHLKIIMCLY QLDVVDAELL ITWFDRGIAT NDLNDVRNLC
SEFMDWLEEQ VSDDDDDDSS SDDSEHDGSH SDGPADPDAL WIVPAVTIVS TDTVHNDDSM
RAHDHDESSR KPPLLVSTDS SAPAVPSKLI EHSLLLQTHA SDSEDDASNS EDLGEDEDDT
FDASYAHMDP ELCFQSPLMF SAHVLNEVGC ERTESFSSSG SRKKVTFST
//
