ID A0A177YHA8_9NOCA Unreviewed; 551 AA.
AC A0A177YHA8;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=DNA helicase {ECO:0000256|ARBA:ARBA00012551};
DE EC=3.6.4.12 {ECO:0000256|ARBA:ARBA00012551};
GN ORFNames=A3K89_03780 {ECO:0000313|EMBL:OAK54498.1};
OS Rhodococcus kyotonensis.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Nocardiaceae;
OC Rhodococcus.
OX NCBI_TaxID=398843 {ECO:0000313|EMBL:OAK54498.1, ECO:0000313|Proteomes:UP000077519};
RN [1] {ECO:0000313|EMBL:OAK54498.1, ECO:0000313|Proteomes:UP000077519}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KB10 {ECO:0000313|EMBL:OAK54498.1,
RC ECO:0000313|Proteomes:UP000077519};
RA Jeong H., Hong C.E., Jo S.H., Park J.M.;
RT "Genome sequence of Rhodococcus kyotonensis KB10.";
RL Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC Evidence={ECO:0000256|ARBA:ARBA00001665};
CC -!- SIMILARITY: Belongs to the helicase family. RAD25/XPB subfamily.
CC {ECO:0000256|ARBA:ARBA00006637}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OAK54498.1}.
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DR EMBL; LVHI01000012; OAK54498.1; -; Genomic_DNA.
DR RefSeq; WP_068424777.1; NZ_LVHI01000012.1.
DR AlphaFoldDB; A0A177YHA8; -.
DR Proteomes; UP000077519; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR CDD; cd18789; SF2_C_XPB; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR032438; ERCC3_RAD25_C.
DR InterPro; IPR006935; Helicase/UvrB_N.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR032830; XPB/Ssl2_N.
DR PANTHER; PTHR11274:SF0; GENERAL TRANSCRIPTION AND DNA REPAIR FACTOR IIH HELICASE SUBUNIT XPB; 1.
DR PANTHER; PTHR11274; RAD25/XP-B DNA REPAIR HELICASE; 1.
DR Pfam; PF16203; ERCC3_RAD25_C; 1.
DR Pfam; PF13625; Helicase_C_3; 1.
DR Pfam; PF04851; ResIII; 1.
DR PRINTS; PR00851; XRODRMPGMNTB.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000313|EMBL:OAK54498.1};
KW Helicase {ECO:0000313|EMBL:OAK54498.1};
KW Hydrolase {ECO:0000313|EMBL:OAK54498.1};
KW Nucleotide-binding {ECO:0000313|EMBL:OAK54498.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000077519}.
FT DOMAIN 192..346
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 401..546
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
SQ SEQUENCE 551 AA; 61019 MW; 8773528F52D8DEC7 CRC64;
MTDGPLIVQS DKTLLLEIDH PQAGEARGAI APFAELERAP EHVHTYRITP LALWNARAAG
HDAEQVVDAL VNYSRYAVPQ PLLVDIVDTM ARYGRLQLVK NPAHGLSLVS LDRAVLTEVM
RHKKIAPMLG AKVDDDTVIV HPSERGHLKQ MLLKIGWPAE DLAGYVDGEA HPIDLDQEGG
HWSLRDYQEM AADSFWAGGS GVVVLPCGAG KTMVGAAAMA KAKATTLILV TNTVAGRQWK
RELIARTSLT EDEIGEYSGE RKEIRPVTIA TYQVITRRTK GEYKHLELFD SRDWGLVIYD
EVHLLPAPVF RMTADLQSRR RLGLTATLVR EDGREGDVFS LIGPKRYDAP WKDIEAQGWI
APAECIEVRV TLTDAERMAY AVAEPEERYK LCSTAHTKIA VVKSILAKHE DAPTLVIGAY
LDQLEELGEA LNAPVIQGST RNKEREQLFD AFRRGEIQTL VVSKVANFSI DLPEASVAVQ
VSGTFGSRQE EAQRLGRLLR PKHDGGQAHF YSVVSRDTLD AEYAAHRQRF LAEQGYAYRI
TDADDMLGPA I
//
