ID A0A178A9D1_9PLEO Unreviewed; 956 AA.
AC A0A178A9D1;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=Coatomer subunit beta {ECO:0000256|PIRNR:PIRNR005727};
DE AltName: Full=Beta-coat protein {ECO:0000256|PIRNR:PIRNR005727};
GN ORFNames=IQ06DRAFT_260389 {ECO:0000313|EMBL:OAK94326.1};
OS Stagonospora sp. SRC1lsM3a.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Pleosporomycetidae; Pleosporales; Massarineae; Massarinaceae; Stagonospora.
OX NCBI_TaxID=765868 {ECO:0000313|EMBL:OAK94326.1, ECO:0000313|Proteomes:UP000077206};
RN [1] {ECO:0000313|EMBL:OAK94326.1, ECO:0000313|Proteomes:UP000077206}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SRC1lsM3a {ECO:0000313|EMBL:OAK94326.1,
RC ECO:0000313|Proteomes:UP000077206};
RG DOE Joint Genome Institute;
RA Zeiner C.A., Purvine S.O., Zink E.M., Wu S., Pasa-Tolic L., Chaput D.L.,
RA Haridas S., Grigoriev I.V., Santelli C.M., Hansel C.M.;
RT "Comparative analysis of secretome profiles of manganese(II)-oxidizing
RT ascomycete fungi.";
RL Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: The coatomer is a cytosolic protein complex that binds to
CC dilysine motifs and reversibly associates with Golgi non-clathrin-
CC coated vesicles, which further mediate biosynthetic protein transport
CC from the ER, via the Golgi up to the trans Golgi network. Coatomer
CC complex is required for budding from Golgi membranes, and is essential
CC for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.
CC {ECO:0000256|PIRNR:PIRNR005727}.
CC -!- SUBUNIT: Oligomeric complex that consists of at least the alpha, beta,
CC beta', gamma, delta, epsilon and zeta subunits.
CC {ECO:0000256|PIRNR:PIRNR005727}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|PIRNR:PIRNR005727}. Golgi
CC apparatus membrane {ECO:0000256|ARBA:ARBA00004255,
CC ECO:0000256|PIRNR:PIRNR005727}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004255, ECO:0000256|PIRNR:PIRNR005727};
CC Cytoplasmic side {ECO:0000256|ARBA:ARBA00004255,
CC ECO:0000256|PIRNR:PIRNR005727}. Cytoplasmic vesicle, COPI-coated
CC vesicle membrane {ECO:0000256|PIRNR:PIRNR005727}; Peripheral membrane
CC protein {ECO:0000256|PIRNR:PIRNR005727}; Cytoplasmic side
CC {ECO:0000256|PIRNR:PIRNR005727}. Membrane
CC {ECO:0000256|ARBA:ARBA00004287}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004287}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004287}.
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DR EMBL; KV441725; OAK94326.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A178A9D1; -.
DR STRING; 765868.A0A178A9D1; -.
DR InParanoid; A0A178A9D1; -.
DR OrthoDB; 151169at2759; -.
DR Proteomes; UP000077206; Unassembled WGS sequence.
DR GO; GO:0030126; C:COPI vesicle coat; IEA:InterPro.
DR GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR GO; GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR002553; Clathrin/coatomer_adapt-like_N.
DR InterPro; IPR011710; Coatomer_bsu_C.
DR InterPro; IPR016460; COPB1.
DR InterPro; IPR029446; COPB1_appendage_platform_dom.
DR PANTHER; PTHR10635; COATOMER SUBUNIT BETA; 1.
DR PANTHER; PTHR10635:SF0; COATOMER SUBUNIT BETA; 1.
DR Pfam; PF01602; Adaptin_N; 1.
DR Pfam; PF07718; Coatamer_beta_C; 1.
DR Pfam; PF14806; Coatomer_b_Cpla; 1.
DR PIRSF; PIRSF005727; Coatomer_beta_subunit; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490, ECO:0000256|PIRNR:PIRNR005727};
KW Cytoplasmic vesicle {ECO:0000256|PIRNR:PIRNR005727};
KW ER-Golgi transport {ECO:0000256|ARBA:ARBA00022892,
KW ECO:0000256|PIRNR:PIRNR005727};
KW Golgi apparatus {ECO:0000256|ARBA:ARBA00023034,
KW ECO:0000256|PIRNR:PIRNR005727};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PIRNR:PIRNR005727};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927,
KW ECO:0000256|PIRNR:PIRNR005727};
KW Reference proteome {ECO:0000313|Proteomes:UP000077206};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PIRNR:PIRNR005727}.
FT DOMAIN 22..492
FT /note="Clathrin/coatomer adaptor adaptin-like N-terminal"
FT /evidence="ECO:0000259|Pfam:PF01602"
FT DOMAIN 680..814
FT /note="Coatomer beta subunit C-terminal"
FT /evidence="ECO:0000259|Pfam:PF07718"
FT DOMAIN 820..946
FT /note="Coatomer beta subunit appendage platform"
FT /evidence="ECO:0000259|Pfam:PF14806"
FT REGION 497..520
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 956 AA; 106466 MW; C7FA9F0C8FA9C3D7 CRC64;
MATFLENSYS LVHQDNAADV PSQNELKQAL EKGNDEQKIE TMKKILSIML NGDPQTGLLM
HIIRFVMPSK SKPLKKLMYF FFEVCPKHDA QGKLRQEWIL VCNAIRFDLQ APNEYVRGNT
LRFVTKLRDA ELVEPLLQPV RQCLTHRHAY VRKNATFAVA SIFTHLPELM PDAPDMLVTF
LDDENDPTCK RNAFAALVSV SHEKALEYLS TVFDAIPNHE ELLLLAELEF IRKDAVVNPQ
NKARYMRLIF DLLESQVSTV IYESAHALTT LTSNPVAVKA AAGKFVELAI KEPDNNVKLI
VLERVDQLRS KHEGVLDDLT MEVLRVLSST DLDVRKKSLN IAMEMISSRN VEEVVLLLKK
ELMKTVDEQY EKNSEYRSLL ISSIHSAAIK FPEVAASVVG SLMDFISDVS SNASAVDVIS
FVKEVVERFP DLRPSIIERL VSTLGEVRAG KVYRGVLWII GEFSLEAKDI RDAWKGIRSS
LGEIPILASE QRLLDDASEG KEDTEQVNGH AKSSAPTGSR KVLADGTYAT ESALTSSAAA
KAKLEAVKNS QKPPLRQLVL DGDYYLATVL SSTLTKLVMR HSELSQDAAR TNALRAEAML
IMISIIRVGQ SQFVKTLIDE DSIDRIMSCV RSLSEFSQRK ELETVFLEDT RKSFAAMVQT
EEKKRAAKEA SERAKSAVNV DDSFNIRQLK KKDADGSDEI EQDLERATGG DTATEDLTSK
LSRVVQLTGF SDSVYAEAYV KVHQFDIVLD VLLVNQTTET LQNLTVEFAT LGDLKVVERP
PTQNVGPHDF INIQATVKVS STDTGVIFGN ILYEGEKGVD SNVVILNDVH VDIMDYIKPA
QCTETQFRTM WTEFEWENKV NINSKAKTLR DFLKQLMAST NMSCLTPEAS MKGDCQFLSA
NLYARSVFGE DALANLSIEK EGDNGPITGF VRIRSRSQGL ALSLGSLKGL NKVGVA
//
