ID   A0A178AK74_9PLEO        Unreviewed;      1040 AA.
AC   A0A178AK74;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   RecName: Full=CNH domain-containing protein {ECO:0000259|PROSITE:PS50219};
GN   ORFNames=IQ06DRAFT_327513 {ECO:0000313|EMBL:OAK97976.1};
OS   Stagonospora sp. SRC1lsM3a.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC   Pleosporomycetidae; Pleosporales; Massarineae; Massarinaceae; Stagonospora.
OX   NCBI_TaxID=765868 {ECO:0000313|EMBL:OAK97976.1, ECO:0000313|Proteomes:UP000077206};
RN   [1] {ECO:0000313|EMBL:OAK97976.1, ECO:0000313|Proteomes:UP000077206}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SRC1lsM3a {ECO:0000313|EMBL:OAK97976.1,
RC   ECO:0000313|Proteomes:UP000077206};
RG   DOE Joint Genome Institute;
RA   Zeiner C.A., Purvine S.O., Zink E.M., Wu S., Pasa-Tolic L., Chaput D.L.,
RA   Haridas S., Grigoriev I.V., Santelli C.M., Hansel C.M.;
RT   "Comparative analysis of secretome profiles of manganese(II)-oxidizing
RT   ascomycete fungi.";
RL   Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; KV441716; OAK97976.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A178AK74; -.
DR   STRING; 765868.A0A178AK74; -.
DR   InParanoid; A0A178AK74; -.
DR   OrthoDB; 38195at2759; -.
DR   Proteomes; UP000077206; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR   GO; GO:0043231; C:intracellular membrane-bounded organelle; IEA:UniProt.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:UniProtKB-UniRule.
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
DR   InterPro; IPR000547; Clathrin_H-chain/VPS_repeat.
DR   InterPro; IPR001180; CNH_dom.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   InterPro; IPR032914; Vam6/VPS39/TRAP1.
DR   InterPro; IPR019452; VPS39/TGF_beta_rcpt-assoc_1.
DR   InterPro; IPR019453; VPS39/TGF_beta_rcpt-assoc_2.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   PANTHER; PTHR12894; CNH DOMAIN CONTAINING; 1.
DR   PANTHER; PTHR12894:SF27; TRANSFORMING GROWTH FACTOR-BETA RECEPTOR-ASSOCIATED PROTEIN 1; 1.
DR   Pfam; PF00780; CNH; 1.
DR   Pfam; PF10366; Vps39_1; 1.
DR   Pfam; PF10367; Vps39_2; 1.
DR   SUPFAM; SSF48452; TPR-like; 1.
DR   SUPFAM; SSF50978; WD40 repeat-like; 1.
DR   PROSITE; PS50236; CHCR; 1.
DR   PROSITE; PS50219; CNH; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000077206}.
FT   DOMAIN          18..333
FT                   /note="CNH"
FT                   /evidence="ECO:0000259|PROSITE:PS50219"
FT   REGION          445..531
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        497..531
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1040 AA;  115960 MW;  FD2D953A804FCCD1 CRC64;
     MLSAFTARPI VELKQRDKSK IESILAYGDR VLVGLNTGSL RIYRVNDALD DADDDAQQNG
     DNARPADLLR EEDKFSRRPI QQLAIIKEAN ILISLSDNHV SIHDLQTYTL QEKLERTRGA
     TTFAAASNIV KDPSTGIPSI VSRLAVAVKR KVILWTWQDM ELAGDAVEIS LMATVKSLTW
     ASGTKIVAGM DPGFVMVDIE TQDVQDIVKP GALGEGGSQA GARFGAVSSS GMGYMGMASW
     VPKPLATRLG EGEMLLAKDV NSLFIDTEGN ALEKRQVPWH AAPEMIAYSY PYMLTLNPPS
     KGSLEVRNPD TLNMLQSISL PNVTFLHVPQ PNISLAHAGK GFLVASDRCI WRMGAQSYET
     QMDELVAGTR YDEALSLLNM LEDTLLLDKE DRVREIMMLK AHALFDEKQY REAMDLFTDA
     KAPPERVIAL YPRAIAGDLA AEDNVQGAES VAEDDDANSD RPTADSKEST PAPTATIGRS
     MMGRLVGGGR KADTDTASIR SSVKEEASES TPIKKRGTDT SQSDKQNGEK DFKDSVRALQ
     SFLAQCRVQI KRYIDTDGNL LEPLQEPSES QPEDYKPPFY NFIQLSRMTT QVDWKAKLLE
     VAQLVDTTLF RAYMIASPSL AGPLFRLPNF CEPDVVQEKL YETGRYADLI DFLHGKRLHR
     QALELLEKFS KNEADEDVAT ALQGPQRTVG YLKQLPPEMI DLILEFAEWP LRSDPKLGMD
     VFLADTHNAE NIPRDKVVNF LQQIDLKLAV RYLEHIVEEL DETDPEFHQR LVDLLLERLR
     SGDFESDEEK AEWRKRLQLF LKTSRNYNNY RVFQQLPSTD PDYYEARAIV LSKMGQHKQA
     LAIYVFQLQD YHKAEEYCNE VYMSVPASTN MDESEPSIYH VLLSLYLTPS APNKPNWPPA
     LELLSKHGAR LPASSTLELV PPTLPVQELE SYFKGRIRNA NSVLNEERIV AKLRGVEKAA
     VIERVLLGEG KVGRDGRVVA GGLNRRVVID EDRHCAVCHK RFGGSAIRVY PDNSVVHSGC
     MRGSVGRTKS SGVNAGAGWR
//