ID A0A178DJR0_9PLEO Unreviewed; 934 AA.
AC A0A178DJR0;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 28-JUN-2023, entry version 25.
DE RecName: Full=ER membrane protein complex subunit 1 {ECO:0000256|ARBA:ARBA00020824};
GN ORFNames=IQ07DRAFT_523550 {ECO:0000313|EMBL:OAL43760.1};
OS Pyrenochaeta sp. DS3sAY3a.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Pleosporomycetidae; Pleosporales; Pleosporineae; Cucurbitariaceae;
OC Pyrenochaeta.
OX NCBI_TaxID=765867 {ECO:0000313|EMBL:OAL43760.1, ECO:0000313|Proteomes:UP000077535};
RN [1] {ECO:0000313|EMBL:OAL43760.1, ECO:0000313|Proteomes:UP000077535}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DS3sAY3a {ECO:0000313|EMBL:OAL43760.1,
RC ECO:0000313|Proteomes:UP000077535};
RG DOE Joint Genome Institute;
RA Zeiner C.A., Purvine S.O., Zink E.M., Wu S., Pasa-Tolic L., Chaput D.L.,
RA Haridas S., Grigoriev I.V., Santelli C.M., Hansel C.M.;
RT "Comparative analysis of secretome profiles of manganese(II)-oxidizing
RT ascomycete fungi.";
RL Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBUNIT: Component of the ER membrane protein complex (EMC).
CC {ECO:0000256|ARBA:ARBA00011276}.
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000256|ARBA:ARBA00004115}; Single-pass type I membrane protein
CC {ECO:0000256|ARBA:ARBA00004115}. Membrane
CC {ECO:0000256|ARBA:ARBA00004479}; Single-pass type I membrane protein
CC {ECO:0000256|ARBA:ARBA00004479}.
CC -!- SIMILARITY: Belongs to the EMC1 family.
CC {ECO:0000256|ARBA:ARBA00007904}.
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DR EMBL; KV441665; OAL43760.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A178DJR0; -.
DR STRING; 765867.A0A178DJR0; -.
DR InParanoid; A0A178DJR0; -.
DR OrthoDB; 37872at2759; -.
DR Proteomes; UP000077535; Unassembled WGS sequence.
DR GO; GO:0072546; C:EMC complex; IEA:InterPro.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR InterPro; IPR026895; EMC1.
DR InterPro; IPR011678; EMC1_C.
DR InterPro; IPR018391; PQQ_beta_propeller_repeat.
DR InterPro; IPR002372; PQQ_repeat.
DR InterPro; IPR011047; Quinoprotein_ADH-like_supfam.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR PANTHER; PTHR21573:SF0; ER MEMBRANE PROTEIN COMPLEX SUBUNIT 1; 1.
DR PANTHER; PTHR21573; UNCHARACTERIZED; 1.
DR Pfam; PF07774; EMC1_C; 1.
DR Pfam; PF13360; PQQ_2; 1.
DR SMART; SM00564; PQQ; 3.
DR SUPFAM; SSF50998; Quinoprotein alcohol dehydrogenase-like; 1.
PE 3: Inferred from homology;
KW Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000077535};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..18
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 19..934
FT /note="ER membrane protein complex subunit 1"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5008084442"
FT TRANSMEM 903..923
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 708..932
FT /note="ER membrane protein complex subunit 1 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF07774"
FT REGION 742..765
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 934 AA; 101282 MW; F6A812041A259892 CRC64;
MRFHAALALA ACLAPAAAIF EDDAYHIDFH YALLGLPKHE ATFFQKPYAG SKASLLYSVS
QNQTIGAINP KDGALVWRHN FPETHGKAHL RSGNEQDTVI SAVGDRIAAW SAADGRLVWE
TSFPGAVVED LEILEQEDGA TVNDAKDAIV LLADGTHGLK RIDGKTGRVK WTFEDTSGDT
PFQVSTSPTT VYYVSLHSPL LGGSKLRVTS LSPITGKKLD QYTLNSDAEI TSLDHILFAG
ANTAAPLLAW TDKANKVLKV NIIGTKNVAS FNTPADETIE KIRLHAPNHV NSLPHFLVEY
QTVVGHSAEV YHVDLKKNTV SKAYSLPELK NKGTFTTSTT DANVYFTRIT EDEVSVVSSV
SHGILGRWTV NGSPQLAGAS PVSGVSEVVV KAGAASAVRS AVLYSNGQWV LIRNEEVAWT
RPEFLSGAIS AVWAGLPEEE ALAQALAEES HRNLVSAYIH RVLRHADDLK YFPAWVQSLP
DRLLGSVLGK SKEVTVDDIQ QDTFGFHKLV VVATENGRLA ALDVGSRGKI MWNVDLKQFV
PELSFHSPAL KAFNGYVEVR DPELKGSLLI NSTTGGLISS DSAPAGASFA TEGQQLVSFS
LVDGVLQGFL EGRPTTEPVW TFTPTGGERI VNYVARPIND PVASIGRVLG DRRVLYKYLN
PNLVLVTAVL DTAHTASIYL LDSASGQLLY TTSHQDVDTS RWIPSTISEN WFTYSFTVDA
NAGVSSRGYQ LVVSDLYESP LPDDRGPLGA NGNASTVQPA GDGDASKPYV LTQSYQILAE
ISHMTVTQTK QGITSRELLV TVPSFSAIIG IPRSFIDPRR PIGRDPTAHE QSEGLIKYTP
LISFDPKWHL THKYEVEGVK DVITSESGIE STSLVFAYGL DIFGTRVAPS FAFDILGKGF
NKISMLITVA ALFVGVLFVA PLVRRKQINT LWTI
//
