ID   A0A178F102_TRIRU        Unreviewed;       398 AA.
AC   A0A178F102;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   RecName: Full=Chalcone synthase {ECO:0008006|Google:ProtNLM};
GN   ORFNames=A7C99_2793 {ECO:0000313|EMBL:OAL65695.1};
OS   Trichophyton rubrum (Athlete's foot fungus) (Epidermophyton rubrum).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Arthrodermataceae; Trichophyton.
OX   NCBI_TaxID=5551 {ECO:0000313|EMBL:OAL65695.1, ECO:0000313|Proteomes:UP000243015};
RN   [1] {ECO:0000313|EMBL:OAL65695.1, ECO:0000313|Proteomes:UP000243015}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CMCC(F)T1i {ECO:0000313|Proteomes:UP000243015};
RA   Zhan P., Tao Y., Liu W.;
RT   "Genome sequencing of Trichophyton rubrum CMCC(F)T1i isolated from hair.";
RL   Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the thiolase-like superfamily. Chalcone/stilbene
CC       synthases family. {ECO:0000256|ARBA:ARBA00005531,
CC       ECO:0000256|RuleBase:RU003633}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OAL65695.1}.
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DR   EMBL; LHPM01000013; OAL65695.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A178F102; -.
DR   SMR; A0A178F102; -.
DR   VEuPathDB; FungiDB:TERG_02293; -.
DR   OMA; ACVRSWG; -.
DR   OrthoDB; 883077at2759; -.
DR   Proteomes; UP000243015; Unassembled WGS sequence.
DR   GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:InterPro.
DR   GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR   Gene3D; 3.40.47.10; -; 2.
DR   InterPro; IPR012328; Chalcone/stilbene_synt_C.
DR   InterPro; IPR001099; Chalcone/stilbene_synt_N.
DR   InterPro; IPR011141; Polyketide_synthase_type-III.
DR   InterPro; IPR016039; Thiolase-like.
DR   PANTHER; PTHR11877; HYDROXYMETHYLGLUTARYL-COA SYNTHASE; 1.
DR   PANTHER; PTHR11877:SF46; TYPE III POLYKETIDE SYNTHASE A; 1.
DR   Pfam; PF02797; Chal_sti_synt_C; 1.
DR   Pfam; PF00195; Chal_sti_synt_N; 1.
DR   PIRSF; PIRSF000451; PKS_III; 1.
DR   SUPFAM; SSF53901; Thiolase-like; 2.
PE   3: Inferred from homology;
KW   Acyltransferase {ECO:0000256|RuleBase:RU003633};
KW   Reference proteome {ECO:0000313|Proteomes:UP000243015};
KW   Transferase {ECO:0000256|RuleBase:RU003633}.
FT   DOMAIN          81..227
FT                   /note="Chalcone/stilbene synthase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00195"
FT   DOMAIN          250..389
FT                   /note="Chalcone/stilbene synthase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF02797"
SQ   SEQUENCE   398 AA;  43190 MW;  D7BB5D16B230EDF6 CRC64;
     MPASRCASNP LVAPGLFIVG LGSQYPPYLL DHEKLTCFAG RFHDIRRPGL QKLLQINAST
     GIETRSSIRS YETGFACDPV PPSIADLDEL FRRDGVDLAV QACMKAMKEA GVLPEQITHT
     VSVTCTNQGN PGYDLLVNER LGLPERTSRI LLHGVGCAGG LSIMRVASQV ACGATMRGRK
     ACILVYACEL CTPNVRHDLA EAEQCTDLSK VNIAGALFSD AAAAFILCNK TALEESSASP
     IFELIEWDNA LIPDTMQHLT CYTDPYGFRS VLTKDIPTYA KGAIGPMFHK LLPSYEEQVL
     AADIHLGIDD FDWAVHPGGK ALIDGVQETM QLTEDQLQAS REIYRTRGNS SSPTILSVLD
     RLRTYEKQRG HVVAASFGPG MAIEMVMLKR CEVAGGGQ
//