ID   A0A178F1Z1_TRIRU        Unreviewed;       795 AA.
AC   A0A178F1Z1;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   22-FEB-2023, entry version 16.
DE   SubName: Full=Rho GTPase activator (Sac7) {ECO:0000313|EMBL:OAL66055.1};
GN   ORFNames=A7C99_3159 {ECO:0000313|EMBL:OAL66055.1};
OS   Trichophyton rubrum (Athlete's foot fungus) (Epidermophyton rubrum).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Arthrodermataceae; Trichophyton.
OX   NCBI_TaxID=5551 {ECO:0000313|EMBL:OAL66055.1, ECO:0000313|Proteomes:UP000243015};
RN   [1] {ECO:0000313|EMBL:OAL66055.1, ECO:0000313|Proteomes:UP000243015}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CMCC(F)T1i {ECO:0000313|Proteomes:UP000243015};
RA   Zhan P., Tao Y., Liu W.;
RT   "Genome sequencing of Trichophyton rubrum CMCC(F)T1i isolated from hair.";
RL   Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OAL66055.1}.
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DR   EMBL; LHPM01000013; OAL66055.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A178F1Z1; -.
DR   VEuPathDB; FungiDB:TERG_01847; -.
DR   Proteomes; UP000243015; Unassembled WGS sequence.
DR   GO; GO:0005096; F:GTPase activator activity; IEA:UniProt.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   CDD; cd04396; RhoGAP_fSAC7_BAG7; 1.
DR   Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR   InterPro; IPR008936; Rho_GTPase_activation_prot.
DR   InterPro; IPR000198; RhoGAP_dom.
DR   PANTHER; PTHR15228; SPERMATHECAL PHYSIOLOGY VARIANT; 1.
DR   PANTHER; PTHR15228:SF25; SPERMATHECAL PHYSIOLOGY VARIANT; 1.
DR   Pfam; PF00620; RhoGAP; 1.
DR   SMART; SM00324; RhoGAP; 1.
DR   SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR   PROSITE; PS50238; RHOGAP; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000243015}.
FT   DOMAIN          85..295
FT                   /note="Rho-GAP"
FT                   /evidence="ECO:0000259|PROSITE:PS50238"
FT   REGION          1..42
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          317..795
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..39
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        349..401
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        443..460
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        524..548
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        549..573
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        604..633
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        649..695
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        703..741
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        748..769
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   795 AA;  85091 MW;  AB2DFDAD41CC2C63 CRC64;
     MAHSQSQSQS QAQEASATST PSPAASGLVN SSTAAHSPPS KRDLASWWRQ FKRSTKKDAA
     LAPQAPSGIF GIPLNVSIKY ANVAISLTGD DGKSFIYGYV PIVVAKCGVF LKEKATDVEG
     IFRLSGSAKR IKDLQEIFNS PDRFGKGLDW TGYTVHDAAN ILRRYLNQLP EPIVPLEFYE
     RFREPLRHRH GRPDGEEAAI QVDRERGFDR EAAVIAYQQL IKELPPLNRQ LLLYILDLLT
     VFASKSDLNR MTAANLAAIF QPGMLSHPSH DMSPQDYKLS QDVLVFLIEN QDNFLFGMTG
     TAADAQTVQN IQGGMYPPPP LQKTTIRRSA SNASGGADSL RKYEALRRNM SVSSRNSNGN
     VTGPSTPNSN SKGGGLQRSN TVPSKRAPGF SPSSTFARQQ AATPPAAGLS APPQLQMTPV
     VKGSPAQDIT KVAEHPEPTT GAIDTKQPEN GATSTAEVAE TAPATEAAQI SLPVRNIEAA
     LPEEPAKATT EAAPAQPVES TKSDHPTEPA RAPQLAEPFE FTKAPEPGPS PALVPTPAPA
     PASTPSPGPD STAQPATAAQ LAPVEQSQPA QPSSPAPSAQ PAYPVSKSQR PNHIDAPLPT
     QLDPATHKPT TITPTRERKL ASLFSWTSPP SGEKRDTNKL KKKRRIPGSA SESAQSSTAS
     LPHGSQTGSD EATPTKQQQQ PTTSQPTTSS NPEDPAVADE SHVSTPKVTN PPLSPLVPVR
     SASTSQSHTS LEVNSPPHHH TSLTDRMLRP RSRTPSPNSH SLSATDQSDL EESSRGDKKD
     KRRSWRFHLG KKSDD
//