ID A0A178F6L5_TRIRU Unreviewed; 785 AA.
AC A0A178F6L5;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Heat shock protein 78 {ECO:0000313|EMBL:OAL67107.1};
GN ORFNames=A7C99_1522 {ECO:0000313|EMBL:OAL67107.1};
OS Trichophyton rubrum (Athlete's foot fungus) (Epidermophyton rubrum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Arthrodermataceae; Trichophyton.
OX NCBI_TaxID=5551 {ECO:0000313|EMBL:OAL67107.1, ECO:0000313|Proteomes:UP000243015};
RN [1] {ECO:0000313|EMBL:OAL67107.1, ECO:0000313|Proteomes:UP000243015}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CMCC(F)T1i {ECO:0000313|Proteomes:UP000243015};
RA Zhan P., Tao Y., Liu W.;
RT "Genome sequencing of Trichophyton rubrum CMCC(F)T1i isolated from hair.";
RL Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the ClpA/ClpB family.
CC {ECO:0000256|ARBA:ARBA00008675, ECO:0000256|RuleBase:RU004432}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OAL67107.1}.
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DR EMBL; LHPM01000011; OAL67107.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A178F6L5; -.
DR VEuPathDB; FungiDB:TERG_07949; -.
DR OMA; SKMMQGE; -.
DR OrthoDB; 35211at2759; -.
DR Proteomes; UP000243015; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd00009; AAA; 1.
DR CDD; cd19499; RecA-like_ClpB_Hsp104-like; 1.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR019489; Clp_ATPase_C.
DR InterPro; IPR001270; ClpA/B.
DR InterPro; IPR018368; ClpA/B_CS1.
DR InterPro; IPR028299; ClpA/B_CS2.
DR InterPro; IPR041546; ClpA/ClpB_AAA_lid.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR11638; ATP-DEPENDENT CLP PROTEASE; 1.
DR PANTHER; PTHR11638:SF18; HEAT SHOCK PROTEIN 78, MITOCHONDRIAL; 1.
DR Pfam; PF00004; AAA; 1.
DR Pfam; PF07724; AAA_2; 1.
DR Pfam; PF17871; AAA_lid_9; 1.
DR Pfam; PF10431; ClpB_D2-small; 1.
DR PRINTS; PR00300; CLPPROTEASEA.
DR SMART; SM00382; AAA; 2.
DR SMART; SM01086; ClpB_D2-small; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS00870; CLPAB_1; 1.
DR PROSITE; PS00871; CLPAB_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU004432};
KW Chaperone {ECO:0000256|RuleBase:RU004432};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU004432};
KW Reference proteome {ECO:0000313|Proteomes:UP000243015};
KW Stress response {ECO:0000313|EMBL:OAL67107.1}.
FT DOMAIN 115..259
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT DOMAIN 516..703
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT DOMAIN 688..779
FT /note="Clp ATPase C-terminal"
FT /evidence="ECO:0000259|SMART:SM01086"
FT REGION 428..447
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 328..408
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 785 AA; 86749 MW; 1529885C8155FF63 CRC64;
MSCRLVMRGS RQLFQAPRAA AHINTTARRA LYGLLPRQLS KQYVPASGFV RHYANGRPHP
PGGTHRMNLG GEPEKPALEQ FGVDLTARAK DGKLDPVIGR DAEIHRTIQI LSRRTKNNPV
LIGAAGTGKT AVLEGLAQRI VRGDVPESVK NKRVISLDLG QLIAGAKFRG DFEERLKRVL
KEVEDAQGGV ILFVDELHTL LGLGKAEGSI DASNLIKPAL ARGDLQCCGA TTLNEYRQIE
KDVALARRFQ PILVEEPTVP DTISILRGIK DKYEVHHGVR ITDGALVAAA TYSNRYITDR
FLPDKAIDLV DEAASALRLQ QESKPDAIQE LDRQIMTIQI ELESLRKEKD IASVERREKL
EELLKSKQED VGKLTEAWDK EKAELEAIKQ AKEDLERARG ELEQAQLEGN FAKAGELRYS
TIPNLEKKLP QEDDTGSTGT QGQSLLHDSV TADDIAGVVS RTTGIPVNKL MSGEVEKLIH
MEDTLRKSVR GQDEALEAVA NAVRMQRAGL SGENRPLASF MFLGPTGVGK TELCKKMAGF
LFSTETAVVR FDMSEFQEKH TVSRLIGSPA GYVGYDDAGQ LTEAVRRKPY AVLLFDEFEK
AHRDISALLL QVLDEGFLTD AQGHKIDFRN TLIVLTSNLG AEVLVSTDAS EGEDISPEMK
SAVMGIVQSS YPPEFLNRID EFILFKRLSR SALRDIVDIR VKELQARLDD RRITLSVSDE
IKDWLCEKGY DPKYGARPLN RLISKEIGNH LADKIIRGQV VSGQTATAIF NEDKTGLDIA
TEKSA
//
