ID A0A178GE46_9GAMM Unreviewed; 344 AA.
AC A0A178GE46;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=Ribosomal RNA small subunit methyltransferase C {ECO:0000256|HAMAP-Rule:MF_01862};
DE EC=2.1.1.172 {ECO:0000256|HAMAP-Rule:MF_01862};
DE AltName: Full=16S rRNA m2G1207 methyltransferase {ECO:0000256|HAMAP-Rule:MF_01862};
DE AltName: Full=rRNA (guanine-N(2)-)-methyltransferase RsmC {ECO:0000256|HAMAP-Rule:MF_01862};
GN Name=rsmC {ECO:0000256|HAMAP-Rule:MF_01862};
GN ORFNames=AY605_13065 {ECO:0000313|EMBL:OAL82225.1};
OS Acinetobacter sp. SFD.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Moraxellales; Moraxellaceae;
OC Acinetobacter.
OX NCBI_TaxID=1805635 {ECO:0000313|EMBL:OAL82225.1, ECO:0000313|Proteomes:UP000186186};
RN [1] {ECO:0000313|EMBL:OAL82225.1, ECO:0000313|Proteomes:UP000186186}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SFD {ECO:0000313|EMBL:OAL82225.1,
RC ECO:0000313|Proteomes:UP000186186};
RA Wen L., He K., Yang H.;
RL Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Specifically methylates the guanine in position 1207 of 16S
CC rRNA in the 30S particle. {ECO:0000256|HAMAP-Rule:MF_01862}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=guanosine(1207) in 16S rRNA + S-adenosyl-L-methionine = H(+) +
CC N(2)-methylguanosine(1207) in 16S rRNA + S-adenosyl-L-homocysteine;
CC Xref=Rhea:RHEA:42736, Rhea:RHEA-COMP:10213, Rhea:RHEA-COMP:10214,
CC ChEBI:CHEBI:15378, ChEBI:CHEBI:57856, ChEBI:CHEBI:59789,
CC ChEBI:CHEBI:74269, ChEBI:CHEBI:74481; EC=2.1.1.172;
CC Evidence={ECO:0000256|HAMAP-Rule:MF_01862};
CC -!- SUBUNIT: Monomer. {ECO:0000256|HAMAP-Rule:MF_01862}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_01862}.
CC -!- SIMILARITY: Belongs to the methyltransferase superfamily. RsmC family.
CC {ECO:0000256|HAMAP-Rule:MF_01862}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OAL82225.1}.
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DR EMBL; LSZJ01000018; OAL82225.1; -; Genomic_DNA.
DR RefSeq; WP_064097085.1; NZ_LSZJ01000018.1.
DR AlphaFoldDB; A0A178GE46; -.
DR STRING; 1805635.AY605_13065; -.
DR Proteomes; UP000186186; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0052914; F:16S rRNA (guanine(1207)-N(2))-methyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR CDD; cd02440; AdoMet_MTases; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 2.
DR HAMAP; MF_01862; 16SrRNA_methyltr_C; 1.
DR InterPro; IPR002052; DNA_methylase_N6_adenine_CS.
DR InterPro; IPR013675; Mtase_sm_N.
DR InterPro; IPR023543; rRNA_ssu_MeTfrase_C.
DR InterPro; IPR046977; RsmC/RlmG.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR007848; Small_mtfrase_dom.
DR PANTHER; PTHR47816; RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE C; 1.
DR PANTHER; PTHR47816:SF4; RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE C; 1.
DR Pfam; PF05175; MTS; 1.
DR Pfam; PF08468; MTS_N; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS00092; N6_MTASE; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|HAMAP-Rule:MF_01862};
KW Methyltransferase {ECO:0000256|HAMAP-Rule:MF_01862,
KW ECO:0000313|EMBL:OAL82225.1};
KW rRNA processing {ECO:0000256|HAMAP-Rule:MF_01862};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691, ECO:0000256|HAMAP-
KW Rule:MF_01862};
KW Transferase {ECO:0000256|HAMAP-Rule:MF_01862, ECO:0000313|EMBL:OAL82225.1}.
FT DOMAIN 5..156
FT /note="Methyltransferase small N-terminal"
FT /evidence="ECO:0000259|Pfam:PF08468"
FT DOMAIN 165..333
FT /note="Methyltransferase small"
FT /evidence="ECO:0000259|Pfam:PF05175"
SQ SEQUENCE 344 AA; 38310 MW; FCE0430A129BCF5F CRC64;
MDPKSEVLLR QYDFLSGRIL LINAPTDNLL AEFDASINPA VWTWNFNDFQ YFQSQQADVH
FGAEMPEAEF DQAVIFVPKS KELLNYLLHT VAAQLKPGSS IFLVGEKKGG IERAAKQLQP
FGKTLKLDSA RHCQLWQLVL DHTVEKKALA DWAQRYTVST PNDDLIICAL PGVFSQNRLD
VGTATLLPYL SQVTSGKIAD FGCGAGVISA YLAKLNPKNR IFAMDVDAFA LASTQMTFEE
NQLTPEQIEI KAVTGIEDAP LFLHAIVSNP PFHMGIETDY TASETLCKTS RRHLKSGGEL
WIVANRFLNY PTLIEQNFGR CTVKADQQGF KVLFASTQKN VKES
//
