ID A0A178K2K0_9GAMM Unreviewed; 858 AA.
AC A0A178K2K0;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=A3K86_21625 {ECO:0000313|EMBL:OAN11530.1};
OS Photobacterium jeanii.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC Photobacterium.
OX NCBI_TaxID=858640 {ECO:0000313|EMBL:OAN11530.1, ECO:0000313|Proteomes:UP000078503};
RN [1] {ECO:0000313|EMBL:OAN11530.1, ECO:0000313|Proteomes:UP000078503}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=R-40508 {ECO:0000313|EMBL:OAN11530.1,
RC ECO:0000313|Proteomes:UP000078503};
RA Li Y.;
RT "Photobacterium proteolyticum sp. nov. a protease producing bacterium
RT isolated from ocean sediments of Laizhou Bay.";
RL Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OAN11530.1}.
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DR EMBL; LVHF01000033; OAN11530.1; -; Genomic_DNA.
DR RefSeq; WP_068336494.1; NZ_PYMD01000002.1.
DR AlphaFoldDB; A0A178K2K0; -.
DR STRING; 858640.A3K86_21625; -.
DR OrthoDB; 9810730at2; -.
DR Proteomes; UP000078503; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd16922; HATPase_EvgS-ArcB-TorS-like; 1.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd17546; REC_hyHK_CKI1_RcsC-like; 2.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 6.10.340.10; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR033414; Sensor_dom.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR PANTHER; PTHR45339; HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE J; 1.
DR PANTHER; PTHR45339:SF1; HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE J; 1.
DR Pfam; PF17149; CHASE5; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF00072; Response_reg; 2.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00448; REC; 2.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF52172; CheY-like; 2.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR PROSITE; PS50885; HAMP; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 2.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022912};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:OAN11530.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553, ECO:0000256|PROSITE-
KW ProRule:PRU00169}; Protein phosphatase {ECO:0000256|ARBA:ARBA00022912};
KW Reference proteome {ECO:0000313|Proteomes:UP000078503};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 20..42
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 152..175
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 176..231
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 253..474
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT DOMAIN 492..613
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT DOMAIN 737..854
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT COILED 226..253
FT /evidence="ECO:0000256|SAM:Coils"
FT MOD_RES 546
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
FT MOD_RES 786
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 858 AA; 96380 MW; 3FFB26F59F473A49 CRC64;
MNKAHQDHEK KRYLGLAKQL LIYILLVTTV LTLMMTGGNL YLDYKSDLAN IESRLEQINQ
SSLESLTSSL WVEDREQLQL QAEGIFRLPE IHYLVIRDPD GVILQLGEEL QKYQYEQSWS
MEFTSNNRSY ELATLTVQSD LYQVYQGLID KFIVLLLYQA VQTFLIAAFI LFIVYRLIVR
HLVQMATVVS EFDDNQLPSQ VDIESRHFDD EITRLQNSYN FAVDRIKHHY EELEHAREQA
VDANNKKSEF LANMSHEIRT PMNGIIGLSS LLQGMPLKED QKEYVDMLHS SSLSLLDLIN
DILDFSKIES GQMELEHTRL NLFELNKDVE TIFLVKAAEK GLLFQCAIDK QIPPLLLGDP
TQLRQVLVNL VSNAIKFTHK GHVQLNMHFE SSTDDKVKVK FEVVDSGIGI AADKHATIFE
KFQQADGSTT RQYGGTGLGL AICQRVVDLM GSKLEVQSEE GKGSTFYFSV NFEQCQAQPR
SASNGKSMED IRVLLVDDRM MNMRITSAQL CGFGAYSMCC EDATLAAQFI DESIKQNTPF
DLILLDKIMP EIDGFVLATQ LRQRYGDQCP AMVMITAGPD ASDLKKMKSS GIKAILSRPY
QEAQLKWQVE HALGLVSEQQ SQQNVLEENI DETDALDDAV LEQHNTNNTI DGEMSAKAST
TVPIVNKEHN SDNRHLQQES IKAQPAKVQK TEAVMLAKEG STSAIPAGSH AVSNLPKSNF
AGGTTIESAE SKAPFARVLV VEDTVVNQKV AKMMLEKMGV EVTIAANGLI GVEMFDQQTF
DLILMDCQMP VMDGFEATRN IRQHEEAGKH IPIIALTANV VKEEKEKCFE AGMDDFLAKP
VNQKLLKETL FKHLNISG
//
