ID A0A178KRQ2_9GAMM Unreviewed; 406 AA.
AC A0A178KRQ2;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 24-JAN-2024, entry version 26.
DE RecName: Full=General secretion pathway protein F {ECO:0000256|ARBA:ARBA00030750};
GN ORFNames=A3K86_00835 {ECO:0000313|EMBL:OAN19212.1};
OS Photobacterium jeanii.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC Photobacterium.
OX NCBI_TaxID=858640 {ECO:0000313|EMBL:OAN19212.1, ECO:0000313|Proteomes:UP000078503};
RN [1] {ECO:0000313|EMBL:OAN19212.1, ECO:0000313|Proteomes:UP000078503}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=R-40508 {ECO:0000313|EMBL:OAN19212.1,
RC ECO:0000313|Proteomes:UP000078503};
RA Li Y.;
RT "Photobacterium proteolyticum sp. nov. a protease producing bacterium
RT isolated from ocean sediments of Laizhou Bay.";
RL Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Component of the type II secretion system inner membrane
CC complex required for the energy-dependent secretion of extracellular
CC factors such as proteases and toxins from the periplasm.
CC {ECO:0000256|ARBA:ARBA00002684}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane
CC {ECO:0000256|ARBA:ARBA00004429, ECO:0000256|RuleBase:RU003923}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004429,
CC ECO:0000256|RuleBase:RU003923}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the GSP F family.
CC {ECO:0000256|ARBA:ARBA00005745, ECO:0000256|RuleBase:RU003923}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OAN19212.1}.
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DR EMBL; LVHF01000010; OAN19212.1; -; Genomic_DNA.
DR RefSeq; WP_068326244.1; NZ_PYMD01000010.1.
DR AlphaFoldDB; A0A178KRQ2; -.
DR STRING; 858640.A3K86_00835; -.
DR OrthoDB; 9805682at2; -.
DR Proteomes; UP000078503; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015627; C:type II protein secretion system complex; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0015628; P:protein secretion by the type II secretion system; IEA:InterPro.
DR Gene3D; 1.20.81.30; Type II secretion system (T2SS), domain F; 2.
DR InterPro; IPR003004; GspF/PilC.
DR InterPro; IPR011850; T2SS_GspF.
DR InterPro; IPR001992; T2SS_GspF/T4SS_PilC_CS.
DR InterPro; IPR018076; T2SS_GspF_dom.
DR InterPro; IPR042094; T2SS_GspF_sf.
DR NCBIfam; TIGR02120; GspF; 1.
DR PANTHER; PTHR30012; GENERAL SECRETION PATHWAY PROTEIN; 1.
DR PANTHER; PTHR30012:SF0; TYPE II SECRETION SYSTEM PROTEIN F-RELATED; 1.
DR Pfam; PF00482; T2SSF; 2.
DR PRINTS; PR00812; BCTERIALGSPF.
DR PROSITE; PS00874; T2SP_F; 1.
PE 3: Inferred from homology;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000078503};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU003923};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU003923}.
FT TRANSMEM 170..193
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 224..243
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 377..398
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 72..194
FT /note="Type II secretion system protein GspF"
FT /evidence="ECO:0000259|Pfam:PF00482"
FT DOMAIN 274..396
FT /note="Type II secretion system protein GspF"
FT /evidence="ECO:0000259|Pfam:PF00482"
SQ SEQUENCE 406 AA; 45271 MW; A6EA02A9E241DCFD CRC64;
MAAFEYKAID SKGRQKKGVL EGDNARQVRQ QLREKGLMAT EVVQTTEREK KKASSSFSFR
RGIRTHDLSL ITRQLATLVQ AAMPLEECLK AVAEQCEKPR LKNMLLGVRS RVVEGYTLSD
SMAEYPHVFD QLFRAMVAAG EKSGHLDTVL NRLADYTENR QQMRSKLQQA MIYPTMLTLV
AVSVVAFLLA TVVPKIVDQF VQMGQQLPGI TEVLLIASDF VQNWGLAVLV VIVGIVMAAK
AALRKPDFRL RWDRWVLNIP VIGKVARGLN TSRFARTLSI CTSSAIPLLD GMKVASDVMT
NTWVNRQIIE ASDKVREGSS LRIALEQTKL FPPMMLHMIA SGERSGELEQ MLTRSADNQD
RDFESLVNMA LGIFEPLLIV AMAGIVMFIV IATLMPIIEL NNMVGM
//
