ID A0A178US29_ARATH Unreviewed; 806 AA.
AC A0A178US29; A0A1P8BA66;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE SubName: Full=Leucine-rich repeat protein kinase family protein {ECO:0000313|EMBL:ANM68485.1};
GN Name=MUA22.21 {ECO:0000313|EMBL:ANM68485.1};
GN Synonyms=MUA22_21 {ECO:0000313|EMBL:ANM68485.1};
GN OrderedLocusNames=At5g14210 {ECO:0000313|Araport:AT5G14210,
GN ECO:0000313|EMBL:ANM68485.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702 {ECO:0000313|EMBL:ANM68485.1, ECO:0000313|Proteomes:UP000006548};
RN [1] {ECO:0000313|EMBL:ANM68485.1, ECO:0000313|Proteomes:UP000006548}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia {ECO:0000313|Proteomes:UP000006548};
RX PubMed=11130714; DOI=10.1038/35048507;
RG Kazusa DNA Research Institute;
RG Cold Spring Harbor and Washington University in St Louis Sequencing Consortium;
RG European Union Arabidopsis Genome Sequencing Consortium;
RA Tabata S., Kaneko T., Nakamura Y., Kotani H., Kato T., Asamizu E.,
RA Miyajima N., Sasamoto S., Kimura T., Hosouchi T., Kawashima K., Kohara M.,
RA Matsumoto M., Matsuno A., Muraki A., Nakayama S., Nakazaki N., Naruo K.,
RA Okumura S., Shinpo S., Takeuchi C., Wada T., Watanabe A., Yamada M.,
RA Yasuda M., Sato S., de la Bastide M., Huang E., Spiegel L., Gnoj L.,
RA O'Shaughnessy A., Preston R., Habermann K., Murray J., Johnson D.,
RA Rohlfing T., Nelson J., Stoneking T., Pepin K., Spieth J., Sekhon M.,
RA Armstrong J., Becker M., Belter E., Cordum H., Cordes M., Courtney L.,
RA Courtney W., Dante M., Du H., Edwards J., Fryman J., Haakensen B.,
RA Lamar E., Latreille P., Leonard S., Meyer R., Mulvaney E., Ozersky P.,
RA Riley A., Strowmatt C., Wagner-McPherson C., Wollam A., Yoakum M., Bell M.,
RA Dedhia N., Parnell L., Shah R., Rodriguez M., See L.H., Vil D., Baker J.,
RA Kirchoff K., Toth K., King L., Bahret A., Miller B., Marra M.,
RA Martienssen R., McCombie W.R., Wilson R.K., Murphy G., Bancroft I.,
RA Volckaert G., Wambutt R., Dusterhoft A., Stiekema W., Pohl T., Entian K.D.,
RA Terryn N., Hartley N., Bent E., Johnson S., Langham S.A., McCullagh B.,
RA Robben J., Grymonprez B., Zimmermann W., Ramsperger U., Wedler H.,
RA Balke K., Wedler E., Peters S., van Staveren M., Dirkse W., Mooijman P.,
RA Lankhorst R.K., Weitzenegger T., Bothe G., Rose M., Hauf J., Berneiser S.,
RA Hempel S., Feldpausch M., Lamberth S., Villarroel R., Gielen J.,
RA Ardiles W., Bents O., Lemcke K., Kolesov G., Mayer K., Rudd S., Schoof H.,
RA Schueller C., Zaccaria P., Mewes H.W., Bevan M., Fransz P.;
RT "Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana.";
RL Nature 408:823-826(2000).
RN [2] {ECO:0000313|Proteomes:UP000006548}
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia {ECO:0000313|Proteomes:UP000006548};
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
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DR EMBL; CP002688; ANM68485.1; -; Genomic_DNA.
DR RefSeq; NP_001330239.1; NM_001343322.1.
DR AlphaFoldDB; A0A178US29; -.
DR SMR; A0A178US29; -.
DR IntAct; A0A178US29; 23.
DR STRING; 3702.A0A178US29; -.
DR ProteomicsDB; 195317; -.
DR EnsemblPlants; AT5G14210.2; AT5G14210.2; AT5G14210.
DR GeneID; 831271; -.
DR Gramene; AT5G14210.2; AT5G14210.2; AT5G14210.
DR KEGG; ath:AT5G14210; -.
DR Araport; AT5G14210; -.
DR TAIR; AT5G14210; -.
DR InParanoid; A0A178US29; -.
DR OMA; ISITVKC; -.
DR OrthoDB; 3686501at2759; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; A0A178US29; baseline and differential.
DR GO; GO:0016020; C:membrane; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR GO; GO:0033612; F:receptor serine/threonine kinase binding; IBA:GO_Central.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 2.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR001245; Ser-Thr/Tyr_kinase_cat_dom.
DR PANTHER; PTHR48005; LEUCINE RICH REPEAT KINASE 2; 1.
DR PANTHER; PTHR48005:SF94; LEUCINE-RICH REPEAT RECEPTOR-LIKE SERINE_THREONINE-PROTEIN KINASE; 1.
DR Pfam; PF00560; LRR_1; 1.
DR Pfam; PF13855; LRR_8; 2.
DR Pfam; PF07714; PK_Tyr_Ser-Thr; 1.
DR PRINTS; PR00019; LEURICHRPT.
DR SMART; SM00369; LRR_TYP; 5.
DR SUPFAM; SSF52058; L domain-like; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS51450; LRR; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
PE 1: Evidence at protein level;
KW Kinase {ECO:0000313|EMBL:ANM68485.1};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Proteomics identification {ECO:0007829|PeptideAtlas:A0A178US29,
KW ECO:0007829|ProteomicsDB:A0A178US29};
KW Reference proteome {ECO:0000313|Proteomes:UP000006548};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP};
KW Transferase {ECO:0000313|EMBL:ANM68485.1};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..23
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 24..806
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5030024034"
FT TRANSMEM 394..420
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 490..789
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
SQ SEQUENCE 806 AA; 88931 MW; BCFBDCF2E6B27D59 CRC64;
MEQLKVLPLL FLSWVMFLQS THQLPNSQTQ VLYQLRKHLE FPKALESWGN YYGDLCQIPA
TAHMSITCQG NSITELKVMG DKLFKPFGMF DGSSLPNHTL SEAFIIDSFV TTLTRLTSLR
VLSLVSLGIY GEFPGKIHRL NSLEYLDLSS NFLFGSVPPD ISRLVMLQSL MLDGNYFNGS
VPDTLDSLTN LTVLSLKNNR FKGPFPSSIC RIGRLTNLAL SHNEISGKLP DLSKLSHLHM
LDLRENHLDS ELPVMPIRLV TVLLSKNSFS GEIPRRFGGL SQLQHLDLSF NHLTGTPSRF
LFSLPNISYL DLASNKLSGK LPLNLTCGGK LGFVDLSNNR LIGTPPRCLA GASGERVVKL
GGNCLSIIGS HDQHQEFLCE EAETEGKQFQ GRKVGILIAV IGGAVLVLVF FVLVILLLLC
TNRCSSCCSR EKSVPQTRLK VVTDNSHTSL SSEVLASARL ISQTAKLGAQ GVPSCRSFSF
EDLKEATDDF DSSRFLGEGS LGKLYRGTLE NGSSIAIRCL VLSRKFSSQS IRGHLDWMAK
LNHPHLLGFL GHCTQTSGEH DPVATILYLV YEYMPNGSYR THLSGQSFGI CSKLNVILNL
SVLGKSLLLE YCLFVESFSE KILTWPDRLA ILIEIAKAVH FLHTGVMPGS FNNQLKTNNI
LLDEHKIAKL SDYGVSAIIE ENEKLETKSE THKSKKKAKR EDDVYNFGFI LLESLIGPVP
TTKGEAFLLN EMTSFGSQDG RQKIVSPTVL TTSSQESLSI AISIANKCVL LEPSARPSFE
DVLWNLQYAA QMQSAADAER KSDTSS
//
