ID A0A178XGC2_SINSA Unreviewed; 548 AA.
AC A0A178XGC2;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Thiamine pyrophosphate-binding protein {ECO:0000313|EMBL:OAP34284.1};
GN ORFNames=ATB98_23505 {ECO:0000313|EMBL:OAP34284.1};
OS Sinorhizobium saheli.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Rhizobiaceae; Sinorhizobium/Ensifer group; Sinorhizobium.
OX NCBI_TaxID=36856 {ECO:0000313|EMBL:OAP34284.1, ECO:0000313|Proteomes:UP000078507};
RN [1] {ECO:0000313|EMBL:OAP34284.1, ECO:0000313|Proteomes:UP000078507}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LMG 7837 {ECO:0000313|EMBL:OAP34284.1,
RC ECO:0000313|Proteomes:UP000078507};
RA Yan H., Chen W.;
RT "Ensifer anhuiense sp. nov., an effective nitrogen fixation bacterium with
RT Glycine soja.";
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the TPP enzyme family.
CC {ECO:0000256|ARBA:ARBA00007812, ECO:0000256|RuleBase:RU362132}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OAP34284.1}.
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DR EMBL; LNQB01000102; OAP34284.1; -; Genomic_DNA.
DR RefSeq; WP_066879649.1; NZ_WITB01000081.1.
DR AlphaFoldDB; A0A178XGC2; -.
DR STRING; 36856.ATB98_23505; -.
DR OrthoDB; 4494979at2; -.
DR Proteomes; UP000078507; Unassembled WGS sequence.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR GO; GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
DR CDD; cd00568; TPP_enzymes; 1.
DR CDD; cd07035; TPP_PYR_POX_like; 1.
DR Gene3D; 3.40.50.970; -; 2.
DR Gene3D; 3.40.50.1220; TPP-binding domain; 1.
DR InterPro; IPR029035; DHS-like_NAD/FAD-binding_dom.
DR InterPro; IPR029061; THDP-binding.
DR InterPro; IPR012000; Thiamin_PyroP_enz_cen_dom.
DR InterPro; IPR012001; Thiamin_PyroP_enz_TPP-bd_dom.
DR InterPro; IPR000399; TPP-bd_CS.
DR InterPro; IPR045229; TPP_enz.
DR InterPro; IPR011766; TPP_enzyme_TPP-bd.
DR PANTHER; PTHR18968:SF120; ACETOLACTATE SYNTHASE LARGE SUBUNIT; 1.
DR PANTHER; PTHR18968; THIAMINE PYROPHOSPHATE ENZYMES; 1.
DR Pfam; PF02775; TPP_enzyme_C; 1.
DR Pfam; PF00205; TPP_enzyme_M; 1.
DR Pfam; PF02776; TPP_enzyme_N; 1.
DR SUPFAM; SSF52467; DHS-like NAD/FAD-binding domain; 1.
DR SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 2.
DR PROSITE; PS00187; TPP_ENZYMES; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000078507};
KW Thiamine pyrophosphate {ECO:0000256|RuleBase:RU362132}.
FT DOMAIN 3..113
FT /note="Thiamine pyrophosphate enzyme N-terminal TPP-
FT binding"
FT /evidence="ECO:0000259|Pfam:PF02776"
FT DOMAIN 187..325
FT /note="Thiamine pyrophosphate enzyme central"
FT /evidence="ECO:0000259|Pfam:PF00205"
FT DOMAIN 383..529
FT /note="Thiamine pyrophosphate enzyme TPP-binding"
FT /evidence="ECO:0000259|Pfam:PF02775"
SQ SEQUENCE 548 AA; 59345 MW; 76BE9150F0081876 CRC64;
MKTGGQLVVE AFVANGVKRV SCVPGESYLA VLDALHDTDI DVVVCRQEGG AAMMADAWGR
LSGAPGICMV TRGPGATNAS AGLHVARQDS VPMILFIGQV QRDAREREAF QEIEYRRAFT
EVAKWVGEID DAARIPEFVT RAFAVATSGR PGPVVLTLPE DMLTERAEPP AARAYQPVES
HPGPAQIARL AELLAAARRP IAVLGGTRWS PESVAGFQAF AERWHLPVGC SFRRQMLFDH
LNPNYAGDVG IGINPALASE IRDADLVLLV GGRFSEMPSS GYTLIDVPYP RQTLVHIHPD
PTELGRVYRP DLAIAASPRD FVAALAGIAP AGEPAWSART AAMHAAYRQW STPPERGPGD
VQMGPIMNWL EANTAPDTIF TNGAGNYATW LHRFHRFRRY GTQAAPASGS MGYGLPAAVA
AKHLHPDREV ICFAGDGCFL MHGQEFATAV RYELPIIVLV INNNIYGTIR MHQEREYPGR
VSATDLTNPD FAALARAYGG HGETVARTEE FAEAFLRARA SGKPTIIEVK LDPEAITPTR
TLTEIRNG
//
