ID A0A178Z5H7_9EURO Unreviewed; 1089 AA.
AC A0A178Z5H7;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=Rad4 beta-hairpin domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=AYL99_11164 {ECO:0000313|EMBL:OAP54716.1};
OS Fonsecaea erecta.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae; Fonsecaea.
OX NCBI_TaxID=1367422 {ECO:0000313|EMBL:OAP54716.1, ECO:0000313|Proteomes:UP000078343};
RN [1] {ECO:0000313|EMBL:OAP54716.1, ECO:0000313|Proteomes:UP000078343}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 125763 {ECO:0000313|EMBL:OAP54716.1,
RC ECO:0000313|Proteomes:UP000078343};
RA Weiss V.A., Vicente V.A., Raittz R.T., Moreno L.F., De Souza E.M.,
RA Pedrosa F.O., Steffens M.B., Faoro H., Tadra-Sfeir M.Z., Najafzadeh M.J.,
RA Felipe M.S., Teixeira M., Sun J., Xi L., Gomes R., De Azevedo C.M.,
RA Salgado C.G., Da Silva M.B., Nascimento M.F., Queiroz-Telles F.,
RA Attili D.S., Gorbushina A.;
RT "Draft genome of Fonsecaea erecta CBS 125763.";
RL Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the XPC family. {ECO:0000256|ARBA:ARBA00009525}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OAP54716.1}.
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DR EMBL; LVYI01000013; OAP54716.1; -; Genomic_DNA.
DR RefSeq; XP_018688083.1; XM_018842670.1.
DR AlphaFoldDB; A0A178Z5H7; -.
DR STRING; 1367422.A0A178Z5H7; -.
DR GeneID; 30015332; -.
DR OrthoDB; 181129at2759; -.
DR Proteomes; UP000078343; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003684; F:damaged DNA binding; IEA:InterPro.
DR GO; GO:0006289; P:nucleotide-excision repair; IEA:InterPro.
DR Gene3D; 2.20.20.110; Rad4, beta-hairpin domain BHD1; 1.
DR Gene3D; 3.30.60.290; Rad4, beta-hairpin domain BHD2; 1.
DR Gene3D; 3.30.70.2460; Rad4, beta-hairpin domain BHD3; 1.
DR Gene3D; 3.90.260.10; Transglutaminase-like; 1.
DR InterPro; IPR018327; BHD_2.
DR InterPro; IPR004583; DNA_repair_Rad4.
DR InterPro; IPR038765; Papain-like_cys_pep_sf.
DR InterPro; IPR018325; Rad4/PNGase_transGLS-fold.
DR InterPro; IPR018326; Rad4_beta-hairpin_dom1.
DR InterPro; IPR018328; Rad4_beta-hairpin_dom3.
DR InterPro; IPR042488; Rad4_BHD3_sf.
DR InterPro; IPR036985; Transglutaminase-like_sf.
DR PANTHER; PTHR12135:SF3; DNA REPAIR PROTEIN RAD4; 1.
DR PANTHER; PTHR12135; DNA REPAIR PROTEIN XP-C / RAD4; 1.
DR Pfam; PF10403; BHD_1; 1.
DR Pfam; PF10404; BHD_2; 1.
DR Pfam; PF10405; BHD_3; 1.
DR Pfam; PF03835; Rad4; 1.
DR SMART; SM01030; BHD_1; 1.
DR SMART; SM01031; BHD_2; 1.
DR SMART; SM01032; BHD_3; 1.
DR SUPFAM; SSF54001; Cysteine proteinases; 1.
PE 3: Inferred from homology;
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000078343}.
FT DOMAIN 480..538
FT /note="Rad4 beta-hairpin"
FT /evidence="ECO:0000259|SMART:SM01030"
FT DOMAIN 540..603
FT /note="Rad4 beta-hairpin"
FT /evidence="ECO:0000259|SMART:SM01031"
FT DOMAIN 610..684
FT /note="Rad4 beta-hairpin"
FT /evidence="ECO:0000259|SMART:SM01032"
FT REGION 1..67
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 723..759
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 823..899
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 920..1089
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 51..67
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 998..1033
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1034..1048
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1089 AA; 120487 MW; C980A4532D60D774 CRC64;
MPRRKGQPTA RATRTTRRSA RQRKEPQDDI PEIYGDMLAE AIAEEQASAS NSRASKRRKM
SEEPSTKIEL DFDLFGSAAN VHDGEETASA DDAPPKLQPV VFDDFEISDE SDAEFEDVDL
EPATNDVAEG RPLEQKTLEL DLSKTSTPRR AIQRRMPVSL AERKLRLDVH KAHLVLLLAH
LKCRNRWCNS EFVHSILKPL VSRKLISLLH VDESKPQFQR SHSFTKGIEE VCALWRQQWK
ITARGMKRAH WREDVDAVKE SEDAEDLIDF DDFKAAAISR SGSRDLGAQL FCALLRSVAV
DARLVCSLQV LPFSGIAKGQ TPEKPKPQYI YAPAQDYGSA SHDGRVNMRP AGAPDPKRKR
IVESPFPIFW VEVFSPSVQT WIPLDPLVRN TINKPKTGFE PPASDQLNSM IYVVAFEDDE
SARDVTRRYT QWYNAKTRKQ RVESTKGGEK WWEVTMSVFE KPFSETRDEI EDATLLKRAE
SEPMPKNIQD FRGHPVYVLE RHLRLNEVIH PRHEVGKVST GPLKSAKLES VFRRRDVHVC
RTADAWYRRG RDVNQGEQPL KRVVPKRQRN QDVAMAEDLE NEDEASEGMA LYAEYQTSVY
EPPPVVDEKI PRNAYGNLDV YVPSMIPAGA VHIRHPLASA AARVLGIDYA EAVTGFQFKG
RQGTAVIDGV VVSMNMTNAM INVIEGLESQ ASEEIQEART KIILAMWKKW LTALRVHEHV
HRHYGNQKHG TGDKGNDDDD DDDAEEDTMH RDEEGGGGFM LDQAELDQSE ENANSVPLTT
PNLKPLGQLL PAEVVHQDVI VIRSPNKLKQ LPLSDLLRSH DRVTEETPHE TSDAGGGFIS
EDGMVDQSPP HREGHEHAPS VRQNLANDEG GGFIPDEAED DQGGGFLPED EDGDGEPHAR
FITAHDGWIT NTEDTMGMLS SETEHASTKE RLDSTSASAG AGAGSGAENA TAAGAGDSSA
KPRSISTAGG RGLSRSGKED PATSTTRSRH IPDTDMVAPS DQSPSRPMNN TATLEPDHPF
SGSGQTTTTD QGDGGDETGD RFEAAHGPEL QRSESGTTPA SVAGSLLSHD PEDDDAEPEW
LLSSLGEID
//
