ID   A0A178ZEW0_9EURO        Unreviewed;       777 AA.
AC   A0A178ZEW0;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   22-FEB-2023, entry version 20.
DE   RecName: Full=Cullin family profile domain-containing protein {ECO:0000259|PROSITE:PS50069};
GN   ORFNames=AYL99_07414 {ECO:0000313|EMBL:OAP58324.1};
OS   Fonsecaea erecta.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae; Fonsecaea.
OX   NCBI_TaxID=1367422 {ECO:0000313|EMBL:OAP58324.1, ECO:0000313|Proteomes:UP000078343};
RN   [1] {ECO:0000313|EMBL:OAP58324.1, ECO:0000313|Proteomes:UP000078343}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 125763 {ECO:0000313|EMBL:OAP58324.1,
RC   ECO:0000313|Proteomes:UP000078343};
RA   Weiss V.A., Vicente V.A., Raittz R.T., Moreno L.F., De Souza E.M.,
RA   Pedrosa F.O., Steffens M.B., Faoro H., Tadra-Sfeir M.Z., Najafzadeh M.J.,
RA   Felipe M.S., Teixeira M., Sun J., Xi L., Gomes R., De Azevedo C.M.,
RA   Salgado C.G., Da Silva M.B., Nascimento M.F., Queiroz-Telles F.,
RA   Attili D.S., Gorbushina A.;
RT   "Draft genome of Fonsecaea erecta CBS 125763.";
RL   Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the cullin family.
CC       {ECO:0000256|ARBA:ARBA00006019, ECO:0000256|PROSITE-ProRule:PRU00330,
CC       ECO:0000256|RuleBase:RU003829}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OAP58324.1}.
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DR   EMBL; LVYI01000006; OAP58324.1; -; Genomic_DNA.
DR   RefSeq; XP_018691691.1; XM_018838923.1.
DR   AlphaFoldDB; A0A178ZEW0; -.
DR   STRING; 1367422.A0A178ZEW0; -.
DR   GeneID; 30011582; -.
DR   OrthoDB; 5474206at2759; -.
DR   Proteomes; UP000078343; Unassembled WGS sequence.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
DR   Gene3D; 1.20.1310.10; Cullin Repeats; 4.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR045093; Cullin.
DR   InterPro; IPR016158; Cullin_homology.
DR   InterPro; IPR036317; Cullin_homology_sf.
DR   InterPro; IPR001373; Cullin_N.
DR   InterPro; IPR019559; Cullin_neddylation_domain.
DR   InterPro; IPR016159; Cullin_repeat-like_dom_sf.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR11932; CULLIN; 1.
DR   PANTHER; PTHR11932:SF169; CULLIN-1; 1.
DR   Pfam; PF00888; Cullin; 1.
DR   Pfam; PF10557; Cullin_Nedd8; 1.
DR   SMART; SM00182; CULLIN; 1.
DR   SMART; SM00884; Cullin_Nedd8; 1.
DR   SUPFAM; SSF75632; Cullin homology domain; 1.
DR   SUPFAM; SSF74788; Cullin repeat-like; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS50069; CULLIN_2; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000078343}.
FT   DOMAIN          416..652
FT                   /note="Cullin family profile"
FT                   /evidence="ECO:0000259|PROSITE:PS50069"
SQ   SEQUENCE   777 AA;  89707 MW;  E13EF45D22E446EB CRC64;
     MTTTTAGTAS NPAMRARDDL DSTWAYLEKN VNNVMTKLQE GLDMKTYMGV YTAVHNFCTS
     QKAATSQSQG GSPGTLTPSH RGAHLLGEEL YTLLGKYLTE HLRDVLVSSE SHTDEALLAF
     YIREWKRYTD AAKYNNHLFR YLNRHWVKRE IDEGKKNVYD VYTLHLVKWK DDFFKAVEGK
     VMDAVLRLVE KQRNGETIDQ MQIKAIVDSF VSLGLDELDS SKPTLDVYRL YFERPFIAAT
     KEYYVNESRR FVAENSVVEY MKKAEARLEE ERERVGLYLH PDIMKKLMET CNEALISAHS
     VLLRDEFQVL LDNERTEDLA RMYKLLSRIK DGLDPLRTRF EIHVRKAGTA AVEKVAAQGD
     NFEPKVYVDA LLEIHGKYQQ LVNVAFTGES EFVRSLDNAC QEFVNHNQIC KNNSTRSPEL
     LAKYADQLLK KGAKAADESE LEELLVQIMV VFKYIEDKDV FQKFYSRMLA KRLVHTSSVS
     DDAETSMISK LKEACGYEYT NKLQRMFQDV QISKDLNTAY KDWHDKILED SDEKRTVDST
     FQILGTGFWP LNAPNTPFAP PSEINKAIES FTRFYDQKHN GRKLTWLWQL CKGEIRANYI
     KSQKVQYTFQ VSTYQMAILL LFNDSDKLDY SEIKELTKLT DETIEPAIGI LCKARVLNSS
     PEDGKPTAGT SYSLNYNFKN KKVKINLNIT VKSEQKVESE DTHKTIEEDR KLLLQAVIVR
     IMKGRKKLKH VHLVEEVINQ VRNRFPPKIS DIKKNIDALM EKDYIERLDN DELAYIA
//