ID A0A179D2L9_9BACT Unreviewed; 591 AA.
AC A0A179D2L9;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Chloride channel protein {ECO:0000313|EMBL:OAQ19959.1};
GN ORFNames=TDIS_1958 {ECO:0000313|EMBL:OAQ19959.1};
OS Thermosulfurimonas dismutans.
OC Bacteria; Thermodesulfobacteriota; Thermodesulfobacteria;
OC Thermodesulfobacteriales; Thermodesulfobacteriaceae; Thermosulfurimonas.
OX NCBI_TaxID=999894 {ECO:0000313|EMBL:OAQ19959.1, ECO:0000313|Proteomes:UP000078390};
RN [1] {ECO:0000313|EMBL:OAQ19959.1, ECO:0000313|Proteomes:UP000078390}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=S95 {ECO:0000313|EMBL:OAQ19959.1,
RC ECO:0000313|Proteomes:UP000078390};
RA Mardanov A.V., Beletsky A.V., Kadnikov V.V., Slobodkin A.I., Ravin N.V.;
RT "Genome analysis of Thermosulfurimonas dismutans, the first thermophilic
RT sulfur-disproportionating bacterium of the phylum Thermodesulfobacteria.";
RL Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OAQ19959.1}.
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DR EMBL; LWLG01000019; OAQ19959.1; -; Genomic_DNA.
DR RefSeq; WP_068671696.1; NZ_LWLG01000019.1.
DR AlphaFoldDB; A0A179D2L9; -.
DR STRING; 999894.TDIS_1958; -.
DR OrthoDB; 9767361at2; -.
DR Proteomes; UP000078390; Unassembled WGS sequence.
DR GO; GO:0034707; C:chloride channel complex; IEA:UniProtKB-KW.
DR GO; GO:0005247; F:voltage-gated chloride channel activity; IEA:InterPro.
DR CDD; cd04613; CBS_pair_voltage-gated_CLC_bac; 1.
DR CDD; cd00400; Voltage_gated_ClC; 1.
DR Gene3D; 3.10.580.10; CBS-domain; 1.
DR Gene3D; 1.10.3080.10; Clc chloride channel; 1.
DR InterPro; IPR000644; CBS_dom.
DR InterPro; IPR046342; CBS_dom_sf.
DR InterPro; IPR014743; Cl-channel_core.
DR InterPro; IPR001807; Cl-channel_volt-gated.
DR PANTHER; PTHR43427; CHLORIDE CHANNEL PROTEIN CLC-E; 1.
DR PANTHER; PTHR43427:SF6; CHLORIDE CHANNEL PROTEIN CLC-E; 1.
DR Pfam; PF00571; CBS; 2.
DR Pfam; PF00654; Voltage_CLC; 1.
DR PRINTS; PR00762; CLCHANNEL.
DR SMART; SM00116; CBS; 2.
DR SUPFAM; SSF54631; CBS-domain pair; 1.
DR SUPFAM; SSF81340; Clc chloride channel; 1.
DR PROSITE; PS51371; CBS; 2.
PE 4: Predicted;
KW CBS domain {ECO:0000256|PROSITE-ProRule:PRU00703};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..30
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 63..87
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 161..179
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 199..218
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 238..259
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 279..302
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 314..333
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 394..414
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 455..515
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
FT DOMAIN 522..580
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
SQ SEQUENCE 591 AA; 64686 MW; 41E55A5102BE6D4C CRC64;
MKRKQARLLL DAVFLGLVGA IVARLFSLMV DFSQEFFLGK IALYHPPGLP NEGGLPQEVV
GPYGLALIPL VTTIGGFLSG LLVYLLAPEA RGHGTEAAIR AFHFLEGYIR ARVPWVKMFA
SAITLGSGGS AGREGPASQI GAGIGSLYGT LFRRSSSERR LLLLMGMSGA LSAIFRSPMG
TAFFAVEVLY SQIEFETQAL IYCIFSAGVA YLVSGFVVGW EPLFRVPEDL SITSPEQYLG
FLVLGVLAGI VGTIAPLVFH YTQRLFERLP LPFYLRSAFG GLLLGLMGLA LPQVLGIGYG
WLQKAIDGEL PGKLMLLLCL AKILAFSLTI GSGGSGGDFA PSLFVGGMLG GFVAYLFNQP
PAPYVVIGMA SVFGAAARAP MANIFIVLEI TGAFALMPAT TLSVMLAYIV QTALSSPLPV
KSLYDSQVPN RVHSPAHRGE FFTDILADIK VKDIFQPEKV WAVIPEDMTL RQFVKLFGRT
EQQYFPVVDA EGRLSGIFSI NDVRPYLLNE DLWDLLIIKD IARRDVITTH PEEDINTVLR
KFTIRNIDQL PVVKTEDPRI FLGMISRREV INFYNQQLEK MRRAENLIYV V
//
