GenomeNet

Database: UniProt
Entry: A0A179D4U5_9BACT
LinkDB: A0A179D4U5_9BACT
Original site: A0A179D4U5_9BACT 
ID   A0A179D4U5_9BACT        Unreviewed;       448 AA.
AC   A0A179D4U5;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   13-FEB-2019, entry version 21.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS01081161};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=TDIS_1100 {ECO:0000313|EMBL:OAQ20811.1};
OS   Thermosulfurimonas dismutans.
OC   Bacteria; Thermodesulfobacteria; Thermodesulfobacteriales;
OC   Thermodesulfobacteriaceae; Thermosulfurimonas.
OX   NCBI_TaxID=999894 {ECO:0000313|EMBL:OAQ20811.1, ECO:0000313|Proteomes:UP000078390};
RN   [1] {ECO:0000313|EMBL:OAQ20811.1, ECO:0000313|Proteomes:UP000078390}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=S95 {ECO:0000313|EMBL:OAQ20811.1,
RC   ECO:0000313|Proteomes:UP000078390};
RA   Mardanov A.V., Beletsky A.V., Kadnikov V.V., Slobodkin A.I.,
RA   Ravin N.V.;
RT   "Genome analysis of Thermosulfurimonas dismutans, the first
RT   thermophilic sulfur-disproportionating bacterium of the phylum
RT   Thermodesulfobacteria.";
RL   Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756121}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS01082709}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:OAQ20811.1}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   EMBL; LWLG01000006; OAQ20811.1; -; Genomic_DNA.
DR   RefSeq; WP_068670136.1; NZ_LWLG01000006.1.
DR   EnsemblBacteria; OAQ20811; OAQ20811; TDIS_1100.
DR   BioCyc; GCF_001652585:TDIS_RS05455-MONOMER; -.
DR   Proteomes; UP000078390; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   Gene3D; 3.30.300.180; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR038454; DnaA_N_sf.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756129};
KW   Complete proteome {ECO:0000313|Proteomes:UP000078390};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS01082702};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00756116};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS01082706};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756117};
KW   Reference proteome {ECO:0000313|Proteomes:UP000078390}.
FT   DOMAIN      128    262       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      339    407       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     136    143       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   448 AA;  51929 MW;  4C0A1C1A31983333 CRC64;
     MSELWLKIKD FLKERLPEPV FKVWIEPLSG HCQDGKLVVS VPNEFTREWL IENYLSLFKE
     ALSLWGQGLS LAFVVEEARP PLQQDLPYEP TRVLGRKFST RYTFEEFVVG DCNRLAYKVF
     LKMAENPRGH IIYLTAESGL GKSHLSQAVG NALVSRKNTF RVCYLTARDF TSQLVRALKS
     GQMENFKERV WRNCDVLMLE EVHHIPARDF TQGELALALD YLYEEEKAVV FTSTRKPHEL
     SHLDSSLRSR LSAGMIVRIN PPDYETRKNI IRRKSRNQGQ EFPEEVVEYL ARHLRGDIRQ
     IESAVVGLIA RASILRESVN LALARELVSE IMPPEGHDLA SVVIELVCRN FKVSREDLVS
     RSRKKRISQS RQVAMFLLRK FTKESLSSIG QRFNRDHATV VYALQSVEKR LSSSPSFRYQ
     IEYLEREITE RFGVTEKECR FPKRLEKS
//
DBGET integrated database retrieval system