ID A0A179EPK2_ENTTH Unreviewed; 273 AA.
AC A0A179EPK2;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE RecName: Full=Pur operon repressor {ECO:0000256|ARBA:ARBA00018449};
GN Name=purR3 {ECO:0000313|EMBL:GEK37402.1};
GN ORFNames=A6E74_09870 {ECO:0000313|EMBL:OAQ55161.1}, CK496_11780
GN {ECO:0000313|EMBL:ASZ08528.1}, ETH01_16890
GN {ECO:0000313|EMBL:GEK37402.1};
OS Enterococcus thailandicus.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
OC Enterococcus.
OX NCBI_TaxID=417368 {ECO:0000313|EMBL:OAQ55161.1, ECO:0000313|Proteomes:UP000078516};
RN [1] {ECO:0000313|EMBL:OAQ55161.1, ECO:0000313|Proteomes:UP000078516}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=F0711D 46 {ECO:0000313|EMBL:OAQ55161.1,
RC ECO:0000313|Proteomes:UP000078516};
RA Beukers A.G., Zaheer R., Goji N., Cook S.R., Amoako K., Chaves A.V.,
RA Ward M.P., Mcallister T.A.;
RT "Draft genome of an Enterococcus thailandicus strain isolated from bovine
RT feces.";
RL Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ASZ08528.1, ECO:0000313|Proteomes:UP000217197}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=a523 {ECO:0000313|Proteomes:UP000217197}, and A523
RC {ECO:0000313|EMBL:ASZ08528.1};
RA Ybazeta G., Douglas L., Graham J., Fraleigh N., Murad Y., Perez J.,
RA Diaz-Mitoma F., Nokhbeh R.;
RT "Whole genome sequencing and hybrid de novo assembly of Enterococcus
RT thailandicus a523.";
RL Submitted (AUG-2017) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:GEK37402.1, ECO:0000313|Proteomes:UP000321361}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NBRC 101867 {ECO:0000313|EMBL:GEK37402.1,
RC ECO:0000313|Proteomes:UP000321361};
RA Hosoyama A., Uohara A., Ohji S., Ichikawa N.;
RT "Whole genome shotgun sequence of Enterococcus thailandicus NBRC 101867.";
RL Submitted (JUL-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the purine/pyrimidine phosphoribosyltransferase
CC family. {ECO:0000256|ARBA:ARBA00008391}.
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DR EMBL; CP023074; ASZ08528.1; -; Genomic_DNA.
DR EMBL; BJUG01000008; GEK37402.1; -; Genomic_DNA.
DR EMBL; LWMN01000015; OAQ55161.1; -; Genomic_DNA.
DR RefSeq; WP_067484655.1; NZ_LWMN01000015.1.
DR AlphaFoldDB; A0A179EPK2; -.
DR GeneID; 77488316; -.
DR KEGG; eth:CK496_11780; -.
DR PATRIC; fig|417368.6.peg.474; -.
DR OrthoDB; 4213751at2; -.
DR Proteomes; UP000078516; Unassembled WGS sequence.
DR Proteomes; UP000217197; Chromosome.
DR Proteomes; UP000321361; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0045892; P:negative regulation of DNA-templated transcription; IEA:InterPro.
DR GO; GO:0045982; P:negative regulation of purine nucleobase metabolic process; IEA:InterPro.
DR CDD; cd06223; PRTases_typeI; 1.
DR Gene3D; 3.40.50.2020; -; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR000836; PRibTrfase_dom.
DR InterPro; IPR029057; PRTase-like.
DR InterPro; IPR015265; PuR_N.
DR InterPro; IPR010078; PurR_Bsub.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR NCBIfam; TIGR01743; purR_Bsub; 1.
DR PANTHER; PTHR43864; HYPOXANTHINE/GUANINE PHOSPHORIBOSYLTRANSFERASE; 1.
DR PANTHER; PTHR43864:SF2; PUR OPERON REPRESSOR; 1.
DR Pfam; PF00156; Pribosyltran; 1.
DR Pfam; PF09182; PuR_N; 1.
DR SUPFAM; SSF53271; PRTase-like; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000078516};
KW Repressor {ECO:0000256|ARBA:ARBA00022491}.
FT DOMAIN 4..73
FT /note="Bacterial purine repressor N-terminal"
FT /evidence="ECO:0000259|Pfam:PF09182"
FT DOMAIN 108..248
FT /note="Phosphoribosyltransferase"
FT /evidence="ECO:0000259|Pfam:PF00156"
SQ SEQUENCE 273 AA; 30453 MW; 78C42AFE019D3BAE CRC64;
MKVRRSERLV DMTQYLLDHP HELISLTSFA ERYESAKSSI SEDLAIIKKT FKERGYGTLE
TIPGAAGGVL FIPEIPYEEA KKYIESLAER LSEQDRLLPG GYVYLSDLLG EPELLRQVGK
IIASKYLGEK IDAVMTVATK GVPIAQAVSY YLNAPFVIVR RDSKITEGST VSVNYVSGSS
ERIEKMELSK RSLKRGSRVL VVDDFMKGGG TVNGMKSLIE EFESELVGIT VFAESKFHGH
RAIDDYTSLL YVKDVDTKTK NITVVPGNYF SEE
//
