ID A0A179EVH5_METCM Unreviewed; 346 AA.
AC A0A179EVH5;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2017, sequence version 2.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=ribonuclease H {ECO:0000256|ARBA:ARBA00012180};
DE EC=3.1.26.4 {ECO:0000256|ARBA:ARBA00012180};
GN ORFNames=VFPPC_12642 {ECO:0000313|EMBL:OAQ57224.2};
OS Pochonia chlamydosporia 170.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Clavicipitaceae; Pochonia.
OX NCBI_TaxID=1380566 {ECO:0000313|EMBL:OAQ57224.2, ECO:0000313|Proteomes:UP000078397};
RN [1] {ECO:0000313|EMBL:OAQ57224.2, ECO:0000313|Proteomes:UP000078397}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=170 {ECO:0000313|EMBL:OAQ57224.2};
RX PubMed=27416025;
RA Wang G., Liu Z., Lin R., Li E., Mao Z., Ling J., Yang Y., Yin W.B., Xie B.;
RT "Biosynthesis of antibiotic leucinostatins in bio-control fungus
RT Purpureocillium lilacinum and their inhibition on phytophthora revealed by
RT genome mining.";
RL PLoS Pathog. 12:E1005685-E1005685(2016).
CC -!- SIMILARITY: Belongs to the RNase H family.
CC {ECO:0000256|ARBA:ARBA00005300}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OAQ57224.2}.
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DR EMBL; LSBJ02000033; OAQ57224.2; -; Genomic_DNA.
DR AlphaFoldDB; A0A179EVH5; -.
DR STRING; 1380566.A0A179EVH5; -.
DR OrthoDB; 1438008at2759; -.
DR Proteomes; UP000078397; Unassembled WGS sequence.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0004523; F:RNA-DNA hybrid ribonuclease activity; IEA:InterPro.
DR GO; GO:0090304; P:nucleic acid metabolic process; IEA:UniProt.
DR CDD; cd13934; RNase_H_Dikarya_like; 1.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR002156; RNaseH_domain.
DR InterPro; IPR036397; RNaseH_sf.
DR PANTHER; PTHR10642; RIBONUCLEASE H1; 1.
DR PANTHER; PTHR10642:SF26; RIBONUCLEASE H1; 1.
DR Pfam; PF00075; RNase_H; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR PROSITE; PS50879; RNASE_H_1; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000078397}.
FT DOMAIN 216..346
FT /note="RNase H type-1"
FT /evidence="ECO:0000259|PROSITE:PS50879"
FT REGION 1..21
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 39..71
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 54..69
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 346 AA; 37811 MW; C755420AC03BE031 CRC64;
MSPGSFEYSS ASPVNSPRTT AQYNSTMLSH LHVIDDSDAD DGIGHVVDDS ESDDGSGYVV
DDSDSDDSIG PVELPDGRLV CRPHGLTFCP YCCVDFSFME ELLEDPEERL ERETNELYEQ
LSDEMQADID ARWGSPRRLA DGPAYHGNNG TKTGFHIIDT AASSEPCGRT IRRGTGRVFP
TKFNPPSATS APGVLFPAGI GHQAIPPVAR FIRRDDSEQL LIYADGACLN NGQPNPKAGW
AFVFKPDTNQ PSGIVSARLE KKGPFGDAFA QTSNRAELRA VLAALRFRHW RGGGFSTLVF
ATDSEYVAEG ATSWIRGWVR NGWKTSTGAD VKNKDMWEVL LGEVER
//
