ID   A0A179EXS1_PURLI        Unreviewed;      1155 AA.
AC   A0A179EXS1;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   SubName: Full=Reverse transcriptase {ECO:0000313|EMBL:OAQ57981.1};
GN   ORFNames=VFPFJ_11702 {ECO:0000313|EMBL:OAQ57981.1};
OS   Purpureocillium lilacinum (Paecilomyces lilacinus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Hypocreales; Ophiocordycipitaceae; Purpureocillium.
OX   NCBI_TaxID=33203 {ECO:0000313|EMBL:OAQ57981.1, ECO:0000313|Proteomes:UP000078340};
RN   [1] {ECO:0000313|EMBL:OAQ57981.1, ECO:0000313|Proteomes:UP000078340}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PLFJ-1 {ECO:0000313|EMBL:OAQ57981.1};
RA   Wang G., Liu Z., Lin R., Li E., Mao Z., Ling J., Yin W., Xie B.;
RT   "Biosynthesis of antibiotic leucinostatins and their inhibition on
RT   Phytophthora in bio-control Purpureocillium lilacinum.";
RL   Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OAQ57981.1}.
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DR   EMBL; LSBI01000076; OAQ57981.1; -; Genomic_DNA.
DR   RefSeq; XP_018172651.1; XM_018328769.1.
DR   AlphaFoldDB; A0A179EXS1; -.
DR   STRING; 33203.A0A179EXS1; -.
DR   GeneID; 28893818; -.
DR   KEGG; plj:VFPFJ_11702; -.
DR   OMA; EREIWIA; -.
DR   OrthoDB; 2623044at2759; -.
DR   Proteomes; UP000078340; Unassembled WGS sequence.
DR   GO; GO:0005739; C:mitochondrion; IEA:UniProtKB-KW.
DR   GO; GO:0003964; F:RNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR   CDD; cd01650; RT_nLTR_like; 1.
DR   Gene3D; 3.60.10.10; Endonuclease/exonuclease/phosphatase; 1.
DR   InterPro; IPR043502; DNA/RNA_pol_sf.
DR   InterPro; IPR036691; Endo/exonu/phosph_ase_sf.
DR   InterPro; IPR005135; Endo/exonuclease/phosphatase.
DR   InterPro; IPR000477; RT_dom.
DR   PANTHER; PTHR33481; REVERSE TRANSCRIPTASE; 1.
DR   PANTHER; PTHR33481:SF1; REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF14529; Exo_endo_phos_2; 1.
DR   Pfam; PF00078; RVT_1; 1.
DR   PRINTS; PR01345; CERVTRCPTASE.
DR   SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR   SUPFAM; SSF56219; DNase I-like; 1.
DR   PROSITE; PS50878; RT_POL; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Mitochondrion {ECO:0000256|ARBA:ARBA00023128};
KW   Nucleotidyltransferase {ECO:0000313|EMBL:OAQ57981.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000078340};
KW   RNA-directed DNA polymerase {ECO:0000313|EMBL:OAQ57981.1};
KW   Transferase {ECO:0000313|EMBL:OAQ57981.1}.
FT   DOMAIN          784..1045
FT                   /note="Reverse transcriptase"
FT                   /evidence="ECO:0000259|PROSITE:PS50878"
FT   COILED          26..85
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   1155 AA;  128682 MW;  1820568F8693268F CRC64;
     MGGEIGELKQ RITEQNDTIC KQSNVIKGQE DLIRELQTQM KESSDELHRE NKEARVELQN
     TQKELQATKE ELKHIRTQLE ALSAAAASNQ SSARASCEPT NLRSLSMQST PSSFSDTLYC
     TIDTSRVEQA NESRAQAGQI RQAIESEMRA KQGQDAWRCA AVVKDARNTD RVKIICRDET
     ELQQVKEVAQ KTAVVGARVM RDQLYPVKID NANRTAVLDT EGNVLAGAAE ALGTENNVTI
     GKISWLSNKE SGKAYGSMVV YVTKGSDAKK LLDGHYFDLA GESAITNVFE PRAGPIQCFN
     CQEIGHKALQ LNVRKQEPVQ LSLMNDGDLR EFGVIAVSEP YARTVDGRVT TSPTGHRNWT
     KMIPTSTHDA PWPIRSMLWV RSDIEAEQMP IQSADLTAAV LRLPARDVLV VSVYVEWNND
     QALTAAMTLL DDLIRKFRDG TGRRTDVVLA GDFNRHDFLW GGDEVSARRQ GEGEPIIDLM
     SEHGLCSLLP RGTKTWQGPE SESTIDLVLA KSELADEMVA CAIHPTEHGS DHRAIQTTFD
     VEMPERSAPE RLLFKNAPWI MIAAKVEDDL RPLPWTVDVQ IQADQMMRVV LEAIHELTPR
     APPLPYAKRN LTRLRRAYTF WRNQARTQRR AGSARPDLEQ RAKEAAKEYH DAIRKQKTSH
     WDEFVAEDVN IWKAAKYLKP SKDVADDKVP PLRRADGSTT GDKADQVEEL LATFFPPLPA
     RIEAEGERPQ RAPVPMPDLT LEEIEEKVMA AKPWKAPGED GLPAIVWKKL WHVVKYRVWT
     LFDSSIRDGV VPHQWRTAKI IPLKKPERGD YTVAKAWRPI SLLSTLGKVL EVVVAERLSY
     AVEAYGLLPA NHFGARKRRS ADQALMLLQE QIYKAWRMGR VLSLISFDVK GAYNGVCKER
     LLERLRARGI PEGLVRWIGA FCSERSASIV VNGQASDRQA LPQAGLPQGS PLSPILFLFF
     NADLVQRKIS TAGGSVAFVD DYSAWVTGPT AEANRAGLES IINDALEWEK RSGATFEADK
     TTIIHFTRMA ERNSETAYTI KGQEVKPTSS AKILGVIMDS ELRYKEHMAR AAAKGLSAAM
     DLRRLRMASP RMARQLFVAT VAPTVDYASN VWSHTCGLRE AAWLDKAQRV GAQAITGTFR
     TVATAVAEAE ASIQP
//