ID A0A179F4G6_PURLI Unreviewed; 688 AA.
AC A0A179F4G6;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=chitinase {ECO:0000256|ARBA:ARBA00012729};
DE EC=3.2.1.14 {ECO:0000256|ARBA:ARBA00012729};
GN ORFNames=VFPFJ_11553 {ECO:0000313|EMBL:OAQ60073.1};
OS Purpureocillium lilacinum (Paecilomyces lilacinus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Ophiocordycipitaceae; Purpureocillium.
OX NCBI_TaxID=33203 {ECO:0000313|EMBL:OAQ60073.1, ECO:0000313|Proteomes:UP000078340};
RN [1] {ECO:0000313|EMBL:OAQ60073.1, ECO:0000313|Proteomes:UP000078340}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PLFJ-1 {ECO:0000313|EMBL:OAQ60073.1};
RA Wang G., Liu Z., Lin R., Li E., Mao Z., Ling J., Yin W., Xie B.;
RT "Biosynthesis of antibiotic leucinostatins and their inhibition on
RT Phytophthora in bio-control Purpureocillium lilacinum.";
RL Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Random endo-hydrolysis of N-acetyl-beta-D-glucosaminide
CC (1->4)-beta-linkages in chitin and chitodextrins.; EC=3.2.1.14;
CC Evidence={ECO:0000256|ARBA:ARBA00000822};
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OAQ60073.1}.
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DR EMBL; LSBI01000045; OAQ60073.1; -; Genomic_DNA.
DR RefSeq; XP_018172807.1; XM_018328620.1.
DR AlphaFoldDB; A0A179F4G6; -.
DR STRING; 33203.A0A179F4G6; -.
DR GeneID; 28893669; -.
DR KEGG; plj:VFPFJ_11553; -.
DR OMA; KCHESTN; -.
DR OrthoDB; 360175at2759; -.
DR Proteomes; UP000078340; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0098552; C:side of membrane; IEA:UniProtKB-KW.
DR GO; GO:0008061; F:chitin binding; IEA:UniProtKB-KW.
DR GO; GO:0004568; F:chitinase activity; IEA:UniProtKB-EC.
DR GO; GO:0006032; P:chitin catabolic process; IEA:UniProtKB-KW.
DR GO; GO:0000272; P:polysaccharide catabolic process; IEA:UniProtKB-KW.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR InterPro; IPR001223; Glyco_hydro18_cat.
DR InterPro; IPR001579; Glyco_hydro_18_chit_AS.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR45708; ENDOCHITINASE; 1.
DR PANTHER; PTHR45708:SF49; ENDOCHITINASE; 1.
DR Pfam; PF00704; Glyco_hydro_18; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR PROSITE; PS01095; GH18_1; 1.
DR PROSITE; PS51910; GH18_2; 1.
PE 4: Predicted;
KW Carbohydrate metabolism {ECO:0000256|ARBA:ARBA00023277};
KW Chitin degradation {ECO:0000256|ARBA:ARBA00023024};
KW Chitin-binding {ECO:0000256|ARBA:ARBA00022669};
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295, ECO:0000256|RuleBase:RU000489};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU000489};
KW Polysaccharide degradation {ECO:0000256|ARBA:ARBA00023326};
KW Reference proteome {ECO:0000313|Proteomes:UP000078340}.
FT DOMAIN 17..332
FT /note="GH18"
FT /evidence="ECO:0000259|PROSITE:PS51910"
FT REGION 332..449
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 641..661
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 688 AA; 71662 MW; D4BFF4A542947262 CRC64;
MSLSVRGVVG ASVGAFGALN GYWGQKDNQG LRAYCDSGVS SVTLGFINSA PEHDKSDLKY
PGINFSTHCW AETYTDKNGV PSPLYEYCQS LKTDIPYCQD KGVKVILSIG GMYSSANNYK
VSTTANGVHF ADKLYQIFGP YNPTAGVARP FDSPDRHVAV DGFDFDLEVE LDNKPYIAMI
NRLRALDNSL IITGAPQCPL STTPNVMAEL LQQASFDALF IQFYNNPVCD YVGDGNGDKF
NLDEWVSFMA KSNSKSAKLY VGLPGGPTSN SARSGYISPD KVKELVCKYS TKTPNWGGIS
VWDLDTAAAN VVNGKNFKQH VADALKYGCR PVPTTTSTTA SSTKSSSSST IRASSTTTSS
TTKVSSTTSS STSSSTSKAS STASSTSVAS STTVSSATDS SSSSTKVLSS SSTKAISSTA
KPTSATTTDV TSPPVPTSTP VTSIVSSTTK WSNSTITSGT VSMTTSTVYT TSVHTVTKCP
PYVANCPNGG YVTTETVPLY TTVCPVTKTP KPPQPTQAKT SAAWTTSTVY TTKIHTVTAC
PPQIANCPVG HVTTETIPWY TTVCPVTETE TGKVPQPTPS VPGDVYPPLL ESTSATLAKS
SITETVTNPA DVALKPSCSG PGCPGVSSGV VVPTLSWTTT PDAPSQGFTS TPGGPSAVPS
NPVQAGASTL ALSLSGLVVM AAFQVFAL
//
