ID A0A179FER2_PURLI Unreviewed; 730 AA.
AC A0A179FER2;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Sensor histidine kinase/response regulator Fos-1 {ECO:0000313|EMBL:OAQ63790.1};
GN ORFNames=VFPFJ_11389 {ECO:0000313|EMBL:OAQ63790.1};
OS Purpureocillium lilacinum (Paecilomyces lilacinus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Ophiocordycipitaceae; Purpureocillium.
OX NCBI_TaxID=33203 {ECO:0000313|EMBL:OAQ63790.1, ECO:0000313|Proteomes:UP000078340};
RN [1] {ECO:0000313|EMBL:OAQ63790.1, ECO:0000313|Proteomes:UP000078340}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PLFJ-1 {ECO:0000313|EMBL:OAQ63790.1};
RA Wang G., Liu Z., Lin R., Li E., Mao Z., Ling J., Yin W., Xie B.;
RT "Biosynthesis of antibiotic leucinostatins and their inhibition on
RT Phytophthora in bio-control Purpureocillium lilacinum.";
RL Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OAQ63790.1}.
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DR EMBL; LSBI01000030; OAQ63790.1; -; Genomic_DNA.
DR RefSeq; XP_018172985.1; XM_018328456.1.
DR AlphaFoldDB; A0A179FER2; -.
DR GeneID; 28893505; -.
DR KEGG; plj:VFPFJ_11389; -.
DR OMA; VGFHANP; -.
DR OrthoDB; 1222064at2759; -.
DR Proteomes; UP000078340; Unassembled WGS sequence.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd16922; HATPase_EvgS-ArcB-TorS-like; 1.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd00130; PAS; 1.
DR CDD; cd17546; REC_hyHK_CKI1_RcsC-like; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR43047:SF79; HISTIDINE KINASE; 1.
DR PANTHER; PTHR43047; TWO-COMPONENT HISTIDINE PROTEIN KINASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF13426; PAS_9; 1.
DR Pfam; PF00072; Response_reg; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00448; REC; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF52172; CheY-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50113; PAC; 1.
DR PROSITE; PS50112; PAS; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:OAQ63790.1};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553, ECO:0000256|PROSITE-
KW ProRule:PRU00169}; Reference proteome {ECO:0000313|Proteomes:UP000078340};
KW Transferase {ECO:0000313|EMBL:OAQ63790.1}.
FT DOMAIN 179..252
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 254..305
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 320..541
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT DOMAIN 587..704
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT REGION 1..43
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 15..36
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 639
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 730 AA; 80625 MW; 781C192286E29FA9 CRC64;
MIRGRKRPAE DDPLTDRSTL SSTVASFPTP QQPLRISKAP TGGPAAVSEM SGLLDYSPVP
TLLVSPSNRI QRASIALLEA WDCRRDQLVD RDLFISLYEG SLTERFDRIP LVYAIESAIT
ARAVRLCHAA YVAGSVSWNA RILPIHRDEE LLGLMLEWEV DKVNVTVADG EVPRNRLPNE
DAFRILVQAV KELAIFLLDT RGNLVTWKTG AELDEGYEKE EIVGKHFSIF YSADDVQSHK
PERALEISLR EGRAEDEGWR YRKDGTRFWA NVVIIPIYNH GVHVGFGKVT RDLTERKEAE
LRLIAAYEES GKLKSDFLAN ISHEIRTPMH GMLSACALLL DSGLTEKQLE MANMIEDSGR
VMLQIINDTL DYSKLAAYSL SINSDIMDVA SIIASVVGSC RASLNPGVSL KLHLAPDLPK
WADGDALRFR QVAENIVSNA AKFTERGLIQ MSVSLLTQDA GTYTIMTEVA DAGPGLSNKE
VPKLFEPFTQ LDTTYQKRRE GTGLGLSIAK SLAGLMGGDI GYRPNPESQG SIFWFTVKLK
RINNILEVRS VGDQDFGKTT KQLHVTQDDD NSAGELAQLM EIAPAARILA AEDNIINQKV
LVGTLRAVGF QHITVVSDGA QAVSVLSKTP NAFDLVLMDI SMPIMNGYEA TIQIRNSGIR
LPILAMTAYA LKGDMERCLE NGADDYIVKP IHRQLLVRKL LQWLIKPCDS RHQEVGHHQS
AIGDSDVASV
//
