ID A0A179FF48_METCM Unreviewed; 1498 AA.
AC A0A179FF48;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=ABC transporter CDR4 {ECO:0000313|EMBL:OAQ63679.1};
GN ORFNames=VFPPC_16504 {ECO:0000313|EMBL:OAQ63679.1};
OS Pochonia chlamydosporia 170.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Clavicipitaceae; Pochonia.
OX NCBI_TaxID=1380566 {ECO:0000313|EMBL:OAQ63679.1, ECO:0000313|Proteomes:UP000078397};
RN [1] {ECO:0000313|EMBL:OAQ63679.1, ECO:0000313|Proteomes:UP000078397}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=170 {ECO:0000313|EMBL:OAQ63679.1};
RX PubMed=27416025;
RA Wang G., Liu Z., Lin R., Li E., Mao Z., Ling J., Yang Y., Yin W.B., Xie B.;
RT "Biosynthesis of antibiotic leucinostatins in bio-control fungus
RT Purpureocillium lilacinum and their inhibition on phytophthora revealed by
RT genome mining.";
RL PLoS Pathog. 12:E1005685-E1005685(2016).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. ABCG family.
CC PDR (TC 3.A.1.205) subfamily. {ECO:0000256|ARBA:ARBA00006012}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OAQ63679.1}.
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DR EMBL; LSBJ02000006; OAQ63679.1; -; Genomic_DNA.
DR RefSeq; XP_018141259.1; XM_018294257.1.
DR STRING; 1380566.A0A179FF48; -.
DR GeneID; 28858251; -.
DR KEGG; pchm:VFPPC_16504; -.
DR OrthoDB; 5473955at2759; -.
DR Proteomes; UP000078397; Chromosome 6.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd03232; ABCG_PDR_domain2; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR013525; ABC2_TM.
DR InterPro; IPR029481; ABC_trans_N.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR034003; ABCG_PDR_2.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR010929; PDR_CDR_ABC.
DR PANTHER; PTHR19241; ATP-BINDING CASSETTE TRANSPORTER; 1.
DR PANTHER; PTHR19241:SF625; ATP-DEPENDENT PERMEASE PDR10-RELATED; 1.
DR Pfam; PF01061; ABC2_membrane; 2.
DR Pfam; PF00005; ABC_tran; 2.
DR Pfam; PF14510; ABC_trans_N; 1.
DR Pfam; PF06422; PDR_CDR; 1.
DR SMART; SM00382; AAA; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000078397};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 506..529
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 541..563
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 584..609
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 615..639
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 651..672
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 755..775
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1192..1213
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1225..1247
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1268..1291
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1311..1334
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1341..1360
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1467..1485
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 147..397
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT DOMAIN 853..1096
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT REGION 27..88
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 811..843
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 43..86
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1498 AA; 167988 MW; C4767130C5437C3F CRC64;
MYKFSNKHIE HIFDGKVADM TLMSSSQGSH STLVDRDKDV NQRASSGQSP PQQTPVQRSI
APSLSNYTTE SNTAPHKGSN LDPKSPNFDP TAWMKRVAAL TESGRRSASQ RSLGVAFRNL
TVFGWITEAQ FQKSTGNVLI GIAKSLARLA SGSGFRGRRV DILQNFEGIV EDGEMLLVLG
PPGSGCSTFL KTLSSQTADL ELSPDAYINY RGIDPKLIRS SLRGDVLYNA ELDSHLAHLT
VNETLLFASC ARSVRHVPQG FTRQQFDVLR RDAMMATFGL THTANTRVGD DVVRGVSGGE
RKRVSIAEAA LTNAKFQCWD NSTRGLDSAN AVNFCQNLRR QADLLGTTSA VTLYQVPQSA
YDLFDLVTVI YEGRQIFFGK CSEAKTYFED LGFLCPERQT VPDFLTSMTS PLERTVKAGF
ENLAPRTADD FALWWRSSKL RRELQHRLNS YENKHPVQHR LSEYLESRHA EQAKSQSHSS
PYTISYYRQV SLTFWRAWRR LLADPGFTIV SLVFNLIVAL ILGSMFYNLP NNSSSFYYRG
GTIFFSLLFN AFASQLEVLT LYAERPVVEK HNRYAFHRQS AQAIASYLCD IPYKIVNMFV
FNILVYFMAH LRRGPGAFFF FCLVSLLATL SLSAIFRTLA SIARTSAQAM IPSAVISFGL
MIYTGFTIPT AYMPGWSRWM TYINPLAYSF EALMANEFHG REFACSSIVP RGRGYERLPA
RSRICAVVGA KPGSTVVNGD RYINLSFDYW NDHKWRNVGI LCAFTVVFFA AYLLAAELAR
PPKTKGEVLV FRRSHRTSRS SLMDSFLPRS DLETAQSSRG SQSSRLEKSN IVNHEASSDG
NVTKPLAATT QAFHWEDLCY SIKVKGEERQ LLDHVDGWVK PGVSTVLMGV SGAGKTTLLD
TLACRVSLGV VSGDVLVNGT PTDATFQHQV GYVQQQDLHM ATMSVREALT FSAVLRQPAE
VPRSDKLRYV DHVIEVLEMQ DFAEAIIGIP GQGLNIEQRK RFTIGVELAA RPQLLIFFDE
PTSGLDAQTS WAISVLIRKL ANSGQAVLCT VHQPSAMLFN QFDRLLLIAP GGKTVYFGDL
GEHSSTLIDY FERSGATPIL PGANPAEWML KVIEPQKNLS EGVDWHATWR NSPEYQGVKT
ELARLRGLRL TETNAAGRSS EKSQHQEFVA SFATQFREVL IRTAKHFWRS PVYMWSKIGL
ITLSSLYLGF SYSANNSIQG LQNQLWAVFM FLVLFLNISE QIMPMFVPQR NLYEARERPS
KIYRWATYVL ANILIEIFWN SLMAVIMYFC WYYPVGFFRN TTSDDQTVRG FLVFLFLWVY
LLFTSTITHA AIMWMDLPET AGVLITFLWT LCILCCGISV PQVDLPRFWT FMYRASPATY
LVGGIMSTAV AHNNITCADY EVLRIAPPAD GMSCGKFLGP FASKMGGRVL DEAALGICGY
CPVATTNDFL ARFGISYDTR WRDFGLVWVY VVANIGIALT LYWVFRVPSQ KKTQAKRV
//
