ID   A0A179FL70_METCM        Unreviewed;       555 AA.
AC   A0A179FL70;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   27-MAR-2024, entry version 37.
DE   SubName: Full=26S protease regulatory subunit 4 {ECO:0000313|EMBL:OAQ66332.1};
GN   ORFNames=VFPPC_07900 {ECO:0000313|EMBL:OAQ66332.1};
OS   Pochonia chlamydosporia 170.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Hypocreales; Clavicipitaceae; Pochonia.
OX   NCBI_TaxID=1380566 {ECO:0000313|EMBL:OAQ66332.1, ECO:0000313|Proteomes:UP000078397};
RN   [1] {ECO:0000313|EMBL:OAQ66332.1, ECO:0000313|Proteomes:UP000078397}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=170 {ECO:0000313|EMBL:OAQ66332.1};
RX   PubMed=27416025;
RA   Wang G., Liu Z., Lin R., Li E., Mao Z., Ling J., Yang Y., Yin W.B., Xie B.;
RT   "Biosynthesis of antibiotic leucinostatins in bio-control fungus
RT   Purpureocillium lilacinum and their inhibition on phytophthora revealed by
RT   genome mining.";
RL   PLoS Pathog. 12:E1005685-E1005685(2016).
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC   -!- SIMILARITY: Belongs to the AAA ATPase family.
CC       {ECO:0000256|ARBA:ARBA00006914, ECO:0000256|RuleBase:RU003651}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OAQ66332.1}.
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DR   EMBL; LSBJ02000004; OAQ66332.1; -; Genomic_DNA.
DR   RefSeq; XP_018143419.1; XM_018286691.1.
DR   AlphaFoldDB; A0A179FL70; -.
DR   STRING; 1380566.A0A179FL70; -.
DR   GeneID; 28850685; -.
DR   KEGG; pchm:VFPPC_07900; -.
DR   OrthoDB; 1707207at2759; -.
DR   Proteomes; UP000078397; Chromosome 4.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0008540; C:proteasome regulatory particle, base subcomplex; IEA:UniProt.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   GO; GO:0008233; F:peptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   CDD; cd19502; RecA-like_PAN_like; 1.
DR   Gene3D; 1.10.8.60; -; 1.
DR   Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR041569; AAA_lid_3.
DR   InterPro; IPR003959; ATPase_AAA_core.
DR   InterPro; IPR003960; ATPase_AAA_CS.
DR   InterPro; IPR012340; NA-bd_OB-fold.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR032501; Prot_ATP_ID_OB_2nd.
DR   PANTHER; PTHR23073; 26S PROTEASOME REGULATORY SUBUNIT; 1.
DR   PANTHER; PTHR23073:SF24; 26S PROTEASOME REGULATORY SUBUNIT 4; 1.
DR   Pfam; PF00004; AAA; 1.
DR   Pfam; PF17862; AAA_lid_3; 1.
DR   Pfam; PF16450; Prot_ATP_ID_OB_C; 1.
DR   SMART; SM00382; AAA; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS00674; AAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|RuleBase:RU003651};
KW   Hydrolase {ECO:0000313|EMBL:OAQ66332.1};
KW   Nucleotide-binding {ECO:0000256|RuleBase:RU003651};
KW   Protease {ECO:0000313|EMBL:OAQ66332.1};
KW   Proteasome {ECO:0000256|ARBA:ARBA00022942};
KW   Reference proteome {ECO:0000313|Proteomes:UP000078397}.
FT   DOMAIN          333..472
FT                   /note="AAA+ ATPase"
FT                   /evidence="ECO:0000259|SMART:SM00382"
FT   REGION          120..147
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   555 AA;  61476 MW;  D1D06F3B92CC12AB CRC64;
     MTVAAHMVAL ARDLSFQPPR DPALSCRVSL APDGDCPNPL SVIALNLVIN SSINGNHLQP
     TVLHSDLAER VIGLPEYSFT GSQSLIRQDG KLISWRLVIY SLLTVDENRV KDNLAWEAKD
     KPKYEPPPRP TTRVGRKKRK AGGTSAAAKL PAVYPTSRCK LRLLRMQRIH DHLLLEEEYV
     ENQERLRKAK AAKEGAAVGP DADVDRLADE RGRVDDMRGS PMGVGTLEEL IDDDHAIVSS
     TTGPEYYVSI MSFVDKDLLE PGASVLLHHK SVSIVGVLTD DTDPIVSVMK LDKAPTESYA
     DIGGLESQIQ EVRESVELPL LHPELYEEMG IKPPKGVILY GAPGTGKTLL AKAVANQTSA
     TFLRIVGSEL IQKYLGDGPR LVRQLFQVAG ENAPSIVFID EIDAIGTKRY ESTSGGEREV
     QRTMLELLNQ LDGFDDRGDV KVIMATNKID TLDPALIRPG RIDRKILFEN PDQNTKRKIF
     TLHTSKMNLN DDVDLEEFIS QKDDLSGADI KAICSEAGMM ALRERRMRVQ MADFRSARER
     VLRTKQEGEP EGLYL
//