ID A0A179FTH9_METCM Unreviewed; 373 AA.
AC A0A179FTH9;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=2OG-Fe oxygenase superfamily protein {ECO:0000313|EMBL:OAQ68912.1};
GN ORFNames=VFPPC_15896 {ECO:0000313|EMBL:OAQ68912.1};
OS Pochonia chlamydosporia 170.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Clavicipitaceae; Pochonia.
OX NCBI_TaxID=1380566 {ECO:0000313|EMBL:OAQ68912.1, ECO:0000313|Proteomes:UP000078397};
RN [1] {ECO:0000313|EMBL:OAQ68912.1, ECO:0000313|Proteomes:UP000078397}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=170 {ECO:0000313|EMBL:OAQ68912.1};
RX PubMed=27416025;
RA Wang G., Liu Z., Lin R., Li E., Mao Z., Ling J., Yang Y., Yin W.B., Xie B.;
RT "Biosynthesis of antibiotic leucinostatins in bio-control fungus
RT Purpureocillium lilacinum and their inhibition on phytophthora revealed by
RT genome mining.";
RL PLoS Pathog. 12:E1005685-E1005685(2016).
CC -!- SIMILARITY: Belongs to the iron/ascorbate-dependent oxidoreductase
CC family. {ECO:0000256|ARBA:ARBA00008056, ECO:0000256|RuleBase:RU003682}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OAQ68912.1}.
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DR EMBL; LSBJ02000003; OAQ68912.1; -; Genomic_DNA.
DR RefSeq; XP_018145762.1; XM_018293649.1.
DR AlphaFoldDB; A0A179FTH9; -.
DR STRING; 1380566.A0A179FTH9; -.
DR GeneID; 28857643; -.
DR KEGG; pchm:VFPPC_15896; -.
DR OrthoDB; 2908779at2759; -.
DR Proteomes; UP000078397; Chromosome 3.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR GO; GO:1901362; P:organic cyclic compound biosynthetic process; IEA:UniProt.
DR GO; GO:0044283; P:small molecule biosynthetic process; IEA:UniProt.
DR InterPro; IPR026992; DIOX_N.
DR InterPro; IPR044861; IPNS-like_FE2OG_OXY.
DR InterPro; IPR027443; IPNS-like_sf.
DR InterPro; IPR005123; Oxoglu/Fe-dep_dioxygenase.
DR PANTHER; PTHR47990; 2-OXOGLUTARATE (2OG) AND FE(II)-DEPENDENT OXYGENASE SUPERFAMILY PROTEIN-RELATED; 1.
DR PANTHER; PTHR47990:SF62; IRON_ASCORBATE OXIDOREDUCTASE DDB_G0283291-RELATED; 1.
DR Pfam; PF03171; 2OG-FeII_Oxy; 1.
DR Pfam; PF14226; DIOX_N; 1.
DR PRINTS; PR00682; IPNSYNTHASE.
DR SUPFAM; SSF51197; Clavaminate synthase-like; 1.
DR PROSITE; PS51471; FE2OG_OXY; 1.
PE 3: Inferred from homology;
KW Iron {ECO:0000256|RuleBase:RU003682};
KW Metal-binding {ECO:0000256|RuleBase:RU003682};
KW Oxidoreductase {ECO:0000256|RuleBase:RU003682};
KW Reference proteome {ECO:0000313|Proteomes:UP000078397}.
FT DOMAIN 216..326
FT /note="Fe2OG dioxygenase"
FT /evidence="ECO:0000259|PROSITE:PS51471"
SQ SEQUENCE 373 AA; 42246 MW; 9EA3E04D5440A97F CRC64;
MATATQTGTT QIRVASPTGP VTRTILRTPL RDALPSEIPI IDVSPIFSSS LEDRKSVAQQ
VRNAATNTGF FYIKNHGVPN HVTQESYNAA LEFFRQDVDK KNEASITKSA RYNGYRAPDT
QRVNPDEGID VRESFSITYD PRIDTEVNKV QEIPENVMEY IRMEEGHWEN TSNLPNFKCS
VINHYQSCLS LARALTRTFA LSLDLPETAF DSKVVYPDAG INMNYYPPIP NNQSLTPTDP
NARVSIGSHT DFPVFTILWQ DNVGGLQVLS RDGQWINAKP IPDTFVVNIA DCLQRITNDK
YVSTIHRAQN WSGKERVSIG FFWGFGFHET CAVLDNCLAP GEKKKYEDIN CWEWLKKRVY
DMTQLDEECK KSS
//
