ID A0A179FTS5_METCM Unreviewed; 971 AA.
AC A0A179FTS5;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=mRNA transport regulator {ECO:0000313|EMBL:OAQ68994.1};
GN ORFNames=VFPPC_05139 {ECO:0000313|EMBL:OAQ68994.1};
OS Pochonia chlamydosporia 170.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Clavicipitaceae; Pochonia.
OX NCBI_TaxID=1380566 {ECO:0000313|EMBL:OAQ68994.1, ECO:0000313|Proteomes:UP000078397};
RN [1] {ECO:0000313|EMBL:OAQ68994.1, ECO:0000313|Proteomes:UP000078397}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=170 {ECO:0000313|EMBL:OAQ68994.1};
RX PubMed=27416025;
RA Wang G., Liu Z., Lin R., Li E., Mao Z., Ling J., Yang Y., Yin W.B., Xie B.;
RT "Biosynthesis of antibiotic leucinostatins in bio-control fungus
RT Purpureocillium lilacinum and their inhibition on phytophthora revealed by
RT genome mining.";
RL PLoS Pathog. 12:E1005685-E1005685(2016).
CC -!- FUNCTION: tRNA nucleus export receptor which facilitates tRNA
CC translocation across the nuclear pore complex. Involved in pre-tRNA
CC splicing, probably by affecting the interaction of pre-tRNA with
CC splicing endonuclease. {ECO:0000256|ARBA:ARBA00025147}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OAQ68994.1}.
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DR EMBL; LSBJ02000003; OAQ68994.1; -; Genomic_DNA.
DR RefSeq; XP_018145844.1; XM_018284379.1.
DR AlphaFoldDB; A0A179FTS5; -.
DR STRING; 1380566.A0A179FTS5; -.
DR GeneID; 28848373; -.
DR KEGG; pchm:VFPPC_05139; -.
DR OrthoDB; 35663at2759; -.
DR Proteomes; UP000078397; Chromosome 3.
DR GO; GO:0005634; C:nucleus; IEA:UniProt.
DR GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR GO; GO:0006606; P:protein import into nucleus; IEA:UniProt.
DR GO; GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR013598; Exportin-1/Importin-b-like.
DR InterPro; IPR001494; Importin-beta_N.
DR PANTHER; PTHR12363:SF53; MRNA TRANSPORT REGULATOR MTR10; 1.
DR PANTHER; PTHR12363; TRANSPORTIN 3 AND IMPORTIN 13; 1.
DR Pfam; PF03810; IBN_N; 1.
DR Pfam; PF08389; Xpo1; 1.
DR SMART; SM00913; IBN_N; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR PROSITE; PS50166; IMPORTIN_B_NT; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000078397};
KW tRNA processing {ECO:0000256|ARBA:ARBA00022694}.
FT DOMAIN 33..100
FT /note="Importin N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS50166"
SQ SEQUENCE 971 AA; 109224 MW; 82B1EE61F44FEC38 CRC64;
MASNGSQETF SPSDVLAAVR TMRTGEKETK TKAHEYLERF QKSKDSWGTI MGILQSTAEP
EATLFAAITL RGKITYDLTT QVLPSELPAL RSQILLLLKH FAPGPKPIRV QLCVCLAILA
IQMKDWIDVL PSVVQSLGDS PESHACILDF LRVLPEEVTE GRKITLSEEE LAARTQVLLG
DNTDQVVQLL ISYSQSSDAA SRNPQLMECI TSWLREVPIM SIINSPLLEH IFTGVSSDEC
GAEAAECLCT MLRETRDIDE SQDAVHALYP RVVALKSQIA KAAEEEDTDK LKALTKVFST
AAISWVVAIA REPSHFRPLV EAVLECAARD TDRDVIEHTF DFWYELKQYL VLERYIQGRL
ELVDIYSKLV DILLKHLEYP RPESGNESDL FDGDREQEEK FREFRHRMGD TLKDSCDVMG
VTECLTKVLQ AIQLWTQKYA GQVNGPNVPH WQELEAPLFA MRALGRMVHK DESIVLPQLM
PLLVQIPSHE KLRFATIMVL GRYTEWTAAH PEYLEPQFNY IVESFQTDSK EILRAAALSL
KFFCTDCRDL LSGQVLQLQT FYDQILDKLP DLSKEEITEG VANVVAVQPV AETYRLLKTC
CDPLVQRLMA KANNATNEEG KLALADHLQL ITIFVQNVIP YVTPGEENPA VKYWQEVFPI
LSTVLDNFLD FSPICERICR CWRNMVTSYR TAMAPLLPEM ANKLASSFNT SREGCFLWVT
SAILREFSED REHLDQATTE NIYTFFEAQT TAFLRVMADL QPKDLPDVID DFFRLLIDAL
LYYPQKLIPS SLLAPIFQAS VYALTLEQRD PLSSTLHFLR DLLSYGGDNP ASSEGLPEAQ
AAEIRGIIKN LLMGHGADLV KQTMAGMMIT FPGDCFADGS GVILALFEIM PAQTTEWVAH
TIELLPQGSI SAPEAQRFVT KVKEKLSSGD VSGLRHVRTL LQDFTTNYRR RNVAPRDGLG
QLEAARFQFS G
//
