ID   A0A179FU57_METCM        Unreviewed;       741 AA.
AC   A0A179FU57;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   SubName: Full=Plasma membrane channel protein {ECO:0000313|EMBL:OAQ69175.1};
GN   ORFNames=VFPPC_05282 {ECO:0000313|EMBL:OAQ69175.1};
OS   Pochonia chlamydosporia 170.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Hypocreales; Clavicipitaceae; Pochonia.
OX   NCBI_TaxID=1380566 {ECO:0000313|EMBL:OAQ69175.1, ECO:0000313|Proteomes:UP000078397};
RN   [1] {ECO:0000313|EMBL:OAQ69175.1, ECO:0000313|Proteomes:UP000078397}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=170 {ECO:0000313|EMBL:OAQ69175.1};
RX   PubMed=27416025;
RA   Wang G., Liu Z., Lin R., Li E., Mao Z., Ling J., Yang Y., Yin W.B., Xie B.;
RT   "Biosynthesis of antibiotic leucinostatins in bio-control fungus
RT   Purpureocillium lilacinum and their inhibition on phytophthora revealed by
RT   genome mining.";
RL   PLoS Pathog. 12:E1005685-E1005685(2016).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OAQ69175.1}.
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DR   EMBL; LSBJ02000003; OAQ69175.1; -; Genomic_DNA.
DR   RefSeq; XP_018146025.1; XM_018284505.1.
DR   AlphaFoldDB; A0A179FU57; -.
DR   STRING; 1380566.A0A179FU57; -.
DR   GeneID; 28848499; -.
DR   KEGG; pchm:VFPPC_05282; -.
DR   OrthoDB; 49329at2759; -.
DR   Proteomes; UP000078397; Chromosome 3.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR007632; Anoctamin.
DR   InterPro; IPR049456; Anoctamin_N_fung.
DR   InterPro; IPR049452; Anoctamin_TM.
DR   PANTHER; PTHR12308; ANOCTAMIN; 1.
DR   PANTHER; PTHR12308:SF77; MEMBRANE STRESS RESPONSE PROTEIN (IST2), PUTATIVE (AFU_ORTHOLOGUE AFUA_4G03330)-RELATED; 1.
DR   Pfam; PF04547; Anoctamin; 1.
DR   Pfam; PF20877; Anoctamin_N; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000078397};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        214..239
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        245..264
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        317..340
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        360..382
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        402..424
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          50..174
FT                   /note="Anoctamin alpha-beta plait"
FT                   /evidence="ECO:0000259|Pfam:PF20877"
FT   DOMAIN          206..665
FT                   /note="Anoctamin transmembrane"
FT                   /evidence="ECO:0000259|Pfam:PF04547"
FT   REGION          1..46
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   741 AA;  84757 MW;  C9C50572E6FEA9CA CRC64;
     MFGPQVDLPP AQNRIHLTPP SPSDAGVPST TFHGYEKESR PSTPTQRETF NDKYVVLYDF
     GGIDYDVAGK ELNSLLDNLE AAGLHTEVRP GYEQTILVFV KAPSQLLGNT VYKQRVKDWL
     YAITQCHPGG DKDTIVKAWF EAEDVLALYH LILWPKEMGG AGITPEVGEW ENVKCIFPLH
     NEPMNQSILR HLSKRIILTV HDFDKIRDLH GSKVAFYFAF IQTYLMFLTF PAITGLLTWQ
     FLPKYSLAYA ILTGVWCTVF LEYWKIREVD LSIRWMVRGV NKVKINRPAF KYDRIVVDDN
     GRTRHYFPKW KQISRQLLQI PFIAMATIAL GLMICSVFVI EVLICETYEG PHQLYLEYLP
     TILLAVAIPR ISSSLEGIAT SLTEYENHRT ADEHEMSLTQ KVFILSIITN YLPILLTAFI
     YVPFGDVLIP QVKQSLVQLF PQFGSKLAFR PFASDTDRLR NEVIALTVTG QLSDFFEENI
     LPLIKYKFSD WYREYRRAYS KDTMLLTLVS DDPGESEFLK RVRNQATRSQ YNVQEDVAEL
     VLQFGYLALF SPVWPLISMG FLINNWIELR SDFAKICIEH QRPAPTRSDG IGPWVTALET
     LTLLGSISTA AIVHLFGSDT IGGGGWATLP ISIFVSEHLL LLLRALTRWI FERYGSEQIR
     KERSERYARR LHYLEEIEAN KRAGVNLSHA ERERRKSVLV ASCDSFWTKQ MEEGTSAAAG
     LRLINLARQW KKSQGNGEKL D
//