ID   A0A179G7K6_METCM        Unreviewed;       554 AA.
AC   A0A179G7K6;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   SubName: Full=Uracil permease {ECO:0000313|EMBL:OAQ73159.1};
GN   ORFNames=VFPPC_00949 {ECO:0000313|EMBL:OAQ73159.1};
OS   Pochonia chlamydosporia 170.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Hypocreales; Clavicipitaceae; Pochonia.
OX   NCBI_TaxID=1380566 {ECO:0000313|EMBL:OAQ73159.1, ECO:0000313|Proteomes:UP000078397};
RN   [1] {ECO:0000313|EMBL:OAQ73159.1, ECO:0000313|Proteomes:UP000078397}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=170 {ECO:0000313|EMBL:OAQ73159.1};
RX   PubMed=27416025;
RA   Wang G., Liu Z., Lin R., Li E., Mao Z., Ling J., Yang Y., Yin W.B., Xie B.;
RT   "Biosynthesis of antibiotic leucinostatins in bio-control fungus
RT   Purpureocillium lilacinum and their inhibition on phytophthora revealed by
RT   genome mining.";
RL   PLoS Pathog. 12:E1005685-E1005685(2016).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the purine-cytosine permease (2.A.39) family.
CC       {ECO:0000256|ARBA:ARBA00008974}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OAQ73159.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; LSBJ02000001; OAQ73159.1; -; Genomic_DNA.
DR   RefSeq; XP_018149242.1; XM_018280866.1.
DR   AlphaFoldDB; A0A179G7K6; -.
DR   GeneID; 28844860; -.
DR   KEGG; pchm:VFPPC_00949; -.
DR   OrthoDB; 1218881at2759; -.
DR   Proteomes; UP000078397; Chromosome 1.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   Gene3D; 1.10.4160.10; Hydantoin permease; 1.
DR   InterPro; IPR001248; Pur-cyt_permease.
DR   InterPro; IPR045225; Uracil/uridine/allantoin_perm.
DR   PANTHER; PTHR30618:SF4; -; 1.
DR   PANTHER; PTHR30618; NCS1 FAMILY PURINE/PYRIMIDINE TRANSPORTER; 1.
DR   Pfam; PF02133; Transp_cyt_pur; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000078397};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        36..53
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        73..96
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        108..128
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        166..185
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        192..217
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        237..260
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        272..296
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        327..349
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        370..392
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        398..416
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        477..500
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   554 AA;  60846 MW;  2BEB32084C920E24 CRC64;
     MSSLLRKLEV PHPENMPRPT ALLNHDVKPI EKERRVWGWP AFIALWSTVA FNMSNFQLGS
     SMLALGLNWW QAFLTMLFGH LLGAVLIVFV SVPGLYYRIS FPVATRIAWG YCGSIFVVLN
     RIVLSIVWCG VQSWQGGLMA YVCLRAIWPS IDNIKNTIPS STGMTLPQFI GFIVFFIIQF
     PFLFLSPRPL KYLVYVGSVG GFLAQLVLCI WACATMGSGG FGSVLQPNKA ALPGSQLGWM
     CVYSITATMS SITSGTVSVC DYARFAKQPS SGIWSQLLGF FPGWLSNVFG TLTIAATQRR
     YGSELWSVAS LLIAVQDANP DSKTRTAVVF AALPFALSQI SLNIIGNTFS GGTDMASLVP
     KYINIRRGQI ATALLGLVIN PWYLLSGAVI FISVMSAYTV FLQPFLGIIV AHYFIVQKCR
     IKVSDLYCFG SRSIYWYTAG VNWRSIVAWT CGAAPHIPGF LTTVRPSIQV PLGASHLYYL
     SSFTGFLIPF ALTIILHLVF PVASQTAYTS SGTMDQSIQE LEDYIDRLDV DFGLIQGVAS
     PAAEKLEDAF DGEK
//