ID A0A179G7L6_METCM Unreviewed; 275 AA.
AC A0A179G7L6;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=Defective in cullin neddylation protein {ECO:0000256|RuleBase:RU410713};
GN ORFNames=VFPPC_13020 {ECO:0000313|EMBL:OAQ73500.1};
OS Pochonia chlamydosporia 170.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Clavicipitaceae; Pochonia.
OX NCBI_TaxID=1380566 {ECO:0000313|EMBL:OAQ73500.1, ECO:0000313|Proteomes:UP000078397};
RN [1] {ECO:0000313|EMBL:OAQ73500.1, ECO:0000313|Proteomes:UP000078397}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=170 {ECO:0000313|EMBL:OAQ73500.1};
RX PubMed=27416025;
RA Wang G., Liu Z., Lin R., Li E., Mao Z., Ling J., Yang Y., Yin W.B., Xie B.;
RT "Biosynthesis of antibiotic leucinostatins in bio-control fungus
RT Purpureocillium lilacinum and their inhibition on phytophthora revealed by
RT genome mining.";
RL PLoS Pathog. 12:E1005685-E1005685(2016).
CC -!- FUNCTION: Neddylation of cullins play an essential role in the
CC regulation of SCF-type complexes activity.
CC {ECO:0000256|RuleBase:RU410713}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OAQ73500.1}.
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DR EMBL; LSBJ02000001; OAQ73500.1; -; Genomic_DNA.
DR RefSeq; XP_018149583.1; XM_018290797.1.
DR AlphaFoldDB; A0A179G7L6; -.
DR STRING; 1380566.A0A179G7L6; -.
DR GeneID; 28854791; -.
DR KEGG; pchm:VFPPC_13020; -.
DR OrthoDB; 169757at2759; -.
DR Proteomes; UP000078397; Chromosome 1.
DR Gene3D; 1.10.238.200; Cullin, PONY binding domain; 1.
DR Gene3D; 1.10.8.10; DNA helicase RuvA subunit, C-terminal domain; 1.
DR Gene3D; 1.10.238.10; EF-hand; 1.
DR InterPro; IPR014764; DCN-prot.
DR InterPro; IPR042460; DCN1-like_PONY.
DR InterPro; IPR005176; PONY_dom.
DR InterPro; IPR009060; UBA-like_sf.
DR PANTHER; PTHR12281:SF31; DCN1-LIKE PROTEIN 3; 1.
DR PANTHER; PTHR12281; RP42 RELATED; 1.
DR Pfam; PF03556; Cullin_binding; 1.
DR Pfam; PF14555; UBA_4; 1.
DR SUPFAM; SSF46934; UBA-like; 1.
DR PROSITE; PS51229; DCUN1; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000078397};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786}.
FT DOMAIN 57..260
FT /note="DCUN1"
FT /evidence="ECO:0000259|PROSITE:PS51229"
SQ SEQUENCE 275 AA; 31122 MW; 9C12EBE98DEA804B CRC64;
MPPPSSAQQK VLTAQFVNLT GATERQATKY LKSTGYKINE AVDAFYSSGN EVKGPSPVES
KLDALFDTLR DDKNDEKDKM ELESTMDYLG SKLNVSLENA ELFVVLEIVQ APSVGEITRQ
GYVEGWKKAN AGTTHQEHSR YVQRLLSTLS KNPAVFKKVY RYTFVAGREG DQKSLSLENA
LIYWGMLFSP PGMAWKTENH DWLDLWKTFL NEKWTRSVNK DMWNMVLEFA VKTLADDSLS
FWSEDGAWPS VIDDFVEWCL KKGIGKSETM DVDAA
//
