ID A0A179G8M3_METCM Unreviewed; 1070 AA.
AC A0A179G8M3;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Sulfite reductase flavoprotein component {ECO:0000313|EMBL:OAQ73771.1};
GN ORFNames=VFPPC_01403 {ECO:0000313|EMBL:OAQ73771.1};
OS Pochonia chlamydosporia 170.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Clavicipitaceae; Pochonia.
OX NCBI_TaxID=1380566 {ECO:0000313|EMBL:OAQ73771.1, ECO:0000313|Proteomes:UP000078397};
RN [1] {ECO:0000313|EMBL:OAQ73771.1, ECO:0000313|Proteomes:UP000078397}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=170 {ECO:0000313|EMBL:OAQ73771.1};
RX PubMed=27416025;
RA Wang G., Liu Z., Lin R., Li E., Mao Z., Ling J., Yang Y., Yin W.B., Xie B.;
RT "Biosynthesis of antibiotic leucinostatins in bio-control fungus
RT Purpureocillium lilacinum and their inhibition on phytophthora revealed by
RT genome mining.";
RL PLoS Pathog. 12:E1005685-E1005685(2016).
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OAQ73771.1}.
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DR EMBL; LSBJ02000001; OAQ73771.1; -; Genomic_DNA.
DR RefSeq; XP_018149854.1; XM_018281238.1.
DR AlphaFoldDB; A0A179G8M3; -.
DR STRING; 1380566.A0A179G8M3; -.
DR GeneID; 28845232; -.
DR KEGG; pchm:VFPPC_01403; -.
DR OrthoDB; 5488444at2759; -.
DR Proteomes; UP000078397; Chromosome 1.
DR GO; GO:0016903; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors; IEA:InterPro.
DR CDD; cd06207; CyPoR_like; 1.
DR Gene3D; 3.40.50.920; -; 1.
DR Gene3D; 3.40.50.80; Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module; 1.
DR Gene3D; 3.40.920.10; Pyruvate-ferredoxin oxidoreductase, PFOR, domain III; 1.
DR Gene3D; 2.40.30.10; Translation factors; 1.
DR InterPro; IPR003097; CysJ-like_FAD-binding.
DR InterPro; IPR017927; FAD-bd_FR_type.
DR InterPro; IPR001709; Flavoprot_Pyr_Nucl_cyt_Rdtase.
DR InterPro; IPR039261; FNR_nucleotide-bd.
DR InterPro; IPR023173; NADPH_Cyt_P450_Rdtase_alpha.
DR InterPro; IPR001433; OxRdtase_FAD/NAD-bd.
DR InterPro; IPR033412; PFOR_II.
DR InterPro; IPR019752; Pyrv/ketoisovalerate_OxRed_cat.
DR InterPro; IPR002869; Pyrv_flavodox_OxRed_cen.
DR InterPro; IPR017938; Riboflavin_synthase-like_b-brl.
DR InterPro; IPR009014; Transketo_C/PFOR_II.
DR PANTHER; PTHR19384; NITRIC OXIDE SYNTHASE-RELATED; 1.
DR PANTHER; PTHR19384:SF109; SULFITE REDUCTASE [NADPH] FLAVOPROTEIN COMPONENT; 1.
DR Pfam; PF00667; FAD_binding_1; 1.
DR Pfam; PF00175; NAD_binding_1; 1.
DR Pfam; PF17147; PFOR_II; 1.
DR Pfam; PF01558; POR; 1.
DR PRINTS; PR00371; FPNCR.
DR SUPFAM; SSF52343; Ferredoxin reductase-like, C-terminal NADP-linked domain; 1.
DR SUPFAM; SSF53323; Pyruvate-ferredoxin oxidoreductase, PFOR, domain III; 1.
DR SUPFAM; SSF63380; Riboflavin synthase domain-like; 1.
DR SUPFAM; SSF52922; TK C-terminal domain-like; 1.
DR PROSITE; PS51384; FAD_FR; 1.
PE 4: Predicted;
KW FAD {ECO:0000256|ARBA:ARBA00022827};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000078397}.
FT DOMAIN 683..920
FT /note="FAD-binding FR-type"
FT /evidence="ECO:0000259|PROSITE:PS51384"
SQ SEQUENCE 1070 AA; 117534 MW; 663274963108FDBC CRC64;
MHSQPQESSG GAAAPQKTNS SDFEMLSSTL PFGQSVPLDT ISGTTYVTAQ LLVQQIAYKL
SDKIFSYSPE TFDLDIAAKN WAAKQNTNIH GYTPQVLPLQ TRTGAGSLAL GYIFSPDFDV
SKRHIPQTLL APSGSLQQLR GTLDQLSLLY SVSSPFVAHI AAADYTDLDG LVPNYDTVLR
LVEDLGLGLV GSSSTYEAQH MSLFSTLLAT VLPTLHVYDG IRVARETLRV ADALSESGVA
DLYNKLVAEA SKLNTHLDNA GKVVDLLKLF NDELGTVYQP FEYHGHETPD VVLVAFGSVE
TQVAKQTLNK IAGEGAKVGV INVRVYRPFI EEEFLKAIPA STRAIAVLGQ VRDRVAVEDD
ATQSALYGDV LTAITFSGKF DEEPKVLDIK YTPSQTLTPQ GLANTLHKVF GNEDEAKPLP
SLVNAEQYTF WDVDNSAALN SPAIIGNILS KQSTTNVYVH ATYDNLTQGG VVRTDVRASK
KALEAPYDVY EADVVVVGDD RILKEVDVVE SVADGGKIIL KLPNFKVEDV EKRLSVAFRK
AVQEKDIQLF ALDTSFSPAF EKDAQSKLLL ELAFLKIAQP ALSPETIGKL VLVEGHPPTL
EECVEAVNQC LSKIEVPATW AEVEADFQAP QLPISLQSNS FVSFQKEEVE EVLELGDWQA
AAKGLVFKEA YETQTALRPD LPVKTATISV KENRRLTPSD YDRNIFHIEF DLGDSGLTYK
IGEALGVHAE NDEEEVARFI QSYGLNPAEL VRVPAREDPE ALEIRTVHQA LIQNVDILGK
PPKRFYEALA EFATDETEQK KLEALGTSAG AEEFKRRSEV DMLTYVDILD EFKSARPGFN
DLIKIVSPLK RREYSIASAQ AVTPNSVALM IVVVDWVDTK GRTRYGHASH YLSRLQPGAI
VTASVKPSVM KLPTNDTAPL IMAGLGTGLA PFRAFVQYRA MQKAQGKDIG AILLYLGSRH
QREEYLYGEE WEAYLAAGVV TLVGAAFSRD QPQKIYIQDR MRQTLGDIAK AYIQDQGSFY
LCGPTWPVPD VTKVLEEAIA ADAKANGKKI DPKKEIEKLK EEGRYVLEVY
//
