ID A0A179G9A7_METCM Unreviewed; 580 AA.
AC A0A179G9A7;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE RecName: Full=DUF21 and CBS domain-containing protein (Mam3) {ECO:0008006|Google:ProtNLM};
GN ORFNames=VFPPC_01564 {ECO:0000313|EMBL:OAQ73963.1};
OS Pochonia chlamydosporia 170.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Clavicipitaceae; Pochonia.
OX NCBI_TaxID=1380566 {ECO:0000313|EMBL:OAQ73963.1, ECO:0000313|Proteomes:UP000078397};
RN [1] {ECO:0000313|EMBL:OAQ73963.1, ECO:0000313|Proteomes:UP000078397}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=170 {ECO:0000313|EMBL:OAQ73963.1};
RX PubMed=27416025;
RA Wang G., Liu Z., Lin R., Li E., Mao Z., Ling J., Yang Y., Yin W.B., Xie B.;
RT "Biosynthesis of antibiotic leucinostatins in bio-control fungus
RT Purpureocillium lilacinum and their inhibition on phytophthora revealed by
RT genome mining.";
RL PLoS Pathog. 12:E1005685-E1005685(2016).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OAQ73963.1}.
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DR EMBL; LSBJ02000001; OAQ73963.1; -; Genomic_DNA.
DR RefSeq; XP_018150046.1; XM_018281364.1.
DR AlphaFoldDB; A0A179G9A7; -.
DR STRING; 1380566.A0A179G9A7; -.
DR GeneID; 28845358; -.
DR KEGG; pchm:VFPPC_01564; -.
DR OrthoDB; 248389at2759; -.
DR Proteomes; UP000078397; Chromosome 1.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0010960; P:magnesium ion homeostasis; IEA:InterPro.
DR CDD; cd04590; CBS_pair_CorC_HlyC_assoc; 1.
DR Gene3D; 3.10.580.10; CBS-domain; 1.
DR InterPro; IPR045095; ACDP.
DR InterPro; IPR000644; CBS_dom.
DR InterPro; IPR046342; CBS_dom_sf.
DR InterPro; IPR002550; CNNM.
DR InterPro; IPR044751; Ion_transp-like_CBS.
DR PANTHER; PTHR12064; METAL TRANSPORTER CNNM; 1.
DR PANTHER; PTHR12064:SF100; PROTEIN MAM3; 1.
DR Pfam; PF01595; CNNM; 1.
DR SUPFAM; SSF54631; CBS-domain pair; 1.
DR PROSITE; PS51371; CBS; 2.
DR PROSITE; PS51846; CNNM; 1.
PE 4: Predicted;
KW CBS domain {ECO:0000256|PROSITE-ProRule:PRU00703};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PROSITE-
KW ProRule:PRU01193}; Reference proteome {ECO:0000313|Proteomes:UP000078397};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|PROSITE-
KW ProRule:PRU01193};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989, ECO:0000256|PROSITE-
KW ProRule:PRU01193}.
FT TRANSMEM 12..34
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 54..77
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 112..133
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 139..158
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 49..234
FT /note="CNNM transmembrane"
FT /evidence="ECO:0000259|PROSITE:PS51846"
FT DOMAIN 253..315
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
FT DOMAIN 317..380
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
FT REGION 518..580
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 527..541
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 544..565
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 566..580
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 580 AA; 62191 MW; 8F71B7C5BDF6BEEA CRC64;
MQRNGGSGGF ASLRTCVLGM GRVLGVGLSS VAAAPVLQTK PHHDDDDFEA TPVWVLYVAS
MALVLLGGAF AGLTIALMGQ DSIYLQVVSG DPAEPQYKNA KRVLDLLNKG KHWVLVTLLL
ANVIVNESLP VVLDRTLGGG VAAVVGSTVL IVIFGEIVPQ SICVRYGLPI GGYMSKPVLI
LMYLMSPVAW PTAKLLDWIL GEDHGTVYKK SGLKTLVTLH KSLGELSERL NQDEVTIITA
VLDLKDKPVS EVMTPMTDVY TLAEDHILDE KTMDNILSSG YSRIPIYRSG NNTDFVGMLL
VKTLITYDPE DRIPVREIPL GAIVETRPET SCLDIINFFQ EGKSHMVLVS DHPGSDHGAL
GVVTLEDVIE ELIGEEIVDE SDVYVDVHKA IRRLTPAPRA RRIHAEAGAA AVGRKPGDGA
ALVDIAEHLE ASDPVVGSLG AMSDGAPERI PKMATFMRRR GSAGPDGKPD DRPVPFKASL
DEMKQQLRHL APSNRAANPR NTRTNVFKIK QGLSVTTFVA GDGNSKPLDE PAHKPDDAAD
GDESTPLLNS TGVNGGQSEN GYGSGKSKSD KAKSKSPERQ
//
