ID A0A179H4K6_PURLI Unreviewed; 299 AA.
AC A0A179H4K6;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=Osmosensor, Mos1 {ECO:0000313|EMBL:OAQ85114.1};
DE SubName: Full=Transmembrane osmosensor {ECO:0000313|EMBL:GJN69356.1};
GN ORFNames=PCL_02464 {ECO:0000313|EMBL:PWI68063.1}, PLICBS_003404
GN {ECO:0000313|EMBL:GJN69356.1}, VFPBJ_03887
GN {ECO:0000313|EMBL:OAQ85114.1}, VFPFJ_06073
GN {ECO:0000313|EMBL:OAQ89659.1};
OS Purpureocillium lilacinum (Paecilomyces lilacinus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Ophiocordycipitaceae; Purpureocillium.
OX NCBI_TaxID=33203 {ECO:0000313|EMBL:OAQ85114.1, ECO:0000313|Proteomes:UP000078240};
RN [1] {ECO:0000313|EMBL:PWI68063.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=36-1 {ECO:0000313|EMBL:PWI68063.1};
RA Wang D.B., Wang M.;
RL Submitted (MAY-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:PWI68063.1, ECO:0000313|Proteomes:UP000245956}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=36-1 {ECO:0000313|EMBL:PWI68063.1,
RC ECO:0000313|Proteomes:UP000245956};
RX PubMed=27486440; DOI=10.3389/fmicb.2016.01084;
RA Xie J., Li S., Mo C., Xiao X., Peng D., Wang G., Xiao Y.;
RT "Genome and transcriptome sequences reveal the specific parasitism of the
RT nematophagous Purpureocillium lilacinum 36-1.";
RL Front. Microbiol. 7:1084-1084(2016).
RN [3] {ECO:0000313|EMBL:OAQ85114.1, ECO:0000313|Proteomes:UP000078240}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PLBJ-1 {ECO:0000313|EMBL:OAQ85114.1}, and PLFJ-1
RC {ECO:0000313|EMBL:OAQ89659.1};
RA Wang G., Liu Z., Lin R., Li E., Mao Z., Ling J., Yin W., Xie B.;
RT "Biosynthesis of antibiotic leucinostatins and their inhibition on
RT Phytophthora in bio-control Purpureocillium lilacinum.";
RL Submitted (JAN-2016) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|EMBL:GJN69356.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=CBS 284.36 {ECO:0000313|EMBL:GJN69356.1};
RA Alimu Y., Kusuya Y., Yamamoto T., Shigemune N., Takahashi H., Yaguchi T.;
RT "Tolerabce induction of polyhexamethylene biguanide on Purpureocillium
RT lilacinum strains.";
RL Submitted (DEC-2021) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBUNIT: Forms homooligomers. {ECO:0000256|ARBA:ARBA00011175}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the SHO1 family.
CC {ECO:0000256|ARBA:ARBA00009739}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OAQ85114.1}.
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DR EMBL; BQKW01000002; GJN69356.1; -; Genomic_DNA.
DR EMBL; LSBH01000002; OAQ85114.1; -; Genomic_DNA.
DR EMBL; LSBI01000005; OAQ89659.1; -; Genomic_DNA.
DR EMBL; LCWV01000016; PWI68063.1; -; Genomic_DNA.
DR RefSeq; XP_018178378.1; XM_018323148.1.
DR STRING; 33203.A0A179H4K6; -.
DR GeneID; 28888197; -.
DR KEGG; plj:VFPFJ_06073; -.
DR OMA; NIIGDPF; -.
DR OrthoDB; 1365981at2759; -.
DR Proteomes; UP000078240; Unassembled WGS sequence.
DR Proteomes; UP000078340; Unassembled WGS sequence.
DR Proteomes; UP000245956; Unassembled WGS sequence.
DR Proteomes; UP001056679; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR CDD; cd11855; SH3_Sho1p; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR InterPro; IPR035522; Sho1_SH3.
DR PANTHER; PTHR15735; FCH AND DOUBLE SH3 DOMAINS PROTEIN; 1.
DR PANTHER; PTHR15735:SF20; PROTEIN NERVOUS WRECK; 1.
DR Pfam; PF00018; SH3_1; 1.
DR PRINTS; PR00452; SH3DOMAIN.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS50002; SH3; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000078340};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}; Stress response {ECO:0000256|ARBA:ARBA00023016};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 21..45
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 57..77
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 84..104
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 116..136
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 240..299
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 161..239
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 161..232
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 299 AA; 32032 MW; 598E6E3FC4B0D398 CRC64;
MEHSRSYGRK GVQLGNILGD PFALATISIS LLAWFITFIS CIVSQIQATP DDKFPTFAWW
AVVYSLFLII GVFVVVASDA VHTYHVAVTG YLSGGMVLVT SSVNSLVYSK SGAREAAAAG
FILLSMVVIV WIFYFGSTPS STPRAFLDSF ALAKESSTSH GQAMNGYGGT GRPETSNSVQ
PPQMYTSAQL NGFENPSPVG GASQANGGRT SAIPSAFGNT SLPQSQPTTK PDAEVVPPTE
YPYRAKAIYS YEANPDDANE ISFSKHEILE VSDVSGRWWQ ARKESGETGI APSNYLILL
//
