ID A0A179HAA8_PURLI Unreviewed; 1051 AA.
AC A0A179HAA8;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Cytoskeleton assembly control protein Sla2 {ECO:0000313|EMBL:OAQ86461.1};
DE SubName: Full=Sla2 Src-like adaptor 2 {ECO:0000313|EMBL:GJN67297.1};
GN ORFNames=PLICBS_001321 {ECO:0000313|EMBL:GJN67297.1}, VFPBJ_00501
GN {ECO:0000313|EMBL:OAQ86461.1}, VFPFJ_00533
GN {ECO:0000313|EMBL:OAQ94424.1};
OS Purpureocillium lilacinum (Paecilomyces lilacinus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Ophiocordycipitaceae; Purpureocillium.
OX NCBI_TaxID=33203 {ECO:0000313|EMBL:OAQ86461.1, ECO:0000313|Proteomes:UP000078240};
RN [1] {ECO:0000313|EMBL:OAQ86461.1, ECO:0000313|Proteomes:UP000078240}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PLBJ-1 {ECO:0000313|EMBL:OAQ86461.1}, and PLFJ-1
RC {ECO:0000313|EMBL:OAQ94424.1};
RA Wang G., Liu Z., Lin R., Li E., Mao Z., Ling J., Yin W., Xie B.;
RT "Biosynthesis of antibiotic leucinostatins and their inhibition on
RT Phytophthora in bio-control Purpureocillium lilacinum.";
RL Submitted (JAN-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:GJN67297.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=CBS 284.36 {ECO:0000313|EMBL:GJN67297.1};
RA Alimu Y., Kusuya Y., Yamamoto T., Shigemune N., Takahashi H., Yaguchi T.;
RT "Tolerabce induction of polyhexamethylene biguanide on Purpureocillium
RT lilacinum strains.";
RL Submitted (DEC-2021) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the SLA2 family.
CC {ECO:0000256|ARBA:ARBA00010135}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OAQ86461.1}.
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DR EMBL; BQKW01000001; GJN67297.1; -; Genomic_DNA.
DR EMBL; LSBH01000001; OAQ86461.1; -; Genomic_DNA.
DR EMBL; LSBI01000001; OAQ94424.1; -; Genomic_DNA.
DR RefSeq; XP_018183143.1; XM_018317618.1.
DR STRING; 33203.A0A179HAA8; -.
DR GeneID; 28882667; -.
DR KEGG; plj:VFPFJ_00533; -.
DR OMA; NREMSDL; -.
DR OrthoDB; 7775at2759; -.
DR Proteomes; UP000078240; Unassembled WGS sequence.
DR Proteomes; UP000078340; Unassembled WGS sequence.
DR Proteomes; UP001056679; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR GO; GO:0030276; F:clathrin binding; IEA:InterPro.
DR GO; GO:0005543; F:phospholipid binding; IEA:InterPro.
DR GO; GO:0006897; P:endocytosis; IEA:InterPro.
DR CDD; cd17007; ANTH_N_Sla2p; 1.
DR Gene3D; 1.25.40.90; -; 1.
DR Gene3D; 1.20.1410.10; I/LWEQ domain; 1.
DR InterPro; IPR011417; ANTH_dom.
DR InterPro; IPR013809; ENTH.
DR InterPro; IPR008942; ENTH_VHS.
DR InterPro; IPR035964; I/LWEQ_dom_sf.
DR InterPro; IPR002558; ILWEQ_dom.
DR InterPro; IPR030224; Sla2_fam.
DR PANTHER; PTHR10407; HUNTINGTIN INTERACTING PROTEIN 1; 1.
DR PANTHER; PTHR10407:SF15; HUNTINGTIN INTERACTING PROTEIN 1; 1.
DR Pfam; PF07651; ANTH; 1.
DR Pfam; PF01608; I_LWEQ; 1.
DR SMART; SM00273; ENTH; 1.
DR SMART; SM00307; ILWEQ; 1.
DR SUPFAM; SSF48464; ENTH/VHS domain; 1.
DR SUPFAM; SSF109885; I/LWEQ domain; 1.
DR PROSITE; PS50942; ENTH; 1.
DR PROSITE; PS50945; I_LWEQ; 1.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Reference proteome {ECO:0000313|Proteomes:UP000078340}.
FT DOMAIN 8..137
FT /note="ENTH"
FT /evidence="ECO:0000259|PROSITE:PS50942"
FT DOMAIN 809..1051
FT /note="I/LWEQ"
FT /evidence="ECO:0000259|PROSITE:PS50945"
FT REGION 279..305
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 337..360
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 1010..1037
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 289..305
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 344..360
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1051 AA; 118843 MW; E9E8AD9142B2F0F7 CRC64;
MTSLRTTEHT KTDQELAISI KKATNSDEIS PKRKHVRACI VYTWDHRSAQ AFWSGIKVQP
ILADEVQTFK ALITIHKVLQ EGHPSAIKDA MANRSWIDGL NRGMTGEGIR GYGPLIREYV
YYLLAKLSFH QQHPEFNGTF EYEEYLSLKA INDPNEGYET ITDLMVLQDK IEQFQKLIFS
HFRNVGNNEC RISALVPLVQ ESYGIYKFIT SMLRAMHSIT GDDEALQPLR QRYDAQHYRL
VKFYYECSNL RYLTSLITIP KLPQDPPNLL AEDDEAPALP ARPKQEIERQ PTPPVEPKSE
EPDEISEFWK SELDRQNREY EEQQRVLEER QQAALLAQQR AQQDAQREFE EQQRRLAEQQ
QRDQEALLAQ QAQWQTQGRL AELERENLNA RAQYENDQLM LQQYDHRVKA LEGELAQIQN
SFGQQITSKD DQIRALQEQV NTWRTKYESL AKLYSQLRHE HLDLLQKFKS VQLKAASAQE
AIDKREKLER EIKTKNLELA DMIRERDRAL HDKDRLNGSN KDEVERLKRE LRMAQDKADN
LERSKGNELS TMLAKYNREM SDLEEALRNK SRALDDAHSK LRDGSSDLEQ LLREKEEELE
VYKAGMDQTL IELNDLKQNQ GETDHALDGQ IDALILSNLD KINDIIDSVL QAGVSRVDDA
LYELDSSMQA GNQNASPSYV LSQIEKASAS AMEFATSFNN FIADGPNSTH ADVIKAINVF
AGAIADVCSN TKGLTRLATD DKKTDSLMNG ARLSAQSTVQ FFRGLQSFRL EGMDPLQKTD
VVINSNNDVQ MNLQKLNKLA ESFAPGFGKL ANNKGDLGDL VDSELSKAAD AIAAAAARLA
KLKNKPRDGY STYEVKVHDS ILDAATAITN AIAELIKAAT LTQQEIVQAG RGSSSRTAFY
KKNNRWTEGL ISAAKAVASS TNTLIETADG VLSNRNSPEQ LIVASNDVAA STAQLVAASR
VKAGFMSKSQ DRLEQASKAV GAACRALVRQ VQSMIKERSQ DEEQVDYAKL GAHEFKVREM
EQQVEILQLE NALASARHRL GEMRKISYQE E
//
