ID A0A179HFB3_PURLI Unreviewed; 472 AA.
AC A0A179HFB3;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Glutamate 5-kinase {ECO:0000313|EMBL:OAQ89076.1};
GN ORFNames=PLICBS_002854 {ECO:0000313|EMBL:GJN68809.1}, VFPBJ_03309
GN {ECO:0000313|EMBL:OAQ84541.1}, VFPFJ_05485
GN {ECO:0000313|EMBL:OAQ89076.1};
OS Purpureocillium lilacinum (Paecilomyces lilacinus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Ophiocordycipitaceae; Purpureocillium.
OX NCBI_TaxID=33203 {ECO:0000313|EMBL:OAQ89076.1, ECO:0000313|Proteomes:UP000078340};
RN [1] {ECO:0000313|EMBL:OAQ89076.1, ECO:0000313|Proteomes:UP000078340}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PLBJ-1 {ECO:0000313|EMBL:OAQ84541.1}, and PLFJ-1
RC {ECO:0000313|EMBL:OAQ89076.1};
RA Wang G., Liu Z., Lin R., Li E., Mao Z., Ling J., Yin W., Xie B.;
RT "Biosynthesis of antibiotic leucinostatins and their inhibition on
RT Phytophthora in bio-control Purpureocillium lilacinum.";
RL Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:GJN68809.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=CBS 284.36 {ECO:0000313|EMBL:GJN68809.1};
RA Alimu Y., Kusuya Y., Yamamoto T., Shigemune N., Takahashi H., Yaguchi T.;
RT "Tolerabce induction of polyhexamethylene biguanide on Purpureocillium
RT lilacinum strains.";
RL Submitted (DEC-2021) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OAQ89076.1}.
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DR EMBL; BQKW01000002; GJN68809.1; -; Genomic_DNA.
DR EMBL; LSBH01000002; OAQ84541.1; -; Genomic_DNA.
DR EMBL; LSBI01000005; OAQ89076.1; -; Genomic_DNA.
DR RefSeq; XP_018177795.1; XM_018322565.1.
DR STRING; 33203.A0A179HFB3; -.
DR GeneID; 28887614; -.
DR KEGG; plj:VFPFJ_05485; -.
DR OMA; NLAFPPH; -.
DR OrthoDB; 2021096at2759; -.
DR Proteomes; UP000078240; Unassembled WGS sequence.
DR Proteomes; UP000078340; Unassembled WGS sequence.
DR Proteomes; UP001056679; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004349; F:glutamate 5-kinase activity; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR GO; GO:0006561; P:proline biosynthetic process; IEA:UniProtKB-KW.
DR CDD; cd04242; AAK_G5K_ProB; 1.
DR CDD; cd21157; PUA_G5K; 1.
DR Gene3D; 3.40.1160.10; Acetylglutamate kinase-like; 2.
DR Gene3D; 2.30.130.10; PUA domain; 1.
DR HAMAP; MF_00456; ProB; 1.
DR InterPro; IPR036393; AceGlu_kinase-like_sf.
DR InterPro; IPR001048; Asp/Glu/Uridylate_kinase.
DR InterPro; IPR041739; G5K_ProB.
DR InterPro; IPR001057; Glu/AcGlu_kinase.
DR InterPro; IPR011529; Glu_5kinase.
DR InterPro; IPR005715; Glu_5kinase/COase_Synthase.
DR InterPro; IPR019797; Glutamate_5-kinase_CS.
DR InterPro; IPR002478; PUA.
DR InterPro; IPR015947; PUA-like_sf.
DR InterPro; IPR036974; PUA_sf.
DR NCBIfam; TIGR01027; proB; 1.
DR PANTHER; PTHR43654; GLUTAMATE 5-KINASE; 1.
DR PANTHER; PTHR43654:SF3; GLUTAMATE 5-KINASE; 1.
DR Pfam; PF00696; AA_kinase; 1.
DR Pfam; PF01472; PUA; 1.
DR PIRSF; PIRSF000729; GK; 2.
DR PRINTS; PR00474; GLU5KINASE.
DR SMART; SM00359; PUA; 1.
DR SUPFAM; SSF53633; Carbamate kinase-like; 1.
DR SUPFAM; SSF88697; PUA domain-like; 1.
DR PROSITE; PS00902; GLUTAMATE_5_KINASE; 1.
DR PROSITE; PS50890; PUA; 1.
PE 3: Inferred from homology;
KW Amino-acid biosynthesis {ECO:0000256|ARBA:ARBA00022605};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:OAQ89076.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Proline biosynthesis {ECO:0000256|ARBA:ARBA00022650};
KW Reference proteome {ECO:0000313|Proteomes:UP000078340};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 352..450
FT /note="PUA"
FT /evidence="ECO:0000259|SMART:SM00359"
FT REGION 1..29
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 472 AA; 51323 MW; 55A176AACB890AB9 CRC64;
MTDEGITSGR ATPQPQQQQQ QQQAQAADMT KRSKSYTVVI KLGTSSIVDE KTHEPLLPIL
TLIVDTACKL RKDGHRVVIV SSGAIGVGLR RMDVDKRPKH LAQLQALAAI GQCRLIGLWD
SLFAHMAQPV AQILLTRNDI ADRTRYLNAQ NTFNQLMDMG VIPIVNENDT LAVSEIKFGD
NDTLSAITAA MIHADMLFLM TDVDCLYDKN PRTHPDARPI EIVDDINALE ADVSSAGSAL
GTGGMGTKIV AARLGMLAGV TTIITRSSNP GNILGIVRYL TTPRTPSSST SSESGDHAAD
HITQKTVSLN LSDASTHFDE TEAPPLHTRF LPSSDPIQDR YFWLLHTPNP HGTVYIDAGC
HRALIDKAGL LPVGVVDVEG HFAQSEVVRL VVVERRASSP GPDGKRWEGF AQEVGRIIVN
YAAAEISMIM GHKSSQIESI LGYADSEYVA DRSHIGFFRP ESRPVTPIRD LS
//
