ID A0A179HM26_PURLI Unreviewed; 847 AA.
AC A0A179HM26;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=CorA family metal ion transporter {ECO:0000313|EMBL:OAQ91054.1};
DE SubName: Full=CorA metal ion transporter {ECO:0000313|EMBL:GJN68558.1};
GN ORFNames=PLICBS_002601 {ECO:0000313|EMBL:GJN68558.1}, VFPFJ_05213
GN {ECO:0000313|EMBL:OAQ91054.1};
OS Purpureocillium lilacinum (Paecilomyces lilacinus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Ophiocordycipitaceae; Purpureocillium.
OX NCBI_TaxID=33203 {ECO:0000313|EMBL:OAQ91054.1, ECO:0000313|Proteomes:UP000078340};
RN [1] {ECO:0000313|EMBL:OAQ91054.1, ECO:0000313|Proteomes:UP000078340}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PLFJ-1 {ECO:0000313|EMBL:OAQ91054.1};
RA Wang G., Liu Z., Lin R., Li E., Mao Z., Ling J., Yin W., Xie B.;
RT "Biosynthesis of antibiotic leucinostatins and their inhibition on
RT Phytophthora in bio-control Purpureocillium lilacinum.";
RL Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:GJN68558.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=CBS 284.36 {ECO:0000313|EMBL:GJN68558.1};
RA Alimu Y., Kusuya Y., Yamamoto T., Shigemune N., Takahashi H., Yaguchi T.;
RT "Tolerabce induction of polyhexamethylene biguanide on Purpureocillium
RT lilacinum strains.";
RL Submitted (DEC-2021) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35)
CC family. {ECO:0000256|ARBA:ARBA00009765}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OAQ91054.1}.
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DR EMBL; BQKW01000002; GJN68558.1; -; Genomic_DNA.
DR EMBL; LSBI01000004; OAQ91054.1; -; Genomic_DNA.
DR RefSeq; XP_018179773.1; XM_018322293.1.
DR AlphaFoldDB; A0A179HM26; -.
DR STRING; 33203.A0A179HM26; -.
DR GeneID; 28887342; -.
DR KEGG; plj:VFPFJ_05213; -.
DR OMA; TNANHNT; -.
DR OrthoDB; 1358357at2759; -.
DR Proteomes; UP000078340; Unassembled WGS sequence.
DR Proteomes; UP001056679; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015095; F:magnesium ion transmembrane transporter activity; IEA:InterPro.
DR CDD; cd12829; Alr1p-like; 1.
DR Gene3D; 3.30.460.20; CorA soluble domain-like; 1.
DR Gene3D; 1.20.58.340; Magnesium transport protein CorA, transmembrane region; 2.
DR InterPro; IPR044089; Alr1-like.
DR InterPro; IPR045861; CorA_cytoplasmic_dom.
DR InterPro; IPR045863; CorA_TM1_TM2.
DR InterPro; IPR002523; MgTranspt_CorA/ZnTranspt_ZntB.
DR PANTHER; PTHR21535; MAGNESIUM AND COBALT TRANSPORT PROTEIN/MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM8; 1.
DR PANTHER; PTHR21535:SF51; MANGANESE RESISTANCE PROTEIN MNR2; 1.
DR Pfam; PF01544; CorA; 1.
DR SUPFAM; SSF143865; CorA soluble domain-like; 1.
DR SUPFAM; SSF144083; Magnesium transport protein CorA, transmembrane region; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000078340};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 783..809
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 821..840
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 1..241
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 410..511
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 37..54
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 59..77
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 78..94
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 114..128
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 134..156
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 185..217
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 439..462
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 491..508
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 847 AA; 95303 MW; 36D4C5CCCA8AEAC6 CRC64;
MASNRFNALH PASRLGVEGQ SVAAGRAPPP TSVPVTAAPA ARQQQQQQQD QESGKSRAQP
RKRKGHRGGK KKRSRRKSFA ALAEDSHDEM QEASGEGFYK MPTGNLSGTS IDSEALLDHR
EHKPMRLRRP STVAATSPFH NPFSTPGASR LRSIHTPNSG DGERADETNP WDETAPLLSD
SARYRASPTG PSSYGAASRN RSRRSSSRSS RTKLTANLTV KDGYDVNHPP SVPGSPAFGG
VDRPELAFGD VMIRDEISLD GSPHGSLDAE EAMSEADGTV RDHRADLARR MTEAAGDVCF
PAPDMSELGD EDAHSRDVAA HQYRGRRRRA QWPDLSVLEE WRHFEKEDRS EEVRVKKITE
PQLINGRLRP VRKGWFQADE EAPYRFTYFN EEFQSTIHSQ TISELVQPGG GFRELFIPDP
RILSDSESDD DDDDEPSTGL RPQNSNGGDY DSRLSTRQPS LAESRRDGAM SPGHDPSAVS
GRATPIAIKS PEVTQKETQA TPHETTSTPR PVRYGDRPVW WLDVLCPTEA EMKVISKAFG
IHPLTAEDIM LQEAREKVEL FRHYYFVNYR TFEQDINSEN HLEPVNMYVV VFREGVLSFH
FSMTPHPANV RRRIRQLRDY LILSSDWISY AIIDDITDVF QPLIQNIEDE VDEIDDKILE
FHSSTDKRLK GEKPSKNDDS NTFVDSSDML RRVGDCRKRV MSLYRLLGNK ADVIKGFAKR
CNERWEVAPR SEIGLYLGDI QDHIITMTSN LGHYEKILAR SHGNYLAQIN IRMNERAEQT
NDVLGKLTVL GTIVLPMNII TGLWGMNVWV PGQEYEGDLQ WFFWITAGLL FFGLACFMIA
KRVYGIV
//
