ID A0A179HPZ6_PURLI Unreviewed; 670 AA.
AC A0A179HPZ6;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE RecName: Full=Endopolyphosphatase {ECO:0000256|ARBA:ARBA00014458, ECO:0000256|PIRNR:PIRNR027093};
DE EC=3.6.1.10 {ECO:0000256|ARBA:ARBA00012459, ECO:0000256|PIRNR:PIRNR027093};
GN ORFNames=PCL_09548 {ECO:0000313|EMBL:PWI64576.1}, PLICBS_007157
GN {ECO:0000313|EMBL:GJN73081.1}, VFPBJ_04286
GN {ECO:0000313|EMBL:OAQ81702.1}, VFPFJ_03488
GN {ECO:0000313|EMBL:OAQ91748.1};
OS Purpureocillium lilacinum (Paecilomyces lilacinus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Ophiocordycipitaceae; Purpureocillium.
OX NCBI_TaxID=33203 {ECO:0000313|EMBL:OAQ91748.1, ECO:0000313|Proteomes:UP000078340};
RN [1] {ECO:0000313|EMBL:PWI64576.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=36-1 {ECO:0000313|EMBL:PWI64576.1};
RA Wang D.B., Wang M.;
RL Submitted (MAY-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:PWI64576.1, ECO:0000313|Proteomes:UP000245956}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=36-1 {ECO:0000313|EMBL:PWI64576.1,
RC ECO:0000313|Proteomes:UP000245956};
RX PubMed=27486440; DOI=10.3389/fmicb.2016.01084;
RA Xie J., Li S., Mo C., Xiao X., Peng D., Wang G., Xiao Y.;
RT "Genome and transcriptome sequences reveal the specific parasitism of the
RT nematophagous Purpureocillium lilacinum 36-1.";
RL Front. Microbiol. 7:1084-1084(2016).
RN [3] {ECO:0000313|EMBL:OAQ91748.1, ECO:0000313|Proteomes:UP000078340}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PLBJ-1 {ECO:0000313|EMBL:OAQ81702.1}, and PLFJ-1
RC {ECO:0000313|EMBL:OAQ91748.1};
RA Wang G., Liu Z., Lin R., Li E., Mao Z., Ling J., Yin W., Xie B.;
RT "Biosynthesis of antibiotic leucinostatins and their inhibition on
RT Phytophthora in bio-control Purpureocillium lilacinum.";
RL Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|EMBL:GJN73081.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=CBS 284.36 {ECO:0000313|EMBL:GJN73081.1};
RA Alimu Y., Kusuya Y., Yamamoto T., Shigemune N., Takahashi H., Yaguchi T.;
RT "Tolerabce induction of polyhexamethylene biguanide on Purpureocillium
RT lilacinum strains.";
RL Submitted (DEC-2021) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Catalyzes the hydrolysis of inorganic polyphosphate (polyP)
CC chains of many hundreds of phosphate residues into shorter lengths.
CC {ECO:0000256|PIRNR:PIRNR027093}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=[phosphate](n+1) + n H2O = n H(+) + (n+1) phosphate;
CC Xref=Rhea:RHEA:22452, Rhea:RHEA-COMP:14280, ChEBI:CHEBI:15377,
CC ChEBI:CHEBI:15378, ChEBI:CHEBI:16838, ChEBI:CHEBI:43474; EC=3.6.1.10;
CC Evidence={ECO:0000256|PIRNR:PIRNR027093};
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004606}; Single-
CC pass type II membrane protein {ECO:0000256|ARBA:ARBA00004606}. Vacuole
CC membrane {ECO:0000256|ARBA:ARBA00004576}; Single-pass type II membrane
CC protein {ECO:0000256|ARBA:ARBA00004576}.
CC -!- SIMILARITY: Belongs to the endopolyphosphatase PPN1 family.
CC {ECO:0000256|ARBA:ARBA00010399}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OAQ91748.1}.
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DR EMBL; BQKW01000005; GJN73081.1; -; Genomic_DNA.
DR EMBL; LSBH01000003; OAQ81702.1; -; Genomic_DNA.
DR EMBL; LSBI01000003; OAQ91748.1; -; Genomic_DNA.
DR EMBL; LCWV01000054; PWI64576.1; -; Genomic_DNA.
DR RefSeq; XP_018180467.1; XM_018320570.1.
DR STRING; 33203.A0A179HPZ6; -.
DR GeneID; 28885619; -.
DR KEGG; plj:VFPFJ_03488; -.
DR OMA; WAERYSV; -.
DR OrthoDB; 1334224at2759; -.
DR Proteomes; UP000078240; Unassembled WGS sequence.
DR Proteomes; UP000078340; Unassembled WGS sequence.
DR Proteomes; UP000245956; Unassembled WGS sequence.
DR Proteomes; UP001056679; Unassembled WGS sequence.
DR GO; GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0000298; F:endopolyphosphatase activity; IEA:UniProtKB-EC.
DR Gene3D; 3.60.21.10; -; 1.
DR InterPro; IPR004843; Calcineurin-like_PHP_ApaH.
DR InterPro; IPR012358; EndopolyPtase_N1.
DR InterPro; IPR029052; Metallo-depent_PP-like.
DR PANTHER; PTHR10340:SF59; METALLOPHOS DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR10340; SPHINGOMYELIN PHOSPHODIESTERASE; 1.
DR Pfam; PF00149; Metallophos; 1.
DR PIRSF; PIRSF027093; EndopolyPtase_N1; 1.
DR SUPFAM; SSF56300; Metallo-dependent phosphatases; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PIRNR:PIRNR027093};
KW Membrane {ECO:0000256|PIRNR:PIRNR027093};
KW Reference proteome {ECO:0000313|Proteomes:UP000078340};
KW Signal {ECO:0000256|SAM:SignalP};
KW Signal-anchor {ECO:0000256|ARBA:ARBA00022968};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022968};
KW Vacuole {ECO:0000256|ARBA:ARBA00022554, ECO:0000256|PIRNR:PIRNR027093}.
FT SIGNAL 1..23
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 24..670
FT /note="Endopolyphosphatase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5010456050"
FT DOMAIN 56..321
FT /note="Calcineurin-like phosphoesterase"
FT /evidence="ECO:0000259|Pfam:PF00149"
FT REGION 449..514
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 547..570
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 618..644
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 466..482
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 670 AA; 76674 MW; B7E5D9A39AD031CB CRC64;
MARAAWMPLQ LLVALSGCIR LLASPTPPEY DALQRVLQPA RHPEARPQQQ RKLNGRFLHI
TDLHPDDFYK AHTSSEEGIA CHRGKGMAGT YGAEMTDCDS PFSLVNATFD WIEANIRDDI
DFVVWTGDSA RHDSDEKHPR TAEQVLDSNR RVADKFVEAF TSPRDSKLSI PVIPTFGNND
FLPHNIMEAG PNKWFHAYSD IWSRFVPEEQ RHSFAFGGWF YVEVIPAKLA VFSLNTMFFF
DRNAAVDGCA NPSEPGYKHM EWLRIQLQHL RDTGMKAILI GHVPPARTDS KQNWDETCWQ
RYTLWLQQYR DVVTASLFGH MNIDHFLLGD TRKVNLLADS EDASDRSRLD DGVSIQSKSD
YLMELRDEWS GLPGSAIKVQ EEDDEDLSAD KKGKKKKKKY KKIGGKYAER YQLSFVSPSV
VPNFFPTLRV YEYNITGLDS AAVWHDSFDQ RNPTSPQPWD EADWDDEEHH ELRRDVDAEG
KKHKKKKGRK GKKKPKKDPN LIVPEDPPKA SLPGPAYYPQ SLTLTGYTQY FANLTYINND
MQDVGLDGSK WRGGNPDNKS PKHSPPKPNK FKYEVEYSTF DDKIYKLKDL TVKSYLGLAY
RMGQKKTNSA DALVDDFDED DDDEVEQSIR GVEADGKGKK KKNRERNKAW LHFLGHAFVK
TVPKEDLETM
//
