ID A0A179SMB6_9BACI Unreviewed; 472 AA.
AC A0A179SMB6;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 24-JAN-2024, entry version 29.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=A6K24_13555 {ECO:0000313|EMBL:OAS82080.1};
OS Metabacillus litoralis.
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Metabacillus.
OX NCBI_TaxID=152268 {ECO:0000313|EMBL:OAS82080.1, ECO:0000313|Proteomes:UP000078534};
RN [1] {ECO:0000313|Proteomes:UP000078534}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C44 {ECO:0000313|Proteomes:UP000078534};
RA Lyu Z., Lyu W.;
RL Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OAS82080.1}.
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DR EMBL; LWSG01000046; OAS82080.1; -; Genomic_DNA.
DR RefSeq; WP_066340530.1; NZ_LWSG01000046.1.
DR AlphaFoldDB; A0A179SMB6; -.
DR STRING; 152268.A6K24_13555; -.
DR Proteomes; UP000078534; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd00130; PAS; 2.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 2.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013655; PAS_fold_3.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR NCBIfam; TIGR00229; sensory_box; 2.
DR PANTHER; PTHR43065:SF10; PEROXIDE STRESS-ACTIVATED HISTIDINE KINASE MAK3; 1.
DR PANTHER; PTHR43065; SENSOR HISTIDINE KINASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF08447; PAS_3; 2.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00086; PAC; 2.
DR SMART; SM00091; PAS; 2.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 2.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50113; PAC; 2.
DR PROSITE; PS50112; PAS; 2.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000078534};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT DOMAIN 31..74
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 78..130
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 131..201
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 204..257
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 270..472
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
SQ SEQUENCE 472 AA; 53994 MW; C0317CBB2D5DD558 CRC64;
MIIDSSIYEQ VFMQSRIPQI IFEDGFHHII INKAFYEFLG YTKEEWQELS IKDISHPDDY
ELDLDLFHEM VTGQRQYYQM EKRYFHKSGE VVWGSLNVSF INDPTQKQQC FLAQVLDITE
QKNLEKFLSK KEQKYRLLAE NSSDVINLHS MNGNFVYISP SIKQILGYDP EELIDKTPYT
IIHPEDISEV KKKHSEVLTN TDPVLTTYRA RKKDGMYIWI ESNMRSVLNE QTGESEGIIS
VSRDIGKRLE TDNLLRKSDK LAVVGQLAAA VAHEIRNPLT SVKGFMQLFS NTKECNEDFI
KIVLDELDRV EAIISEFLTM SRPHQDKFEL IKVDELLRQV IQLSQTQALL INKEINYTVI
TEIPVINGDA NSLKQVFINI IQNALDALDE KGSVTVELSA SESTLFIHII DNGCGIPEER
LTNIGEPFYS TKEKGTGLGL MTSFKIIENH KGKLKIESTV GEGTRVSISL PL
//
