ID A0A179U888_BLAGS Unreviewed; 1048 AA.
AC A0A179U888;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=Nuclear pore complex protein {ECO:0000256|RuleBase:RU365072};
GN ORFNames=BDBG_00235 {ECO:0000313|EMBL:OAT03528.1};
OS Blastomyces gilchristii (strain SLH14081) (Blastomyces dermatitidis).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Ajellomycetaceae; Blastomyces.
OX NCBI_TaxID=559298 {ECO:0000313|EMBL:OAT03528.1, ECO:0000313|Proteomes:UP000002038};
RN [1] {ECO:0000313|Proteomes:UP000002038}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SLH14081 {ECO:0000313|Proteomes:UP000002038};
RX PubMed=26439490; DOI=10.1371/journal.pgen.1005493;
RA Munoz J.F., Gauthier G.M., Desjardins C.A., Gallo J.E., Holder J.,
RA Sullivan T.D., Marty A.J., Carmen J.C., Chen Z., Ding L., Gujja S.,
RA Magrini V., Misas E., Mitreva M., Priest M., Saif S., Whiston E.A.,
RA Young S., Zeng Q., Goldman W.E., Mardis E.R., Taylor J.W., McEwen J.G.,
RA Clay O.K., Klein B.S., Cuomo C.A.;
RT "The dynamic genome and transcriptome of the human fungal pathogen
RT Blastomyces and close relative Emmonsia.";
RL PLoS Genet. 11:E1005493-E1005493(2015).
CC -!- FUNCTION: Functions as a component of the nuclear pore complex (NPC).
CC {ECO:0000256|RuleBase:RU365072}.
CC -!- SUBUNIT: Part of the nuclear pore complex (NPC).
CC {ECO:0000256|RuleBase:RU365072}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nuclear pore complex
CC {ECO:0000256|RuleBase:RU365072}. Nucleus membrane
CC {ECO:0000256|RuleBase:RU365072}.
CC -!- SIMILARITY: Belongs to the nucleoporin Nup84/Nup107 family.
CC {ECO:0000256|RuleBase:RU365072}.
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DR EMBL; GG657448; OAT03528.1; -; Genomic_DNA.
DR RefSeq; XP_002628989.1; XM_002628943.1.
DR AlphaFoldDB; A0A179U888; -.
DR STRING; 559298.A0A179U888; -.
DR GeneID; 8510750; -.
DR KEGG; bgh:BDBG_00235; -.
DR VEuPathDB; FungiDB:BDBG_00235; -.
DR OrthoDB; 2718743at2759; -.
DR Proteomes; UP000002038; Unassembled WGS sequence.
DR GO; GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005643; C:nuclear pore; IEA:UniProtKB-SubCell.
DR GO; GO:0017056; F:structural constituent of nuclear pore; IEA:UniProtKB-UniRule.
DR GO; GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR Gene3D; 1.10.3450.20; -; 1.
DR Gene3D; 1.20.190.50; -; 1.
DR InterPro; IPR007252; Nup84/Nup107.
DR PANTHER; PTHR13003:SF2; NUCLEAR PORE COMPLEX PROTEIN NUP107; 1.
DR PANTHER; PTHR13003; NUP107-RELATED; 1.
DR Pfam; PF04121; Nup84_Nup100; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|RuleBase:RU365072};
KW mRNA transport {ECO:0000256|ARBA:ARBA00022816};
KW Nuclear pore complex {ECO:0000256|RuleBase:RU365072};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU365072};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000002038};
KW Translocation {ECO:0000256|ARBA:ARBA00023010,
KW ECO:0000256|RuleBase:RU365072};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU365072}.
FT REGION 1..118
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 829..858
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..28
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 35..87
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 101..118
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 829..850
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1048 AA; 118468 MW; 22858988CA24B0AB CRC64;
MAPLTYSSGF PLSQHNGSAA TTQAPTSRLH DVEIIEIDDD DEEEEEEDSL EDELEDEDEE
EEDEEEDEEE DEEDDEDGEE DEEMTGTDSM EERSSDFEES DQDAITISSG PASPGLLTTS
DIQQVLNPLR NTADRVTSQI EAFAQSLNQF KQHARGARPG DPETFREACR LVQKYQKIAE
TAAKEISRNN NLRKVKQSAI NRGTGASQGP NRGKLDEQLR RWELEAETWE LFFHMLSIDD
PESRTRAQRA QQTVLQSLHR YSSDKDVWDK FLEADRFSLE NVVVLKWLEK TARSSPQDID
GLISELETQA ERGQGLWAHG WLYTKEAIKG AKRLRSWPQP LEPDDPGLTM SLLSVEKQEP
LVTQLDPDAV TRQQHGLQKQ DQFYEQAAWL TCWKMLRQGQ SWKKIQEWSH ERLENWRAIS
VCGTPAEDEN NAADSGLTRL MSCRSQEAWR SACLALANNP VTSNFEKAVY ALICGEAEPA
YAICQGWGDY IYVFFNRSIL ARYREFCKQF HRKLSFSPTT DMVLSLDPPA YDNILTFLDN
VRRNDRTAVE ARNPYRTIQA AILSKNYNSF FFHQANAVSK AASLSNKATL VPKTVIANVD
DASLIAARDE DAIRIISHLF LVLQSLGYVR SDSHFVQTAT VNVIGYINLL RKAGKLELIP
LYASLLPENT AHMVLGNVLI DIVEPEDRER QVTIMRRLNI NLSAIIECQW QLVTSQADAK
EDKTTTIRLK RSVIHQAKGP GRIGPIKKNL IGRRISHEDE YLIRCLEWHR YADDQLPNIC
PRGTHLYKRF MGAGRLAAAR ELFNRVRVDM VPGDITGLGH SPFQILANGS ENGFDEPTSP
MKSSPTKSPL KSGIPRRRPL SSNLRAELYL QSHTMRDLEC LIAAFDALET WAGQMDQYEH
LSDKQQTKEF RKTLQATIDT ITERIEPLCG DWLSYPTDDL EATELEFIKS TYLPEVILAY
HSALFFAGHT IGREVLTQCM MLSSVVASSP SLTNSFIASG RMCELVDALA LSSIAMMSAK
ESKLGKKLED GASLDIWKIK PQQDGELV
//
