ID A0A179UAM6_BLAGS Unreviewed; 501 AA.
AC A0A179UAM6;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 24-JAN-2024, entry version 24.
DE SubName: Full=Flavin dependent monooxygenase {ECO:0000313|EMBL:OAT04890.1};
GN ORFNames=BDBG_01375 {ECO:0000313|EMBL:OAT04890.1};
OS Blastomyces gilchristii (strain SLH14081) (Blastomyces dermatitidis).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Ajellomycetaceae; Blastomyces.
OX NCBI_TaxID=559298 {ECO:0000313|EMBL:OAT04890.1, ECO:0000313|Proteomes:UP000002038};
RN [1] {ECO:0000313|Proteomes:UP000002038}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SLH14081 {ECO:0000313|Proteomes:UP000002038};
RX PubMed=26439490; DOI=10.1371/journal.pgen.1005493;
RA Munoz J.F., Gauthier G.M., Desjardins C.A., Gallo J.E., Holder J.,
RA Sullivan T.D., Marty A.J., Carmen J.C., Chen Z., Ding L., Gujja S.,
RA Magrini V., Misas E., Mitreva M., Priest M., Saif S., Whiston E.A.,
RA Young S., Zeng Q., Goldman W.E., Mardis E.R., Taylor J.W., McEwen J.G.,
RA Clay O.K., Klein B.S., Cuomo C.A.;
RT "The dynamic genome and transcriptome of the human fungal pathogen
RT Blastomyces and close relative Emmonsia.";
RL PLoS Genet. 11:E1005493-E1005493(2015).
CC -!- SIMILARITY: Belongs to the FMO family. {ECO:0000256|ARBA:ARBA00009183}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; GG657449; OAT04890.1; -; Genomic_DNA.
DR RefSeq; XP_002628467.1; XM_002628421.1.
DR AlphaFoldDB; A0A179UAM6; -.
DR GeneID; 8510540; -.
DR KEGG; bgh:BDBG_01375; -.
DR VEuPathDB; FungiDB:BDBG_01375; -.
DR OrthoDB; 2453855at2759; -.
DR Proteomes; UP000002038; Unassembled WGS sequence.
DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR GO; GO:0004499; F:N,N-dimethylaniline monooxygenase activity; IEA:InterPro.
DR GO; GO:0050661; F:NADP binding; IEA:InterPro.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR000960; Flavin_mOase.
DR InterPro; IPR020946; Flavin_mOase-like.
DR PANTHER; PTHR23023; DIMETHYLANILINE MONOOXYGENASE; 1.
DR PANTHER; PTHR23023:SF266; FLAVIN-CONTAINING MONOOXYGENASE; 1.
DR Pfam; PF00743; FMO-like; 2.
DR Pfam; PF13450; NAD_binding_8; 1.
DR PIRSF; PIRSF000332; FMO; 3.
DR PRINTS; PR00370; FMOXYGENASE.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 2.
PE 3: Inferred from homology;
KW FAD {ECO:0000256|ARBA:ARBA00022827};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Monooxygenase {ECO:0000256|ARBA:ARBA00023033, ECO:0000313|EMBL:OAT04890.1};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000002038}.
FT REGION 76..95
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 79..95
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 501 AA; 56532 MW; 7CC9CC2BAE69CD4B CRC64;
MRALSSHPIR RVAIIGAGPS GLAAAKFLLA EKYFEKIDVF EQRSRVGGVW NYSTAADKKL
ASIDIPQTNA HLPAEEPIWH SSSGSSQSSD SAKSQGRKEA SFISPLYDDL ETNIPHTLMR
FSDKPFPTDT QLFPRFATVL QYIEEYGADV EHLIQFQVQV VDVRLDDARA GTWIVTRKHL
ETGAQEDDVY DAVVVANGHY NVPYIPSIAG ISEWNAAYPN VITHSKTYSS PVEFQDKKVI
VVGNSASGID IGAQISTTCR KPLLASARSP SYFATGAVDD KKEYPQIVEF LPPITHNRAV
RFENGEIEED VDAVLFCTGY LYSFPFLSSL KPPVVEDGSR TLHVYQQILY ADQPTLAFPV
LNQRVIPFPM AENQSAVIAR VWSGRLSLPS KQEMYQWEEA EIAARGPGKA FHVFKYPMDA
DYINALHEWA ASAERRPGLE NEGRGRDCTY WNEKDRWTRE RFTLIKKEFN MKGEQRHQCR
TLEDVGFDFE AWKAEQSITY R
//
