ID A0A179UKJ9_BLAGS Unreviewed; 565 AA.
AC A0A179UKJ9;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Ubiquitin conjugating enzyme E2 {ECO:0000313|EMBL:OAT07541.1};
GN ORFNames=BDBG_03592 {ECO:0000313|EMBL:OAT07541.1};
OS Blastomyces gilchristii (strain SLH14081) (Blastomyces dermatitidis).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Ajellomycetaceae; Blastomyces.
OX NCBI_TaxID=559298 {ECO:0000313|EMBL:OAT07541.1, ECO:0000313|Proteomes:UP000002038};
RN [1] {ECO:0000313|Proteomes:UP000002038}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SLH14081 {ECO:0000313|Proteomes:UP000002038};
RX PubMed=26439490; DOI=10.1371/journal.pgen.1005493;
RA Munoz J.F., Gauthier G.M., Desjardins C.A., Gallo J.E., Holder J.,
RA Sullivan T.D., Marty A.J., Carmen J.C., Chen Z., Ding L., Gujja S.,
RA Magrini V., Misas E., Mitreva M., Priest M., Saif S., Whiston E.A.,
RA Young S., Zeng Q., Goldman W.E., Mardis E.R., Taylor J.W., McEwen J.G.,
RA Clay O.K., Klein B.S., Cuomo C.A.;
RT "The dynamic genome and transcriptome of the human fungal pathogen
RT Blastomyces and close relative Emmonsia.";
RL PLoS Genet. 11:E1005493-E1005493(2015).
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DR EMBL; GG657452; OAT07541.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A179UKJ9; -.
DR STRING; 559298.A0A179UKJ9; -.
DR VEuPathDB; FungiDB:BDBG_03592; -.
DR OrthoDB; 179223at2759; -.
DR Proteomes; UP000002038; Unassembled WGS sequence.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:UniProt.
DR CDD; cd00195; UBCc; 1.
DR Gene3D; 3.10.110.10; Ubiquitin Conjugating Enzyme; 1.
DR InterPro; IPR000608; UBQ-conjugat_E2.
DR InterPro; IPR023313; UBQ-conjugating_AS.
DR InterPro; IPR016135; UBQ-conjugating_enzyme/RWD.
DR PANTHER; PTHR24068:SF126; UBC CORE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR24068; UBIQUITIN-CONJUGATING ENZYME E2; 1.
DR Pfam; PF00179; UQ_con; 1.
DR SMART; SM00212; UBCc; 1.
DR SUPFAM; SSF54495; UBC-like; 1.
DR PROSITE; PS00183; UBC_1; 1.
DR PROSITE; PS50127; UBC_2; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022840};
KW Reference proteome {ECO:0000313|Proteomes:UP000002038};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786}.
FT DOMAIN 3..157
FT /note="UBC core"
FT /evidence="ECO:0000259|PROSITE:PS50127"
FT REGION 240..275
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 316..343
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 392..565
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 254..268
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 401..435
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 436..450
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 461..505
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 520..549
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 95
FT /note="Glycyl thioester intermediate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10133"
SQ SEQUENCE 565 AA; 61192 MW; 33287F4838961711 CRC64;
MASSFRRLAS DHASLHRGGL PPHYLFPPSS TSSSFSDDLT QLTVLLTGPQ GTPYSQGLWQ
LHLRIPEDYP KNPPKVAFKT RIWHPNVDES TGAVCVDTLK RDWEAKLTLR DVLITISCLL
IHPNPDSALN SAAGSLLRDD YEAFARQAKL MTSIHAPIPK DIKDAVMEAK RRGDESGIVI
TEDEDRLAAA IGSRKTASTS SVSTVIMKKP VTQRKQSSLR TEKLDIRVKQ TCQHGLLSSL
QSSSSPFMQD QQQQPHEDES DNEDTGSPSK ENDPSLSLSL VAISPCSSRK GVLGKRPLAV
LASPSEPEFV LVNSGAAADD DDDDDMNNAH SRSNSNDDGL TPSERNIAAN ALAREQQEQQ
QQQIRTQQLE LPPRKSLKLS VLSRGVNASG RIREDYRDPV STLAHNNNSN KESRGNGGKQ
VDRAGSSQSS ILSLSPPSPT PTPQPLLQPP NEKPSDDGKE NEASTASTII IPTAASTTTT
TTTTPTTTTT TTTTANNKSQ QQNQKQKFPP PPPPFPSSIS VPKSSNTNGN NKSNNNINNI
NNNITARRVS SAPAKAKPRV GLRRL
//
