ID   A0A179UQD5_BLAGS        Unreviewed;       617 AA.
AC   A0A179UQD5;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   27-MAR-2024, entry version 28.
DE   SubName: Full=Pre-mRNA splicing factor {ECO:0000313|EMBL:OAT10305.1};
GN   ORFNames=BDBG_05966 {ECO:0000313|EMBL:OAT10305.1};
OS   Blastomyces gilchristii (strain SLH14081) (Blastomyces dermatitidis).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Ajellomycetaceae; Blastomyces.
OX   NCBI_TaxID=559298 {ECO:0000313|EMBL:OAT10305.1, ECO:0000313|Proteomes:UP000002038};
RN   [1] {ECO:0000313|Proteomes:UP000002038}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SLH14081 {ECO:0000313|Proteomes:UP000002038};
RX   PubMed=26439490; DOI=10.1371/journal.pgen.1005493;
RA   Munoz J.F., Gauthier G.M., Desjardins C.A., Gallo J.E., Holder J.,
RA   Sullivan T.D., Marty A.J., Carmen J.C., Chen Z., Ding L., Gujja S.,
RA   Magrini V., Misas E., Mitreva M., Priest M., Saif S., Whiston E.A.,
RA   Young S., Zeng Q., Goldman W.E., Mardis E.R., Taylor J.W., McEwen J.G.,
RA   Clay O.K., Klein B.S., Cuomo C.A.;
RT   "The dynamic genome and transcriptome of the human fungal pathogen
RT   Blastomyces and close relative Emmonsia.";
RL   PLoS Genet. 11:E1005493-E1005493(2015).
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC   -!- SIMILARITY: Belongs to the PRP31 family.
CC       {ECO:0000256|ARBA:ARBA00005572}.
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DR   EMBL; GG657459; OAT10305.1; -; Genomic_DNA.
DR   RefSeq; XP_002623792.1; XM_002623746.1.
DR   AlphaFoldDB; A0A179UQD5; -.
DR   STRING; 559298.A0A179UQD5; -.
DR   GeneID; 8503585; -.
DR   KEGG; bgh:BDBG_05966; -.
DR   VEuPathDB; FungiDB:BDBG_05966; -.
DR   OrthoDB; 4493115at2759; -.
DR   Proteomes; UP000002038; Unassembled WGS sequence.
DR   GO; GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
DR   GO; GO:0046540; C:U4/U6 x U5 tri-snRNP complex; IEA:InterPro.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0000244; P:spliceosomal tri-snRNP complex assembly; IEA:InterPro.
DR   Gene3D; 1.10.287.4070; -; 1.
DR   Gene3D; 1.10.246.90; Nop domain; 1.
DR   InterPro; IPR042239; Nop_C.
DR   InterPro; IPR002687; Nop_dom.
DR   InterPro; IPR036070; Nop_dom_sf.
DR   InterPro; IPR012976; NOSIC.
DR   InterPro; IPR027105; Prp31.
DR   InterPro; IPR019175; Prp31_C.
DR   PANTHER; PTHR13904; PRE-MRNA SPLICING FACTOR PRP31; 1.
DR   PANTHER; PTHR13904:SF0; U4_U6 SMALL NUCLEAR RIBONUCLEOPROTEIN PRP31; 1.
DR   Pfam; PF01798; Nop; 1.
DR   Pfam; PF09785; Prp31_C; 1.
DR   SMART; SM00931; NOSIC; 1.
DR   SUPFAM; SSF89124; Nop domain; 1.
DR   PROSITE; PS51358; NOP; 1.
PE   3: Inferred from homology;
KW   mRNA processing {ECO:0000256|ARBA:ARBA00022664};
KW   mRNA splicing {ECO:0000256|ARBA:ARBA00023187};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002038};
KW   Ribonucleoprotein {ECO:0000256|ARBA:ARBA00023274};
KW   Ribosome biogenesis {ECO:0000256|ARBA:ARBA00022517};
KW   RNA-binding {ECO:0000256|ARBA:ARBA00022884};
KW   Spliceosome {ECO:0000256|ARBA:ARBA00022728}.
FT   DOMAIN          275..393
FT                   /note="Nop"
FT                   /evidence="ECO:0000259|PROSITE:PS51358"
FT   REGION          1..62
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          390..427
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          558..617
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        573..589
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   617 AA;  66053 MW;  8C0DB6C116095004 CRC64;
     MVTLADELLN DFEESGSEDE GKVANTLFPD SVGEPDLDTS AKARGEGMEL DGDEEEGNDD
     EADVDVAIDP TGKLAKEMGE AEATKAKVEK MRLGAVSDVR SVASLMKTLQ PILDKVSYYQ
     SLPPDKRTTA IGSIEDNPEY HLLTEANSLS TSIDNEMILV HKFIRDHYST RFPELETLIT
     NPLDYAKTVA ILQNGPLDDI KSLSTSTDNL VGATLRSVLD GPSLMIVAVE GTTTRGRELS
     QTELETVLDA CKMMLSLDRA KGILTDYVQS RMNVFAPNLT VLIGSLTAAQ LLNYAGGLTG
     LAKTPSCNIP PLGSKKQTGT GFATNVGVRH QGFLYHSPII QEIPNDLKRQ AMRIVSAKVV
     LAARVDRVHS SPDGSTGEEL KQACLDRLEK LTEPPPNKGP RALPAPDDKP SRKRGGRRAR
     KAKEATAMTE IRKAQNRMAF GKEEKEIGYG TGEGTKGLGM LGQEDHGRIR ASQIDQRTKA
     KLSKSNKGWG AATPIGGTAS SLRGFGQGAG NATVLRAQGL RTAGVGPSLG AGAGIASSIA
     FTPVQGLELV DPKAQAELNR KRKAEEDRWF KSGTFTQVGN QNNGGNSSGG FKVPELPRKR
     VDTGDTKMPP PPPPTNK
//