ID   A0A180EIP7_9BACT        Unreviewed;       816 AA.
AC   A0A180EIP7;
DT   02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT   02-NOV-2016, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   SubName: Full=Beta-galactosidase {ECO:0000313|EMBL:OAV43131.1};
GN   ORFNames=A3850_000860 {ECO:0000313|EMBL:OAV43131.1};
OS   Lewinella sp. 4G2.
OC   Bacteria; Bacteroidota; Saprospiria; Saprospirales; Lewinellaceae;
OC   Lewinella.
OX   NCBI_TaxID=1803372 {ECO:0000313|EMBL:OAV43131.1, ECO:0000313|Proteomes:UP000076582};
RN   [1] {ECO:0000313|EMBL:OAV43131.1, ECO:0000313|Proteomes:UP000076582}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=4G2 {ECO:0000313|EMBL:OAV43131.1,
RC   ECO:0000313|Proteomes:UP000076582};
RA   Wong S.-K., Yoshizawa S., Ogura Y., Tetsuya H., Nakajima Y., Hamasaki K.;
RT   "Lewinella sp. 4G2 Genome sequencing.";
RL   Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 2 family.
CC       {ECO:0000256|ARBA:ARBA00007401}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OAV43131.1}.
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DR   EMBL; LVWJ02000014; OAV43131.1; -; Genomic_DNA.
DR   RefSeq; WP_068213990.1; NZ_LVWJ02000014.1.
DR   AlphaFoldDB; A0A180EIP7; -.
DR   STRING; 1803372.A3850_000860; -.
DR   OrthoDB; 9801077at2; -.
DR   Proteomes; UP000076582; Unassembled WGS sequence.
DR   GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR   Gene3D; 3.20.20.80; Glycosidases; 1.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 2.
DR   InterPro; IPR036156; Beta-gal/glucu_dom_sf.
DR   InterPro; IPR032311; DUF4982.
DR   InterPro; IPR008979; Galactose-bd-like_sf.
DR   InterPro; IPR006101; Glyco_hydro_2.
DR   InterPro; IPR006103; Glyco_hydro_2_cat.
DR   InterPro; IPR006102; Glyco_hydro_2_Ig-like.
DR   InterPro; IPR006104; Glyco_hydro_2_N.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   InterPro; IPR013783; Ig-like_fold.
DR   PANTHER; PTHR42732; BETA-GALACTOSIDASE; 1.
DR   PANTHER; PTHR42732:SF1; BETA-MANNOSIDASE; 1.
DR   Pfam; PF16355; DUF4982; 1.
DR   Pfam; PF00703; Glyco_hydro_2; 1.
DR   Pfam; PF02836; Glyco_hydro_2_C; 1.
DR   Pfam; PF02837; Glyco_hydro_2_N; 1.
DR   PRINTS; PR00132; GLHYDRLASE2.
DR   SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR   SUPFAM; SSF49303; beta-Galactosidase/glucuronidase domain; 1.
DR   SUPFAM; SSF49785; Galactose-binding domain-like; 1.
PE   3: Inferred from homology;
KW   Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Reference proteome {ECO:0000313|Proteomes:UP000076582}.
FT   DOMAIN          62..184
FT                   /note="Glycosyl hydrolases family 2 sugar binding"
FT                   /evidence="ECO:0000259|Pfam:PF02837"
FT   DOMAIN          188..295
FT                   /note="Glycoside hydrolase family 2 immunoglobulin-like
FT                   beta-sandwich"
FT                   /evidence="ECO:0000259|Pfam:PF00703"
FT   DOMAIN          304..515
FT                   /note="Glycoside hydrolase family 2 catalytic"
FT                   /evidence="ECO:0000259|Pfam:PF02836"
FT   DOMAIN          636..699
FT                   /note="DUF4982"
FT                   /evidence="ECO:0000259|Pfam:PF16355"
SQ   SEQUENCE   816 AA;  92021 MW;  98442C856BC7627B CRC64;
     MKLLATIGLG IACLVLQATE SNRLAALEGP LVRTMINLNE GWQYSENNTA DLAAINQETH
     WEAIDLPHTW NQWDAMDAAP GYRRDASWYQ KDITVPEAAD GARYHLYFEG ANITTDVYVN
     GTRAGGHVGG YVGFEVDITD QVKPAEKNTV TIRVDNSYNP NVIPSQKADF FIYGGITRDL
     WLKVLPVTHI AHVAVATPEV SADRATTEVR VQLNQKNGRG KKAKVRCQLM DASGRVVAEE
     QMRVRKLPED GLITLPAITQ PALWSPDSPN LYTLKTQLLE GEQVVDEQVS TVGYRWFRFE
     PYGAFYLNGE RLLLRGTHRH EEHAGYGAAM PNALHVADIR LMKEMGVNFL RLGHYPQDPE
     VYRACNEMGI IVWDELPWCR GGLGEAEWQA NTERLLREQI NQNINHPSIL FWSLGNEIYW
     LPDFEGGDDE SAMNAYLTKL NTIAHTMDPY RQTAIRKYYA GADLVDVFSP SIWSGWYAGV
     YTNYGNTLKK NQQKYKQFLH MEYGGSSHVG RHTENPITGT GSVNEDDWAE VANQVNVKNI
     AKGGDWTETY IVDLFDYHLS VSETLPGFAG NAQWAFKDFG TPLRPQNAIP YVNQKGLVDR
     AGKPKDAFYV YKSYWGKEPF AYIESHTWTH RRGPKGKLRN IAVFSNCDEV ELLHDGKALG
     RKTRDITQAP ACGLNWDVNF KEGANKLVAR AYKDGNLIAT DEMTVSYDYQ QPGDPDRVHL
     EHKSLDNGNL LVEATMRDKN GLRVYDYEQE LYFTLDGQGE LLKHYGTPTR SNIIQMANGY
     AAIELTPAEF GRAIIEARNQ DFKGSYLVID FSTARK
//