ID   A0A180F7N2_9BACT        Unreviewed;       598 AA.
AC   A0A180F7N2;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   24-JAN-2024, entry version 21.
DE   SubName: Full=DNA mismatch repair protein mutS {ECO:0000313|EMBL:OAV67871.1};
GN   Name=mutS {ECO:0000313|EMBL:OAV67871.1};
GN   ORFNames=Barb6XT_01277 {ECO:0000313|EMBL:OAV67871.1};
OS   Bacteroidales bacterium Barb6XT.
OC   Bacteria; Bacteroidota; Bacteroidia; Bacteroidales.
OX   NCBI_TaxID=1633202 {ECO:0000313|EMBL:OAV67871.1, ECO:0000313|Proteomes:UP000078346};
RN   [1] {ECO:0000313|EMBL:OAV67871.1, ECO:0000313|Proteomes:UP000078346}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Barb6XT {ECO:0000313|EMBL:OAV67871.1,
RC   ECO:0000313|Proteomes:UP000078346};
RA   Tai V., Carpenter K.J., Weber P.K., Nalepa C.A., Perlman S.J.,
RA   Keeling P.J.;
RT   "Genomic and NanoSIMS analyses of nitrogen-fixing bacterial ectosymbionts
RT   of a protist inhabiting a wood-eating cockroach.";
RL   Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OAV67871.1}.
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DR   EMBL; LBCW01000073; OAV67871.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A180F7N2; -.
DR   PATRIC; fig|1633202.3.peg.3586; -.
DR   Proteomes; UP000078346; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR   GO; GO:0030983; F:mismatched DNA binding; IEA:InterPro.
DR   GO; GO:0006298; P:mismatch repair; IEA:InterPro.
DR   CDD; cd03283; ABC_MutS-like; 1.
DR   Gene3D; 1.10.1420.10; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR000432; DNA_mismatch_repair_MutS_C.
DR   InterPro; IPR007696; DNA_mismatch_repair_MutS_core.
DR   InterPro; IPR036187; DNA_mismatch_repair_MutS_sf.
DR   InterPro; IPR045076; MutS_family.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR11361; DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER; 1.
DR   PANTHER; PTHR11361:SF99; DNA MISMATCH REPAIR PROTEIN-RELATED; 1.
DR   Pfam; PF05192; MutS_III; 1.
DR   Pfam; PF00488; MutS_V; 1.
DR   SMART; SM00534; MUTSac; 1.
DR   SUPFAM; SSF48334; DNA repair protein MutS, domain III; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000078346};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        26..46
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        52..72
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        210..232
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        238..255
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          421..597
FT                   /note="DNA mismatch repair proteins mutS family"
FT                   /evidence="ECO:0000259|SMART:SM00534"
SQ   SEQUENCE   598 AA;  66956 MW;  AA975B8FCA580C11 CRC64;
     MKKVYAYYKG NVEAYSRCAG ELKKRIHLLG TVRLVLAVAG AVFFWLFREE SWLMLAGTIA
     LPALAFILLM VYHGRLFTQK VYTEALIALN KNELKGLDYD FGAFDGAADK GSAEHPFSLD
     LDVFGEHSLF QSVNRTVTGQ GRELLADWFL YPLCNKAEIE QRQEAVRELA EYSRLRQHFH
     VTGFVKKGNR DDGHFLTSLT GGRAYYANSI LWKVLLYAVP LAWAVILIGF AAGLVSGTVA
     GVYFGVSFLI ANWRAKPIND LYNRVDKMEK IFSVYSDLMR SIEGERFQAG ELVRISRQLT
     GSGGMTASRA VKQLSRHIGA LDQRFSLAGI LLNIFCLRDT RQALLLECWR EAHREDAVRW
     LDALGEFDAL ASLGGFAFNH PDYVFPDIAA SYFRMEGKDL GHPLLHRDVC VRNDMEIRKS
     PYFLIVTGAN MAGKSTYLRT AGVNYLLACI GAPVFASSLT VSPARLITGL RTSDSLTGNE
     SYFFAELKRL KMIIDRLKQG EELFIILDEI LKGTNSVDKQ KGSLALMRQL AACNTCGIIA
     THDLVLGTLA DNFPEAVKNY RFEADIKDDE LSFTYQLREG VARNMNACFL MKKMGITV
//