ID A0A180G7I0_PUCT1 Unreviewed; 1101 AA.
AC A0A180G7I0;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE RecName: Full=Exportin-T {ECO:0000256|ARBA:ARBA00018928, ECO:0000256|RuleBase:RU366037};
DE AltName: Full=Exportin(tRNA) {ECO:0000256|RuleBase:RU366037};
DE AltName: Full=tRNA exportin {ECO:0000256|RuleBase:RU366037};
GN ORFNames=PTTG_07067 {ECO:0000313|EMBL:OAV88646.1};
OS Puccinia triticina (isolate 1-1 / race 1 (BBBD)) (Brown leaf rust fungus).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Pucciniomycotina;
OC Pucciniomycetes; Pucciniales; Pucciniaceae; Puccinia.
OX NCBI_TaxID=630390 {ECO:0000313|EMBL:OAV88646.1};
RN [1] {ECO:0000313|EMBL:OAV88646.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1-1 BBBD Race 1 {ECO:0000313|EMBL:OAV88646.1};
RG The Broad Institute Genome Sequencing Platform;
RA Ward D., Feldgarden M., Earl A., Young S.K., Zeng Q., Koehrsen M.,
RA Alvarado L., Berlin A., Bochicchio J., Borenstein D., Chapman S.B.,
RA Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J., Griggs A.,
RA Gujja S., Heilman E., Heiman D., Hepburn T., Howarth C., Jen D., Larson L.,
RA Lewis B., Mehta T., Park D., Pearson M., Roberts A., Saif S., Shea T.,
RA Shenoy N., Sisk P., Stolte C., Sykes S., Thomson T., Walk T., White J.,
RA Yandava C., Izard J., Baranova O.V., Blanton J.M., Tanner A.C.,
RA Dewhirst F.E., Haas B., Nusbaum C., Birren B.;
RL Submitted (NOV-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:OAV88646.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1-1 BBBD Race 1 {ECO:0000313|EMBL:OAV88646.1};
RA Cuomo C.A., Bakkeren G., Szabo L., Khalil H., Joly D., Goldberg J.,
RA Young S., Zeng Q., Fellers J.;
RT "Comparative analysis highlights variable genome content of wheat rusts and
RT divergence of the mating loci.";
RL Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: tRNA nucleus export receptor which facilitates tRNA
CC translocation across the nuclear pore complex.
CC {ECO:0000256|RuleBase:RU366037}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496,
CC ECO:0000256|RuleBase:RU366037}. Nucleus
CC {ECO:0000256|RuleBase:RU366037}. Note=Shuttles between the nucleus and
CC the cytoplasm. {ECO:0000256|RuleBase:RU366037}.
CC -!- SIMILARITY: Belongs to the exportin family.
CC {ECO:0000256|ARBA:ARBA00009466, ECO:0000256|RuleBase:RU366037}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OAV88646.1}.
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DR EMBL; ADAS02000162; OAV88646.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A180G7I0; -.
DR STRING; 630390.A0A180G7I0; -.
DR VEuPathDB; FungiDB:PTTG_07067; -.
DR OrthoDB; 2546268at2759; -.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR GO; GO:0000049; F:tRNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0071528; P:tRNA re-export from nucleus; IEA:UniProtKB-UniRule.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR013598; Exportin-1/Importin-b-like.
DR InterPro; IPR045546; Exportin-T_C.
DR InterPro; IPR040017; XPOT.
DR PANTHER; PTHR15952:SF11; EXPORTIN-T; 1.
DR PANTHER; PTHR15952; EXPORTIN-T/LOS1; 1.
DR Pfam; PF19282; Exportin-T; 1.
DR Pfam; PF08389; Xpo1; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|RuleBase:RU366037};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU366037};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|RuleBase:RU366037};
KW Transport {ECO:0000256|RuleBase:RU366037};
KW tRNA-binding {ECO:0000256|ARBA:ARBA00022555,
KW ECO:0000256|RuleBase:RU366037}.
FT DOMAIN 124..306
FT /note="Exportin-1/Importin-beta-like"
FT /evidence="ECO:0000259|Pfam:PF08389"
FT DOMAIN 386..1096
FT /note="Exportin-T C-terminal"
FT /evidence="ECO:0000259|Pfam:PF19282"
SQ SEQUENCE 1101 AA; 123921 MW; 42EB7931616C721B CRC64;
MASLDEQIHQ AVTAALNPGP LQSEGLHFLQ QLRSNPKDSW QPGLICFIAG AQNDQHDPHS
WAYKYPPQTR LFGLQLVDTM LQFSTSSEEE IGLKKACYET TRQQLCDYIH REFVEGSGEQ
GLAYLRNKVV QTLFLLFFQS YPNNWTDFFS SFADLTRRHP KASSPPDNSN QPLNPRTTDL
YLRLLHEISS ELSDALLRIN KPSFRLSRDA ELRDAIRERD AARIARETFG IVAESLEGLS
KNDINSNQGL FGKQAQECLE MGIRVVEDYA SWIDISLIVT PTWIPFLFQS LRLSNISIRL
AAADALICIV TKGMPASNRI QLYNLLGLVD VLKALKSGNN ARRQAGEWSD EEDQFSERLA
KILNGMGVEL CKVCDDSSVP LEVQAASLGL ATQLLPLLLS FVEEDVFASC ASVLPFSSAI
LSRYKKDKKL APDSHLTQDK RTFLCQLLRL IVIKIRYPPD DLFEWEPPAL PGETEDEDMV
VYHDRRRQLK TVVEAIAVID EALFQETIDP LVSNVLDHIN SGVGNASNVC WQEVELALVM
LYNYGEAVRG SGPTSIRSYV MIPPEEIKKH NKNKDYKINY SQYPLSSLGN LLLKASKAMI
TKFPHPSIAV QWFECVTRYH EFFEVFTGAI QDVLPMFLDD RGLHHPNSNI RFRCCYLFYR
FVLQGKPAIQ THFNPQGWQA IIDQLKDLIV IQAELPSQLL SNGSGDEHDV LVKAVQSSSA
FDSQLYLFEA VGILVSFFSA NSEQQVACLQ SILQPLITQM RTELKNRPLN PTDLINALKI
HHAIMAVGAI AKGFPNLSSN TSSSATFPWL QVFKTATDDI MSVTERLNDI RVLRDATRSS
FHKIVATIGM EALPHVPVLI NCLLDKLTKP ELVEFLSFVG QLVHKYKENF ISLLDSLLLP
LFSKIINFLD QPITGTDDVM SQSELRRGYF NLCNSIIGAQ MHGIFVSPNN QPHLETILKT
IIDQLQAKEV LIPDLRFGFG LLKNFSSIWL KAPQAGPSPL PGFELFLYHQ VVPLCFAIPC
KPGFDWSDAE SYLVLTEIIG ILKMLMTSRG EEFVEFLVGN LFPSMSCPPE KGQKLIKEIQ
ETTDLKPSRK PLVEFFGRNA K
//
