ID A0A180GAM8_PUCT1 Unreviewed; 858 AA.
AC A0A180GAM8;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=DNA mismatch repair proteins mutS family domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=PTTG_28561 {ECO:0000313|EMBL:OAV89786.1};
OS Puccinia triticina (isolate 1-1 / race 1 (BBBD)) (Brown leaf rust fungus).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Pucciniomycotina;
OC Pucciniomycetes; Pucciniales; Pucciniaceae; Puccinia.
OX NCBI_TaxID=630390 {ECO:0000313|EMBL:OAV89786.1};
RN [1] {ECO:0000313|EMBL:OAV89786.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1-1 BBBD Race 1 {ECO:0000313|EMBL:OAV89786.1};
RG The Broad Institute Genome Sequencing Platform;
RA Ward D., Feldgarden M., Earl A., Young S.K., Zeng Q., Koehrsen M.,
RA Alvarado L., Berlin A., Bochicchio J., Borenstein D., Chapman S.B.,
RA Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J., Griggs A.,
RA Gujja S., Heilman E., Heiman D., Hepburn T., Howarth C., Jen D., Larson L.,
RA Lewis B., Mehta T., Park D., Pearson M., Roberts A., Saif S., Shea T.,
RA Shenoy N., Sisk P., Stolte C., Sykes S., Thomson T., Walk T., White J.,
RA Yandava C., Izard J., Baranova O.V., Blanton J.M., Tanner A.C.,
RA Dewhirst F.E., Haas B., Nusbaum C., Birren B.;
RL Submitted (NOV-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:OAV89786.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1-1 BBBD Race 1 {ECO:0000313|EMBL:OAV89786.1};
RA Cuomo C.A., Bakkeren G., Szabo L., Khalil H., Joly D., Goldberg J.,
RA Young S., Zeng Q., Fellers J.;
RT "Comparative analysis highlights variable genome content of wheat rusts and
RT divergence of the mating loci.";
RL Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OAV89786.1}.
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DR EMBL; ADAS02000118; OAV89786.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A180GAM8; -.
DR STRING; 630390.A0A180GAM8; -.
DR VEuPathDB; FungiDB:PTTG_28561; -.
DR OrthoDB; 168255at2759; -.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR GO; GO:0030983; F:mismatched DNA binding; IEA:InterPro.
DR GO; GO:0051321; P:meiotic cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0006298; P:mismatch repair; IEA:InterPro.
DR Gene3D; 1.10.1420.10; -; 2.
DR Gene3D; 3.30.420.110; MutS, connector domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR017261; DNA_mismatch_repair_MutS/MSH.
DR InterPro; IPR000432; DNA_mismatch_repair_MutS_C.
DR InterPro; IPR007696; DNA_mismatch_repair_MutS_core.
DR InterPro; IPR036187; DNA_mismatch_repair_MutS_sf.
DR InterPro; IPR036678; MutS_con_dom_sf.
DR InterPro; IPR045076; MutS_family.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR11361; DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER; 1.
DR PANTHER; PTHR11361:SF21; MUTS PROTEIN HOMOLOG 4; 1.
DR Pfam; PF05192; MutS_III; 1.
DR Pfam; PF00488; MutS_V; 1.
DR PIRSF; PIRSF037677; DNA_mis_repair_Msh6; 1.
DR SMART; SM00534; MUTSac; 1.
DR SMART; SM00533; MUTSd; 1.
DR SUPFAM; SSF48334; DNA repair protein MutS, domain III; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Meiosis {ECO:0000256|ARBA:ARBA00023254};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT DOMAIN 204..574
FT /note="DNA mismatch repair protein MutS core"
FT /evidence="ECO:0000259|SMART:SM00533"
FT DOMAIN 596..786
FT /note="DNA mismatch repair proteins mutS family"
FT /evidence="ECO:0000259|SMART:SM00534"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 858 AA; 95037 MW; 3E5B9AABF3A303F4 CRC64;
MSTSTSRPHT KPETVDNNPS EQLGSWIVAV TESRGVGREV GIVGFELQFG QIILSQLADS
QTYAKTIHWL RQRPPSHLLL VAPASPNSLT ILHTTLKHLF PAIPLTVLPR ASFASEKGYS
LLQDLCSAGP QSEATLAEVR QKYYALGAAS AVIDWIHKRL IQTGKSHWER HSLNVKWLSV
EGCMLIDRNT AVDLELINNA VSSKSKQSLF GLLNHTYTPM ANRLLRSNLL APPTEIEVID
GRLDAVEELI ELEDSFFNLR KSLKLLTQID LDKLIGGIIS TELASNRSSC NSQSGSLSMT
SLPSSSKKKK TAAIDPSIAI TKKLELLKSL RTILQSLNPI RSALSNCSSE LLRLASNIFQ
DAFLDEMASV IQFRVNEDSF LGIQKGSLAK QNVHAYAIKA GVENQLLNVA RETYKENLSD
AMAMCEALKE EYHLPKLQFV FETRTGFMLQ MKKDDLRATS KDSAYHPDGL PKVFTNIVKR
GKTLHFTCLD LKKKNQLIIN SYQEICLLSE EVLDAIFEEF RKRVSTFFRL SEAISLLDML
ASFAHVATTR EYVRPEFTDT LAISDGRHPI KELFDSESDE FVPNSSTVSF IVSNGPTFML
IDMSGKSIFL RQIALMVVMA QVGCFCPAKY ASFPVFDALL TCLSKNDDIE AGLSTFSSEM
KTVSGILSSM AVCSNPLIII DELGRGTSPL EGVGIAHAFS EEIIKAKSFC FFATHFRELS
MTLSVYPNVA CLHLETILSK QEATMALQFP HKVHGGAVKN AGYGIELASI AALPHNVMSR
AKKISEEMAA LSTEVERNST TNKVLRRRKV LLEVCTTLKN LANHSKLPSS ELGRFLKDYQ
RDTIHRLQPD EDMSSSGS
//
