ID A0A180GHQ4_PUCT1 Unreviewed; 1985 AA.
AC A0A180GHQ4;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 24-JAN-2024, entry version 24.
DE RecName: Full=Rap-GAP domain-containing protein {ECO:0000259|PROSITE:PS50085};
GN ORFNames=PTTG_27831 {ECO:0000313|EMBL:OAV91852.1};
OS Puccinia triticina (isolate 1-1 / race 1 (BBBD)) (Brown leaf rust fungus).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Pucciniomycotina;
OC Pucciniomycetes; Pucciniales; Pucciniaceae; Puccinia.
OX NCBI_TaxID=630390 {ECO:0000313|EMBL:OAV91852.1};
RN [1] {ECO:0000313|EMBL:OAV91852.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1-1 BBBD Race 1 {ECO:0000313|EMBL:OAV91852.1};
RG The Broad Institute Genome Sequencing Platform;
RA Ward D., Feldgarden M., Earl A., Young S.K., Zeng Q., Koehrsen M.,
RA Alvarado L., Berlin A., Bochicchio J., Borenstein D., Chapman S.B.,
RA Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J., Griggs A.,
RA Gujja S., Heilman E., Heiman D., Hepburn T., Howarth C., Jen D., Larson L.,
RA Lewis B., Mehta T., Park D., Pearson M., Roberts A., Saif S., Shea T.,
RA Shenoy N., Sisk P., Stolte C., Sykes S., Thomson T., Walk T., White J.,
RA Yandava C., Izard J., Baranova O.V., Blanton J.M., Tanner A.C.,
RA Dewhirst F.E., Haas B., Nusbaum C., Birren B.;
RL Submitted (NOV-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:OAV91852.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1-1 BBBD Race 1 {ECO:0000313|EMBL:OAV91852.1};
RA Cuomo C.A., Bakkeren G., Szabo L., Khalil H., Joly D., Goldberg J.,
RA Young S., Zeng Q., Fellers J.;
RT "Comparative analysis highlights variable genome content of wheat rusts and
RT divergence of the mating loci.";
RL Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OAV91852.1}.
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DR EMBL; ADAS02000073; OAV91852.1; -; Genomic_DNA.
DR STRING; 630390.A0A180GHQ4; -.
DR VEuPathDB; FungiDB:PTTG_27831; -.
DR OrthoDB; 20915at2759; -.
DR GO; GO:0005634; C:nucleus; IEA:InterPro.
DR GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.
DR Gene3D; 3.40.50.11210; Rap/Ran-GAP; 1.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR035974; Rap/Ran-GAP_sf.
DR InterPro; IPR000331; Rap/Ran_GAP_dom.
DR InterPro; IPR018515; Tuberin-type_domain.
DR InterPro; IPR027107; Tuberin/Ral-act_asu.
DR PANTHER; PTHR10063; TUBERIN; 1.
DR PANTHER; PTHR10063:SF0; TUBERIN; 1.
DR Pfam; PF02145; Rap_GAP; 1.
DR Pfam; PF03542; Tuberin; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF111347; Rap/Ran-GAP; 1.
DR PROSITE; PS50085; RAPGAP; 1.
PE 4: Predicted;
KW GTPase activation {ECO:0000256|ARBA:ARBA00022468}.
FT DOMAIN 1557..1801
FT /note="Rap-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50085"
FT REGION 563..589
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 666..686
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 716..758
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 925..947
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1451..1505
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1782..1805
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1838..1959
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 666..683
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1784..1798
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1841..1855
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1858..1888
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1889..1909
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1910..1939
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1985 AA; 220245 MW; 027A5ECD1DAF7A69 CRC64;
MDSLERIAGW RAIHSQLTTL LGHSQHFATT TAHTPIQLEH YHHYFHNHTQ NTEHQHILSL
IDSLYQITNH GKLISGCTGL IQLVADLCAR SIDHLQASLP LLRANNLLLI PTHTQAPFLR
LPDPAPHSQI IQHAAGLLTQ IIKFSSPQLS TEHVKLIIHL FINRIGLRTS FEAHLTIVLD
YIDTLVTFGY VPTRPLLSQE LDGAALLIDL VRFVARIVGL QPLQATVNVL RALEPKQHSD
LIDLSSSDLT IPLQLVVEAT TPLDPAIIQQ AKACMKDLIR SPANQAIKSL LSTLTADDPR
IDECSKVGAI RCLRYAFEDY DQIYKQARPA AASSAEEEAS GVATSLTLLG LGLLLVKEPL
EHILSSPSRT SLAIDHEILM LIYDRLYFRL QPNKTSIIAN LMKEDDLDCC LELMLLFSKE
RLPHWINDSE WSLDFDLDDS ILPSPQDQLK DTQGTNQSPL VPFGKIFTLL FIRRAEETRC
AAADGAQDKL LELMSWNLIT IDKYYSLSII LSRYLSTPLK LSLIDQIQSD QVCSPENPSW
LSNLVLLLDG FFEFDVDRTT LTNNNNNNNN NNINKSTVKS SAPSGSSSPA DSQVRLLRLI
HEIFMEIRDL EEWREELLQE VVIPTLSRFL LLPDLRSCDN PVLIDLVMDL IREVTHNELV
NELLSNQDQT VGEQESHQDP TGNKSLDTYD RLRKLLMTTA KMGQLIDIED ITQLTQSTRS
TQQSDLDSIP PAQNEAIPNL SLPSTPFSTP SSLPLKASTT TSTTISNTIF SPHRLSSNNN
EQASQRCDPV FAKRQHDLSY KAVVTLIRML TDSLKISTGY SNAKCVSIFV DLIGLLRPAN
GLINSSSNPH SHQAQSGLPH SFSLGDLDHD LQRKADESQI DNRARLAILK CLLRLRADEE
HRIQFVRDLE IEGLAQIIGR VIDPSRSDAS ALPSPDKKAC VSPATSKPRA APTFFRENCE
PGATNMGKRS ASMTTNATAT IGTTEPSDEG KPLWTVPDNL NEFGWEPKIE TQSTHCLVTY
DHIVRKDWDP SQDHLSVKNN SPSTCHHVVR HMTILPIPDY LAVLIAILRY EVDWELVSYV
LCHLPGQLSN KHFTCEPRAS QQIHQLRRFL CSGIKTDTLL HQVRFPPRQR VKLTDAHAIS
YQTLSTLIAY KALFDKSQAD EMVGAFVKGL SKYKDTAKAC IHALSLACHE LQPSITKFLP
EILRGLTKIV SSAFVSVHIL ELLGFLGQIP SLYANLTEEE FKMIFGISLQ YITTHNQLQQ
LEESRSAHAS ANHHTPPRAA GISTSEISLA EDVELAFQQY VYFMAFYIIA LWFVSLKLPE
RKKYVTFITR KLVQACEGKQ GLDEPTEVCF DMLNRYTYSN AEPKPRMKQS KFNQIINSSL
GKSVRTTSWI IGNSILTIKC LSRPGWTEVC VKRPSGMVKM IWELENLSGD YGASEQDVLE
MVIRHRDTLN SAAPEDDGLG DETADAQQQQ KAEKPPGDRS PHQPRGEVSL ESVLEQSEEI
TRTTGIEPNY TNLSVEPSFF ALQLFPFGDL GSPTLEDSPS NFRPLKVPDQ PIFQRAVEMI
DYLPVVDFHK IGVIYVGPGQ TTEEEILGNR EGSKAYINFL SSLGQLVRLK GCEHYNTGGL
DSKNDSNGKF AYMWGDDITQ ICFHIATLMP TSRDEQPSGP DPIMAKKALI GNDFVVIVFN
DSGQEYRFDC LKSQFNFINI IIEPNTPINS TLNLHAGVQQ ELKFFKISLQ RKKGLPKIGP
IAENFKMISS SCLSDFVRRL SLHCNTFSQV YLACVGTDHR SPAPAPSASA QQTQDDHPNP
LRLHLHPGRR KLEFVSNWRA RLREIKRLKE RIAKLVPAPA PSAAPDDPGG KIPLVVPPPS
TSITTNSTTT TTVGSSSSST TGPASTLSTP APAPLPLLDP LPPSHPSTSP APLAATSNTT
PASLAPLPAA SSSSPSSAAS TPGPPNPAST STPTMSATTT TRRLSSMMFD VDLLAQNLDF
SSWTD
//
