ID A0A182DXG7_ONCOC Unreviewed; 1507 AA.
AC A0A182DXG7;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=ABC transporter domain-containing protein {ECO:0000313|WBParaSite:nOo.2.0.1.t00344-RA};
GN ORFNames=NOO_LOCUS344 {ECO:0000313|EMBL:VDK61944.1};
OS Onchocerca ochengi (Filarial nematode worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Onchocerca.
OX NCBI_TaxID=42157 {ECO:0000313|Proteomes:UP000077448, ECO:0000313|WBParaSite:nOo.2.0.1.t00344-RA};
RN [1] {ECO:0000313|Proteomes:UP000077448}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=22919073; DOI=10.1101/gr.138420.112;
RA Darby A.C., Armstrong S.D., Bah G.S., Kaur G., Hughes M.A., Kay S.M.,
RA Koldkaer P., Rainbow L., Radford A.D., Blaxter M.L., Tanya V.N.,
RA Trees A.J., Cordaux R., Wastling J.M., Makepeace B.L.;
RT "Analysis of gene expression from the Wolbachia genome of a filarial
RT nematode supports both metabolic and defensive roles within the
RT symbiosis.";
RL Genome Res. 22:2467-2477(2012).
RN [2] {ECO:0000313|WBParaSite:nOo.2.0.1.t00344-RA}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (JUN-2016) to UniProtKB.
RN [3] {ECO:0000313|EMBL:VDK61944.1, ECO:0000313|Proteomes:UP000271087}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Laetsch R D., Stevens L., Kumar S., Blaxter L. M.;
RL Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; UYRW01000032; VDK61944.1; -; Genomic_DNA.
DR STRING; 42157.A0A182DXG7; -.
DR WBParaSite; nOo.2.0.1.t00344-RA; nOo.2.0.1.t00344-RA; nOo.2.0.1.g00344.
DR Proteomes; UP000077448; Unassembled WGS sequence.
DR Proteomes; UP000271087; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd03263; ABC_subfamily_A; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR026082; ABCA.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR19229:SF269; ABC TRANSPORTER CED-7; 1.
DR PANTHER; PTHR19229; ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA; 1.
DR Pfam; PF00005; ABC_tran; 2.
DR SMART; SM00382; AAA; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 2.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000271087};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 267..291
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 311..328
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 913..931
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1042..1067
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1079..1100
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1107..1131
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1143..1162
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 441..691
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT DOMAIN 1202..1425
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
SQ SEQUENCE 1507 AA; 170587 MW; B0CD8CE58C4B9FC4 CRC64;
MLPVHHLHLL LTKELIVIRR SKVWSVVEIA IPLIISVPLI ALVLQNSSSI KHEAQFWESF
QVTGDWRDID RRLGNMQSIY SYCGILSRRN LGLVFPNNMD EKEISWTARE IEFRYLMNNS
ALHSHFFELN VKIFPTEAAM MEELLEDYHR SFMCTKYIAG IIFDEYNSST LRLSYTIRIR
QTEDPQTQWY VGDDIWESGG PYEILDDHFL INMVPNYWSL GILSLQYAID TVFLKGTDDK
KSNDSKFQLS LERIPEPPYF EKSVVKFLSF LIIFWQLFTL PCILHTVANI VSEKHSGIKT
ISSWLFFSTN FIYGAGAASF ALLMSCIFHT PGAATKGTIV IWLVTIVLTR LQVTDGSVLL
NIILSLNLNY AFICAHRAMQ DYMNRAIYLD NVYPSGDLPR KQWFFFLHQS NNKHQQCTFD
DSSDAQSDNI QKYEGNDQAD IDIRHLTKTY AVQPAVDSMS FRAYRGEITV LLGHNGAGKS
TTFSLITGLI SPTSGSIYIC GSRMESHSID HCQREIGFCP QYNALFNLLT VREHLEMFRK
LSGNTVDCVM ELMTDMQLDN VADISEISAM LKLIERNCIP KLLPNIVEIA ENLSGGMKRK
LCVGISLVGG RRIILLDEPT AGMDPASRQA VVELLQRCKR ERTILLTTHC MDEADLLGDR
IAIMVRGRLF CAGTSEFLKN RFGTGYLLSI DLVPRQSSHH SLIQKEQLLS IIRKHVPETK
KQSITPQQMT VLLPTESKKS FPNLFIDLEQ NAEKYGINSF GLSLNTLEQV FLKVGELEDA
DSTVPIDIEN MAEQQASILC SNSSVRSQNN VALALAASGI AAALLPAKEI AIPNAIGGVC
IQCSGQSLEL CGLDLKTDCF SHGQLYVACS RVGKPDNLHI YTDNETTKNI VDLQVIALLR
KRFICYRKQW PRFIWQIVFP VIVLLVVVFY MKNLSTRDEK RHEILLNAGR INPSVVLLQL
ENPETLFGRN VLQIVRNITG NSYKLVPPSE SMELSLAKLP KVPPPVSIAV MYNTKNSYIA
ATAFFNAKAR YGPQLRTRLN TFIYWLSVII SDLILYAFVC AIFIVILNEW LSNLKFDLLL
LWLMYLWPTL PLVYCVAFLI NHPARAYIFL IIITLIVALC ASIVSYIMMF IKPKLFPYLH
TAFLFTLPTY SMSYGLIMIL VADVNKDTSG LYSWEYESNL EDIDVKKERE CISQKRNAEL
SLAVRNLNKY YGNLHAVRDL TFGIEPGECF GLLGVNGAGK TTTFDMLTGV SIPDGGEAFI
NGRSILKKQL IGFCPQFDAL HPKLTARQTL QLLASLYGFA NPMKRVETLL EAVSLTAHAD
ICVEFLSGGQ RRRLSLAVAL ISQTDLILLD EPTAGIDPKA RRQIWCLLNA VREKRRAMLL
TSHSMTECEA LCNRIGIMDQ GSLIAIGTPQ HIKTRFGEKY TLIITISDQC RREDLICLVK
KIFPDSIEKD TYRTCLLWDI TKGESDRWSQ MYGKLCQLAA QFPWITDYSL TQTTLEGAFL
QLSQREK
//
